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Extract from the Register of European Patents

EP About this file: EP3813848

EP3813848 - PERSONALIZED CANCER VACCINE EPITOPE SELECTION [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  03.04.2021
Database last updated on 26.07.2024
FormerThe international publication has been made
Status updated on  03.01.2020
Most recent event   Tooltip14.06.2024Change - applicantpublished on 17.07.2024  [2024/29]
Applicant(s)For all designated states
ModernaTX, Inc.
325 Binney Street
Cambridge, MA 02142 / US
[2024/29]
Former [2021/18]For all designated states
ModernaTX, Inc.
200 Technology Square
Cambridge, MA 02139 / US
Inventor(s)01 / ZHONG, Shan
200 Technology Square
Cambridge, MA 02139 / US
02 / BRETON, Benjamin
200 Technology Square
Cambridge, MA 02141 / US
03 / MCFADYEN, Iain
11 Amherst Street
Arlington, MA 02474 / US
04 / HOPSON, Kristen
331 Appleton Street
Arlington, MA 02476 / US
05 / LUCZKOW, Vincent
200 Technology Square
Cambridge, MA 02141 / US
06 / GARNAAS, Maija
112 Highland Avenue, Unit B
Somerville, MA 02143 / US
 [2021/18]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2021/18]
Application number, filing date19826546.427.06.2019
[2021/18]
WO2019US39521
Priority number, dateUS201862690441P27.06.2018         Original published format: US 201862690441 P
US201862757045P07.11.2018         Original published format: US 201862757045 P
US201962814200P05.03.2019         Original published format: US 201962814200 P
US201962855311P31.05.2019         Original published format: US 201962855311 P
[2021/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020006242
Date:02.01.2020
Language:EN
[2020/01]
Type: A1 Application with search report 
No.:EP3813848
Date:05.05.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 02.01.2020 takes the place of the publication of the European patent application.
[2021/18]
Search report(s)International search report - published on:AU02.01.2020
(Supplementary) European search report - dispatched on:EP22.06.2022
ClassificationIPC:A61K31/7105, A61K31/711, A61K31/7115, A61K39/00, C12Q1/6886, G01N33/574
[2021/18]
CPC:
G01N33/57484 (EP,KR); A61P35/00 (EP,AU,KR,US); A61K39/0011 (EP,AU,KR,US);
A61K31/7105 (EP,KR); A61K31/711 (EP,KR); A61K31/7115 (EP,KR);
A61K48/0058 (AU); A61K48/0066 (AU); A61P37/04 (US);
G01N33/5011 (US); G01N33/574 (KR); G16B20/20 (EP,KR,US);
G16B20/30 (US); G16B30/00 (AU,US); G16B30/10 (EP,KR);
G16B40/00 (US); A61K2039/53 (EP,AU,KR,US); A61K2039/54 (US);
A61K2039/545 (US); A61K2039/57 (US); A61K2039/585 (KR);
A61K2039/70 (US); G01N2500/00 (EP,KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/18]
Extension statesBA13.01.2021
ME13.01.2021
Validation statesKH13.01.2021
MA13.01.2021
MD13.01.2021
TN13.01.2021
TitleGerman:EPITOPAUSWAHL FÜR PERSONALISIERTES KREBSVAKZIN[2021/18]
English:PERSONALIZED CANCER VACCINE EPITOPE SELECTION[2021/18]
French:SÉLECTION PERSONNALISÉE D'ÉPITOPES DE VACCINS CONTRE LE CANCER[2021/18]
Entry into regional phase13.01.2021National basic fee paid 
13.01.2021Search fee paid 
13.01.2021Designation fee(s) paid 
13.01.2021Examination fee paid 
Examination procedure13.01.2021Examination requested  [2021/18]
14.02.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
24.04.2023Amendment by applicant (claims and/or description)
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
24.04.2023Request for further processing filed
24.04.2023Full payment received (date of receipt of payment)
Request granted
02.05.2023Decision despatched
Fees paidRenewal fee
14.06.2021Renewal fee patent year 03
13.05.2022Renewal fee patent year 04
31.03.2023Renewal fee patent year 05
17.05.2024Renewal fee patent year 06
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Documents cited:Search[X]WO2017020026  (MODERNATX INC [US]) [X] 1-17 * page 1, line 31 - page 12, line 33 * * page 15, line 13 - line 33 * * page 17, line 21 - page 22, line 33 * * page 66, line 3 - page 67, line 22 * * page 70, line 11 - line 21; example -; claim - *;
 [X]WO2017070618  (MODERNATX INC [US]) [X] 1-17 * page 1, line 31 - page 16, line 26 * * page 23, line 9 - page 27, line 8 * * page 32, line 1 - page 37, line 28 * * page 71, line 5 - page 72, line 21; example -; claim - *;
 [XP]WO2018144082  (MODERNATX INC [US]) [XP] 1-17* page 2, line 6 - page 27, line 19; claim - *
International search[XY]WO2012159754  (BIONTECH AG [DE], et al) [X] 1-45, 47-91 * (D4 see: abstract; pages 2-4, 7, 9, 11, 16-17, 21-22, 25-26, 44-46, 51, 62, 77-79, Examples, Figures 6 and 8 and claims). (as above) * [Y] 1-45, 47-91;
 [XY]WO2014168874  (BROAD INST INC [US], et al) [X] 1-45 47-91 * (D5: see abstract, pages 2-4, 7, 16, 31-34, 53, claims) (as above) * [Y] 1-45, 47-91;
 [XY]WO2017020026  (MODERNATX INC [US]) [X] 1-45, 47-91 * (D1: see abstract, summary of the invention page 12, page 15-page 18, pages 20-22, pages 65-67, page 70, pages 127-129, claims). (as above) * [Y] 1-45, 47-91;
 [XY]WO2017070618  (MODERNATX INC [US]) [X] 1-45, 47-91 * (D2: see abstract, pages 4-5, page 13-14, page 24, page 26-27, page 36, page 71-72, pages 87, and claims). (as above) * [Y] 1-45, 47-91;
 [XP]WO2018144082  (MODERNATX INC [US]) [XP] 1-45, 47-91* (D8: see abstract, summary of the invention pages 2-26, claims) *;
 [XY]  - SAHIN, U. et al., "Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer", Nature, (20170713), vol. 547, no. 7662, doi:10.1038/nature23003, pages 222 - 226, XP002780019 [X] 1-45, 47-91 * . (D3: see abstract, page 222 both columns, page 223 left column, page 225 right column, page 227 both columns, and Extended Data Table 1). (as above) * [Y] 1-45, 47-91

DOI:   http://dx.doi.org/10.1038/nature23003
 [Y]  - ZHANG, X. et al., "Personalized cancer vaccines: Targeting the cancer mutanome", Vaccine, (20170215), vol. 35, no. 7, doi:10.1016/j.vaccine.2016.05.073, pages 1094 - 1100, XP029904248 [Y] 1-45, 47-91 * . (D6: see whole document, in particular Figure 2). *

DOI:   http://dx.doi.org/10.1016/j.vaccine.2016.05.073
 [Y]  - HARTMAIER, R.J. et al., "Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies", Genome Med, (20170224), vol. 9, no. 16, pages 1 - 9, XP055630548 [Y] 1-45, 47-91 * . (D7: see abstract and background) *

DOI:   http://dx.doi.org/10.1186/s13073-017-0408-2
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