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EP About this file: EP3814499

EP3814499 - COMPOSITIONS AND METHODS FOR GENOMIC EDITING BY INSERTION OF DONOR POLYNUCLEOTIDES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  03.04.2021
Database last updated on 14.08.2024
FormerThe international publication has been made
Status updated on  03.01.2020
Formerunknown
Status updated on  25.10.2019
Most recent event   Tooltip28.06.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
CRISPR Therapeutics AG
Baarerstrasse 14
6300 Zug / CH
[2021/18]
Inventor(s)01 / CARLO, Troy, Dean
Baarerstrasse 14
6300 Zug / CH
02 / BOGORAD, Roman, Lvovitch
Baarerstrasse 14
6300 Zug / CH
 [2021/18]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2021/18]
Application number, filing date19787407.628.06.2019
[2021/18]
WO2019IB00833
Priority number, dateUS201862691573P28.06.2018         Original published format: US 201862691573 P
[2021/18]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2020003006
Date:02.01.2020
Language:EN
[2020/01]
Type: A2 Application without search report 
No.:EP3814499
Date:05.05.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 02.01.2020 takes the place of the publication of the European patent application.
[2021/18]
Search report(s)International search report - published on:EP05.03.2020
ClassificationIPC:C12N15/11, C12N15/90, A61K31/7088, A61K48/00
[2021/18]
CPC:
C12N15/111 (EP,IL); C12N15/113 (KR); C12N15/907 (EP,IL,KR,US);
A61K48/00 (EP,IL,KR); A61K48/0025 (EP,IL); C12N15/102 (KR);
C12N15/11 (IL,US); C12N9/22 (IL,KR,US); C12N2310/18 (IL,US);
C12N2310/20 (EP,IL,KR,US); C12N2320/33 (EP,IL,KR); C12N2800/80 (IL,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/18]
Extension statesBA27.01.2021
ME27.01.2021
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUR GENOMEDITIERUNG DURCH INSERTION VON DONORPOLYNUKLEOTIDEN[2021/18]
English:COMPOSITIONS AND METHODS FOR GENOMIC EDITING BY INSERTION OF DONOR POLYNUCLEOTIDES[2021/18]
French:COMPOSITIONS ET PROCÉDÉS D'ÉDITION GÉNOMIQUE PAR INSERTION DE POLYNUCLÉOTIDES DONNEURS[2021/18]
Entry into regional phase27.01.2021National basic fee paid 
27.01.2021Designation fee(s) paid 
27.01.2021Examination fee paid 
Examination procedure27.01.2021Examination requested  [2021/18]
27.01.2021Date on which the examining division has become responsible
11.08.2021Amendment by applicant (claims and/or description)
Fees paidRenewal fee
27.01.2021Renewal fee patent year 03
27.06.2022Renewal fee patent year 04
27.06.2023Renewal fee patent year 05
27.06.2024Renewal fee patent year 06
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Cited inInternational search[XA]WO2010029303  (ISIS INNOVATION [GB], et al) [X] 1-13,15,17-28,81-85,87-90,95,134 * figure 3; claims 1, 2; table 3 * * the whole document * [A] 14,16,29-80,86,91-94,98-133,135-147;
 [A]WO2017072590  (CRISPR THERAPEUTICS AG [CH]) [A] 1-147 * the whole document *;
 [A]WO2017077386  (CRISPR THERAPEUTICS AG [CH]) [A] 1-147 * the whole document *;
 [XAI]WO2018096356  (HORIZON DISCOVERY LTD [GB]) [X] 1-3,5-7,13,15,17-28,81,87-90,95,128-134,136 * figures 5C, 6; claims 1, 7 * * the whole document * [A] 14,16,29-79,98-127,135,137-147 [I] 91,92,96,97;
 [E]WO2019239361  (NOVARTIS AG [CH]) [E] 1-13,15,17-28,80-90,93-95,128-134,136 * example 1; claims 1-14, 19; table 1; sequences 16, 24 ** the whole document *;
 [XAI]  - S. J. ORLANDO ET AL, "Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology", NUCLEIC ACIDS RESEARCH ADVANCE ACCESS, GB, (20100608), vol. 38, no. 15, doi:10.1093/nar/gkq512, ISSN 0305-1048, pages e152 - 1, XP055076783 [X] 1-13,15,17-28,80-90,93-95,128-130,134,136 * figure 4 * * the whole document * [A] 14,16,29-79,98-127,135,137-147 [I] 91,92,96,97,131-133

DOI:   http://dx.doi.org/10.1093/nar/gkq512
 [XAI]  - SHENGDAR Q TSAI ET AL, "GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases", NATURE BIOTECHNOLOGY, New York, (20141216), vol. 33, no. 2, doi:10.1038/nbt.3117, ISSN 1087-0156, pages 187 - 197, XP055555627 [X] 1-13,15,17-20,22,80-82,87-90,93-95,128-130,134,136 * the whole document * [A] 14,16,29-79,98-127,135,137-147 [I] 91,92,96,97,131-133

DOI:   http://dx.doi.org/10.1038/nbt.3117
 [A]  - ERIK VAN DER WAL ET AL, "Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies", STEM CELL REPORTS, United States, (20180503), vol. 10, no. 6, doi:10.1016/j.stemcr.2018.04.002, ISSN 2213-6711, pages 1975 - 1990, XP055657928 [A] 1-147 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.stemcr.2018.04.002
 [A]  - CHENGZU LONG ET AL, "Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing", SCIENCE ADVANCES, (20180131), vol. 4, no. 1, doi:10.1126/sciadv.aap9004, page eaap9004, XP055523128 [A] 1-147 * the whole document *

DOI:   http://dx.doi.org/10.1126/sciadv.aap9004
 [A]  - JEAN-BAPTISTE RENAUD ET AL, "Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases", CELL REPORTS, US, (20160225), vol. 14, no. 9, doi:10.1016/j.celrep.2016.02.018, ISSN 2211-1247, pages 2263 - 2272, XP055566276 [A] 1-147 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.celrep.2016.02.018
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