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Extract from the Register of European Patents

EP About this file: EP3880662

EP3880662 - NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.10.2023
Database last updated on 16.09.2024
FormerRequest for examination was made
Status updated on  20.08.2021
FormerThe international publication has been made
Status updated on  22.05.2020
Formerunknown
Status updated on  25.11.2019
Most recent event   Tooltip06.10.2023Application deemed to be withdrawnpublished on 08.11.2023  [2023/45]
Applicant(s)For all designated states
Universite de Rouen Normandie
1 rue Thomas Becket
76130 Mont-Saint-Aignan / FR
For all designated states
Université de Caen Normandie
Esplanade de la Paix
14000 Caen / FR
For all designated states
Institut National des Sciences Appliquées de Rouen (INSA)
685 Avenue de l'Université
76800 Saint-Etienne du Rouvray / FR
For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
3, rue Michel-Ange
75016 Paris / FR
For all designated states
Ecole Nationale Supérieure d'Ingénieurs de Caen
6, Boulevard du Maréchal Juin
14000 Caen / FR
[2021/38]
Inventor(s)01 / REBOUL, Vincent
1 Rue du Régiment de la Chaudière
14440 Douvres la Deliverande / FR
02 / FRANCK, Xavier
35 allée mercure
76230 Bois Gillaume / FR
03 / GLACHET, Thomas
73 avenue Georges Clémenceau
14000 Caen / FR
04 / MARZAG, Hamid
87 B rue de Coulmiers
45000 Orleans / FR
 [2021/38]
Representative(s)Regimbeau
20, rue de Chazelles
75847 Paris Cedex 17 / FR
[2021/38]
Application number, filing date19804716.914.11.2019
[2021/38]
WO2019EP81393
Priority number, dateFR2018006050714.11.2018         Original published format: FR 1860507
[2021/38]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2020099596
Date:22.05.2020
Language:FR
[2020/21]
Type: A1 Application with search report 
No.:EP3880662
Date:22.09.2021
Language:FR
The application published by WIPO in one of the EPO official languages on 22.05.2020 takes the place of the publication of the European patent application.
[2021/38]
Search report(s)International search report - published on:EP22.05.2020
ClassificationIPC:C07D229/02
[2021/38]
CPC:
C07D229/02 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/38]
Extension statesBA14.06.2021
ME14.06.2021
Validation statesMD14.06.2021
TitleGerman:NEUARTIGER WEG ZUR SYNTHESE VON DIAZIRINEN, DIE MIT WASSERSTOFF-15 ANGEREICHERT SEIN KÖNNEN ODER NICHT[2021/38]
English:NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15[2021/38]
French:NOUVELLE VOIE DE SYNTHESE DE DIAZIRINES, ENRICHIES OU NON EN AZOTE-15[2021/38]
Entry into regional phase14.06.2021National basic fee paid 
14.06.2021Designation fee(s) paid 
14.06.2021Examination fee paid 
Examination procedure14.06.2021Examination requested  [2021/38]
14.06.2021Date on which the examining division has become responsible
06.01.2022Amendment by applicant (claims and/or description)
01.06.2023Application deemed to be withdrawn, date of legal effect  [2023/45]
23.06.2023Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2023/45]
Fees paidRenewal fee
05.10.2021Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
30.11.202204   M06   Not yet paid
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Cited inInternational search[A]  - Mingyou Hu ET AL, "S-1 Supporting Information gem-Difluoroolefination of Diazo Compounds with TMSCF 3 or TMSCF 2 Br: Transition-Metal-Free Cross-Coupling of Two Carbene Precursors 3.1 Full Screening of Condition for Reaction of 1a with TMSCF 3 (Table S1)", (20151026), URL: https://pubs.acs.org/doi/suppl/10.1021/jacs.5b09888/suppl_file/ja5b09888_si_001.pdf, (20190717), XP055606590 [A] 1-9 * pages S-6 *
 [A]  - Kun Shen ET AL, "Supporting Information Diazirines as Potential Molecular Imaging Tags: Probing the Requirements for Efficient and Long-Lived SABRE-Induced Hyperpolarization", (20170629), URL: https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002/anie.201704970&file=anie201704970-sup-0001-misc_information.pdf, (20190716), XP055606162 [A] 1-9 * compounds 2-5 *
 [A]  - Guojiao Wu ET AL, "Supporting Information for Metal-Free Oxidative Cross-Coupling of Diazirines with Arylboronic Acids CONTENTS", (20151202), URL: http://www.rsc.org/suppdata/c5/cc/c5cc08855k/c5cc08855k1.pdf, (20190718), XP055606961 [A] 1-9 * page S2 - page S3 *
 [A]  - ERNI B ET AL, "FATTY ACIDS CONTAINING PHOTOACTIVABLE CARBENE PRECURSORS. SYNTHESISAND PHOTOCHEMICAL PROPERTIES OF 3,3-BIS(1,1-DIFLUOROHEXYL)DIAZIRINEAND 3-(1,1-DIFLUOROOCTYL)-3H-DIAZIRINE", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, (19800521), vol. 102, no. 11, doi:10.1021/JA00531A034, ISSN 0002-7863, pages 3888 - 3896, XP001013157 [A] 1-9 * scheme III and V; page 3890 *

DOI:   http://dx.doi.org/10.1021/ja00531a034
 [A]  - MOHAMMAD AL-OMARI ET AL, "Bi-3H-diazirin-3-yls as Precursors of Highly Strained Cycloalkynes", ANGEWANDTE CHEMIE, INTERNATIONAL EDITION, DE, (2006), vol. 45, no. 2, doi:10.1002/anie.200503124, ISSN 1433-7851, pages 309 - 311, XP055606972 [A] 1-9 * scheme 3, 4 *

DOI:   http://dx.doi.org/10.1002/anie.200503124
by applicantWO2016049123
 WO2016096897
 WO2010076490
 WO2017045891
 WO2014081391
    - HILL, J. R.ROBERTSON, A. A. B., J. Med. Chem., (20180000), vol. 61, pages 6945 - 6963
    - THEIS, T.ORTIZ JR., G. X.LOGAN, A. W. J.CLAYTON, K. E.FENG, Y.HUHN, W. P.BLUM, V.MALCOLMSON, S. J.CHEKMENEV, E. Y.WANG, Q., Science Advances, (20160000), vol. 2, page e1501438
    - SHEN, K.LOGAN, A. W. J.COLELL, J. F. P.BAE, J.ORTIZ JR., G. X.THEIS, T.WARREN, W. S.MALCOLMSON, S. J.WANG, Q., Angew. Chem. Int. Ed., (20170000), vol. 56, page 12112
    - ZAKARIAN, A. et al., J. Am. Chem. Soc., (20180000), vol. 140, pages 6027 - 6032
    - HARRISON et al., Compendium of Synthetic Organic Methods, J. Wiley & sons, (19710000), vol. 1 à 8
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