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Extract from the Register of European Patents

EP About this file: EP3787647

EP3787647 - DE-DIFFERENTIATED FIBROBLAST-CONDITIONED MEDIA FOR STIMULATION OF DISC REGENERATION [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  24.11.2022
Database last updated on 15.06.2024
FormerRequest for examination was made
Status updated on  05.02.2021
FormerThe international publication has been made
Status updated on  08.11.2019
Most recent event   Tooltip13.03.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Spinalcyte, LLC
16815 Royal Crest Dr. Suite 100
Houston TX 77058 / US
[2021/10]
Inventor(s)01 / O'HEERON, Pete
17006 Evergreen Elm Way
Houston, TX 77059 / US
02 / ICHIM, Thomas
c/o SpinalCyte, LLC
16815 Royal Crest Drive, Suite 100
Houston, Texas 77058 / US
 [2021/13]
Former [2021/10]01 / O'HEERON, Pete
17006 Evergreen Elm Way
Houston, TX 77059 / US
02 / ICHIM, Thomas
9255 Towne Centre Drive 450
San Diego, CA 92121 / US
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2021/10]J A Kemp LLP
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date19795797.003.05.2019
[2021/10]
WO2019US30570
Priority number, dateUS201862666777P04.05.2018         Original published format: US 201862666777 P
[2021/10]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019213501
Date:07.11.2019
Language:EN
[2019/45]
Type: A1 Application with search report 
No.:EP3787647
Date:10.03.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 07.11.2019 takes the place of the publication of the European patent application.
[2021/10]
Search report(s)International search report - published on:US07.11.2019
(Supplementary) European search report - dispatched on:EP21.10.2021
ClassificationIPC:A61K35/28, A61L27/38, A61K35/33, C12N5/077
[2021/47]
CPC:
A61K35/33 (EP,US); C12N5/0656 (EP,US); C12N5/0655 (EP);
C12N2500/02 (EP,US); C12N2501/065 (EP,US); C12N2501/105 (EP,US);
C12N2502/02 (EP); C12N2502/1323 (EP); C12N2502/45 (EP,US) (-)
Former IPC [2021/10]A61K35/28, A61L27/38
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/10]
TitleGerman:ENTDIFFERENZIERTE FIBROBLASTKONDITIONIERTE MEDIEN ZUR STIMULATION DER BANDSCHEIBENREGENERATION[2021/10]
English:DE-DIFFERENTIATED FIBROBLAST-CONDITIONED MEDIA FOR STIMULATION OF DISC REGENERATION[2021/10]
French:MILIEUX CONDITIONNÉS PAR DES FIBROBLASTES DÉDIFFÉRENCIÉS, DESTINÉS À LA STIMULATION DE LA RÉGÉNÉRATION DES DISQUES INTERVERTÉBRAUX[2021/10]
Entry into regional phase23.11.2020National basic fee paid 
23.11.2020Search fee paid 
23.11.2020Designation fee(s) paid 
23.11.2020Examination fee paid 
Examination procedure23.11.2020Examination requested  [2021/10]
18.05.2022Amendment by applicant (claims and/or description)
23.11.2022Despatch of a communication from the examining division (Time limit: M06)
27.04.2023Reply to a communication from the examining division
Fees paidRenewal fee
13.05.2021Renewal fee patent year 03
15.06.2022Renewal fee patent year 04
14.03.2023Renewal fee patent year 05
13.03.2024Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.05.202204   M06   Fee paid on   15.06.2022
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]US2007184033  (SEVRAIN LIONEL C [US], et al) [A] 1-15 * par. 12 *;
 [A]WO2010138517  (ADVANCED CELL TECH INC [US], et al) [A] 1-15 * par. 63 *;
 [A]CN104011201  (SPINALCYTE LLC) [A] 1-15 * par. 33, 49 *;
 [Y]  - CHENG XIAOFEI ET AL, "Mesenchymal stem cells deliver exogenous miR-21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration", JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, RO, vol. 22, no. 1, doi:10.1111/jcmm.13316, ISSN 1582-1838, (20170814), pages 261 - 276, URL: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjcmm.13316, XP055850572 [Y] 1-15 * p. 265, col. 1, par. 3, 4; p. 271, col. 1, par. 3; Fig. 1; Fig. 2; Fig. 6 *

DOI:   http://dx.doi.org/10.1111/jcmm.13316
 [Y]  - Pei-Lun Lai ET AL, "Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts", Scientific Reports, vol. 7, n. 1, doi:10.1038/srep44534, (20170317), pages 1 - 13, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356011/pdf/srep44534.pdf, (20191209), XP055650768 [Y] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1038/srep44534
 [A]  - D-Y Kim ET AL, "G-I. Im, MD Repair of cartilage defect in the rabbit with cultured mesenchymal stem cells from bone marrow", (20020101), URL: http://www.bjj.boneandjoint.org.uk/content/83-B/2/289.full.pdf, (20150415), XP055183038 [A] 1-15 * abstract *
International search[Y]US2016145575  (PIMANDA JOHN [AU], et al) [Y] 1-5, 17-19* para [0004], [0103], [0104], Claim 1, Claim 3, Claim 4 *;
 [Y]US2016220613  (LIM SAI KIANG [SG]) [Y] 1-5, 17-19 * para [0075], [0077], [0079]. [0086]. [0170], [0177] *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.