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Extract from the Register of European Patents

EP About this file: EP3778592

EP3778592 - PSMA-TARGETED RADIOPHARMACEUTICAL FOR DIAGNOSING AND TREATING PROSTATE CANCER [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  01.03.2024
Database last updated on 26.06.2024
FormerThe patent has been granted
Status updated on  24.03.2023
FormerGrant of patent is intended
Status updated on  27.11.2022
FormerExamination is in progress
Status updated on  14.10.2021
FormerRequest for examination was made
Status updated on  15.01.2021
FormerThe international publication has been made
Status updated on  05.10.2019
Most recent event   Tooltip01.03.2024No opposition filed within time limitpublished on 03.04.2024  [2024/14]
Applicant(s)For all designated states
Futurechem Co., Ltd.
2nd Floor
21 Yeonmujang 3-gil
Seongdong-gu
Seoul 04782 / KR
[2021/07]
Inventor(s)01 / CHI, Dae Yoon
2F, 21, Yeonmujang 3-gil Seongdong-gu
Seoul 04782 / KR
02 / LEE, Byoung Se
2F, 21, Yeonmujang 3-gil Seongdong-gu
Seoul 04782 / KR
03 / CHU, So Young
2F, 21, Yeonmujang 3-gil Seongdong-gu
Seoul 04782 / KR
04 / JEONG, Hyeon Jin
2F, 21, Yeonmujang 3-gil Seongdong-gu
Seoul 04782 / KR
05 / KIM, Min Hwan
2F, 21, Yeonmujang 3-gil Seongdong-gu
Seoul 04782 / KR
06 / LEE, Kyo Chul
No 105-1103, 22, Seolleung-ro 126-gil
Gangnam-gu, Seoul / KR
07 / LEE, Yong Jin
No 102-903, 30, Deongneung-ro 71-gil
Nowon-gu, Seoul / KR
 [2021/07]
Representative(s)Office Freylinger
P.O. Box 48
8001 Strassen / LU
[2021/07]
Application number, filing date19775196.929.03.2019
[2021/07]
WO2019KR03716
Priority number, dateKR2018003722630.03.2018         Original published format: KR 20180037226
[2021/07]
Filing languageKO
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019190266
Date:03.10.2019
Language:KO
[2019/40]
Type: A1 Application with search report 
No.:EP3778592
Date:17.02.2021
Language:EN
[2021/07]
Type: B1 Patent specification 
No.:EP3778592
Date:26.04.2023
Language:EN
[2023/17]
Search report(s)International search report - published on:KR03.10.2019
(Supplementary) European search report - dispatched on:EP11.12.2020
ClassificationIPC:C07D403/12, A61K51/04, A61P35/00, C07D257/02
[2021/07]
CPC:
C07D257/02 (EP); C07D403/12 (EP,KR); A61K51/0487 (US);
A61K51/0402 (EP); A61K51/0474 (KR); A61K51/0497 (EP);
A61P35/00 (EP,KR,US); C07F5/003 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/07]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:GEGEN PSMA GERICHTETES RADIOPHARMAZEUTIKUM ZUR DIAGNOSE UND BEHANDLUNG VON PROSTATAKREBS[2021/07]
English:PSMA-TARGETED RADIOPHARMACEUTICAL FOR DIAGNOSING AND TREATING PROSTATE CANCER[2021/07]
French:AGENTS RADIOPHARMACEUTIQUES CIBLÉS SUR PSMA POUR LE DIAGNOSTIC ET LE TRAITEMENT DU CANCER DE LA PROSTATE[2021/07]
Entry into regional phase28.10.2020Translation filed 
28.10.2020National basic fee paid 
28.10.2020Search fee paid 
28.10.2020Designation fee(s) paid 
28.10.2020Examination fee paid 
Examination procedure28.10.2020Examination requested  [2021/07]
21.06.2021Amendment by applicant (claims and/or description)
13.10.2021Despatch of a communication from the examining division (Time limit: M04)
06.12.2021Reply to a communication from the examining division
28.11.2022Communication of intention to grant the patent
15.03.2023Fee for grant paid
15.03.2023Fee for publishing/printing paid
15.03.2023Receipt of the translation of the claim(s)
Opposition(s)29.01.2024No opposition filed within time limit [2024/14]
Fees paidRenewal fee
28.10.2020Renewal fee patent year 03
18.02.2022Renewal fee patent year 04
18.01.2023Renewal fee patent year 05
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Lapses during opposition  TooltipSM26.04.2023
IS26.08.2023
[2024/08]
Former [2023/50]IS26.08.2023
Documents cited:Search[XI]WO2013022797  (MOLECULAR INSIGHT PHARM INC [US], et al) [X] 1-3,5-7,9-11 * claims 1-6, 33-37 * * paragraph [0105] * * page 0126 * [I] 4,8;
 [E]WO2019246445  (UNIV NEW YORK STATE RES FOUND [US]) [E] 1-3,5-7,9-11 * claims 1, 22, 41, 44-48, 50 ** page 70; compound 9 *;
 [X]  - MATTHIAS EDER ET AL, "68 Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging", BIOCONJUGATE CHEMISTRY, (20120418), vol. 23, no. 4, doi:10.1021/bc200279b, ISSN 1043-1802, pages 688 - 697, XP055043532 [X] 1-3,5-7 * scheme 1; page 691; compound 8 * * paragraph bridging pages 691 and 692;; compound 68Ga8 *

DOI:   http://dx.doi.org/10.1021/bc200279b
International search[X]US2017081298  (RAY SANGEETA [US], et al) [X] 1-11 * See abstract; and claims 1-22. *;
 [X]WO2017165473  (UNIV JOHNS HOPKINS [US]) [X] 1-11 * See abstract; pages 2, 3; claims 1-17; and figure 4. *;
 [X]  - KUMAR, A. et al., "Design of a Small-Molecule Drug Conjugate for Prostate Cancer Targeted Theranostics", Biocoruugate Chemistry, (20160000), vol. 27, doi:10.1021/acs.bioconjchem.6b00222, pages 1681 - 1689, XP055638802 [X] 1-11 * See abstract; compound 11; and formula 2. *

DOI:   http://dx.doi.org/10.1021/acs.bioconjchem.6b00222
 [X]  - PILLAI, M. R. A. et al., "Radiolabeled enzyme inhibitors and binding agents targeting PSMA: effective theranostic tools for imaging and therapy of prostate cancer", Nuclear Medicine and Biology, (20160000), vol. 43, doi:10.1016/j.nucmedbio.2016.08.006, pages 692 - 720, XP029774672 [X] 1-11 * See abstract; and figure 18(a). *

DOI:   http://dx.doi.org/10.1016/j.nucmedbio.2016.08.006
 [X]  - BANERJEE, S. R. et al., "Effect of chelators on the pharmacokinetics of 99mTc-labeled imaging agents for the prostate-specific membrane antigen (PSMA", Journal of Medicinal Chemistry, (20130000), vol. 56, doi:10.1021/jm400823w, pages 6108 - 6121, XP055280715 [X] 1-11 * See abstract; and figure 1. *

DOI:   http://dx.doi.org/10.1021/jm400823w
by applicant   - MARESCA, K. P. et al., J. Med. Chem., (20090000), vol. 52, pages 347 - 357
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