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Extract from the Register of European Patents

EP About this file: EP3797114

EP3797114 - HUMAN-DERIVED ANTI-(POLY-GA) DIPEPTIDE REPEAT (DPR) ANTIBODY [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  09.05.2024
Database last updated on 06.07.2024
FormerRequest for examination was made
Status updated on  26.02.2021
FormerThe international publication has been made
Status updated on  02.11.2019
Most recent event   Tooltip05.06.2024New entry: Additional fee for renewal fee: despatch of communication + time limit 
Applicant(s)For all designated states
Biogen MA Inc.
225 Binney Street
Cambridge, MA 02142 / US
For all designated states
Neurimmune AG
Wagistrasse 18
8952 Schlieren / CH
[2021/13]
Inventor(s)01 / GRIMM, Jan
Neurimmune AG Wagistrasse 13
8952 Schlieren / CH
02 / MONTRASIO, Fabio
Neurimmune AG Wagistrasse 13
8952 Schlieren / CH
03 / DALKILIC-LIDDLE, Isin
Biogen MA Inc. 225 Binney Street
Cambridge, Massachusetts 02142 / US
04 / RUSHE, Mia Marie
Biogen MA Inc. 225 Binney Street
Cambridge, Massachusetts 02142 / US
05 / ARNDT, Joseph Walter
Biogen MA Inc. 225 Binney Street
Cambridge, Massachusetts 02142 / US
 [2021/13]
Representative(s)Pohlman, Sandra M.
df-mp Dörries Frank-Molnia & Pohlman
Patentanwälte Rechtsanwälte PartG mbB
Theatinerstrasse 16
80333 München / DE
[2021/13]
Application number, filing date19793769.125.04.2019
[2021/13]
WO2019US29109
Priority number, dateEP2018016988827.04.2018         Original published format: EP 18169888
US201862772809P29.11.2018         Original published format: US 201862772809 P
[2021/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019210054
Date:31.10.2019
Language:EN
[2019/44]
Type: A1 Application with search report 
No.:EP3797114
Date:31.03.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 31.10.2019 takes the place of the publication of the European patent application.
[2021/13]
Search report(s)International search report - published on:US31.10.2019
(Supplementary) European search report - dispatched on:EP11.04.2022
ClassificationIPC:C07K16/44, C07K16/18, A61K39/395, A61P25/28
[2022/19]
CPC:
C07K16/44 (EP,KR,US); A61K47/6835 (US); A61K49/0002 (US);
A61K51/10 (US); A61P21/00 (KR); A61P25/28 (EP);
G01N33/6893 (KR); A61K2039/505 (EP,KR); C07K2317/24 (KR,US);
C07K2317/33 (EP); C07K2317/55 (EP,KR); C07K2317/56 (EP,KR,US);
C07K2317/565 (EP,KR,US); C07K2317/92 (EP,KR); C07K2317/94 (EP,KR) (-)
Former IPC [2021/13]C07K5/06, C07K16/44
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/13]
Extension statesBA27.11.2020
ME27.11.2020
Validation statesKH27.11.2020
MA27.11.2020
MD27.11.2020
TN27.11.2020
TitleGerman:VOM MENSCHEN STAMMENDE ANTIKÖRPER GEGEN (POLY-GA)DIPEPTID-REPEAT (DPR)[2021/13]
English:HUMAN-DERIVED ANTI-(POLY-GA) DIPEPTIDE REPEAT (DPR) ANTIBODY[2021/13]
French:ANTICORPS ANTI-(POLY-GA) DIRIGÉ CONTRE DES RÉPÉTITIONS DIPEPTIDIQUES (DPR) D'ORIGINE HUMAINE[2021/13]
Entry into regional phase27.11.2020National basic fee paid 
27.11.2020Search fee paid 
27.11.2020Designation fee(s) paid 
27.11.2020Examination fee paid 
Examination procedure27.11.2020Examination requested  [2021/13]
30.11.2022Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
09.02.2023Amendment by applicant (claims and/or description)
08.05.2024Despatch of a communication from the examining division (Time limit: M04)
Request for further processing for:The application is deemed to be withdrawn due to failure to indicate the wish to proceed further with the application
09.02.2023Request for further processing filed
09.02.2023Full payment received (date of receipt of payment)
Request granted
17.02.2023Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
09.02.2023Request for further processing filed
09.02.2023Full payment received (date of receipt of payment)
Request granted
17.02.2023Decision despatched
Fees paidRenewal fee
15.04.2021Renewal fee patent year 03
20.03.2022Renewal fee patent year 04
20.04.2023Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.04.202406   M06   Not yet paid
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Documents cited:Search[Y]WO2014114303  (DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN [DE]) [Y] 1-15 * abstract, examples *;
 [IY]WO2016050822  (NEURIMMUNE HOLDING AG [CH]) [I] 1,2,5-15 * whole application, in particular pages 13-15, 50-52, examples, figures, claims * [Y] 3,4;
 [Y]  - ALAIN BECK ET AL, "Strategies and challenges for the next generation of therapeutic antibodies", NATURE REVIEWS IMMUNOLOGY, (20100501), vol. 10, no. 5, doi:10.1038/nri2747, ISSN 1474-1733, pages 345 - 352, XP055012390 [Y] 3,4 * abstract, p. 347, figure 1 *

DOI:   http://dx.doi.org/10.1038/nri2747
 [Y]  - DAVID MA MANN ET AL, "Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72", ACTA NEUROPATHOLOGICA COMMUNICATIONS, BIOMED CENTRAL LTD, LONDON, UK, (20131014), vol. 1, no. 1, doi:10.1186/2051-5960-1-68, ISSN 2051-5960, page 68, XP021165579 [Y] 1-15 * abstract, tables 1, 2 figures 1-4 *

DOI:   http://dx.doi.org/10.1186/2051-5960-1-68
 [A]  - BRIAN D. FREIBAUM ET AL, "The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD", FRONTIERS IN MOLECULAR NEUROSCIENCE, (20170213), vol. 10, doi:10.3389/fnmol.2017.00035, XP055497300 [A] 1-15 * abstract, pages 3-4 figures 1-2 *

DOI:   http://dx.doi.org/10.3389/fnmol.2017.00035
International search[A]WO2014114303  (DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN [DE]) [A] 1-3, 5-9 * entire document *;
 [A]US2017059586  (PETRUCELLI LEONARD [US], et al) [A] 1-3, 5-9 * entire document *;
 [A]WO2017136313  (UNIV TEXAS [US]) [A] 1-3, 5-9 * entire document *;
 [X]US2017247471  (MONTRASIO FABIO [CH], et al) [X] 1-3 * entire document *;
 [A]WO2018018031  (UNIV NEW YORK [US]) [A] 1-3, 5-9 * entire document *;
 [A]  - ZHOU et al., "Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins", EMBO Molecular Medicine, (20170328), vol. 9, no. 5, doi:10.15252/emmm.201607054, pages 687 - 702, XP055512670 [A] 1-3, 5-9 * . entire document *

DOI:   http://dx.doi.org/10.15252/emmm.201607054
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.