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Extract from the Register of European Patents

EP About this file: EP3893928

EP3893928 - PRODUCTION OF VIRAL VACCINES ON AN AVIAN CELL LINE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.10.2023
Database last updated on 01.10.2024
FormerRequest for examination was made
Status updated on  17.09.2021
FormerThe international publication has been made
Status updated on  20.06.2020
Formerunknown
Status updated on  04.02.2020
Most recent event   Tooltip27.10.2023Application deemed to be withdrawnpublished on 29.11.2023  [2023/48]
Applicant(s)For all designated states
Université Claude Bernard Lyon 1
43 Boulevard du 11 Novembre 1918
69100 Villeurbanne / FR
For all designated states
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
3, rue Michel-Ange
75016 Paris / FR
For all designated states
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM
101, rue de Tolbiac
75013 Paris / FR
For all designated states
Université Laval
2325 rue de l'Université
Québec, Québec G1V 0A6 / CA
For all designated states
TRANSGENE
Parc d'Innovation
Boulevard Gonthier d'Andernach
67400 Illkirch Graffenstaden / FR
For all designated states
Ecole Normale Supérieure de Lyon
15 parvis René Descartes
69007 Lyon / FR
[2021/42]
Inventor(s)01 / ROSA-CALATRAVA, Manuel
9 bis rue du docteur Rebatel
69003 Lyon / FR
02 / BOIVIN, Guy
2531 Montbray
Quebec, Quebec G1V1E7 / CA
03 / DUBOIS, Julia
75 route du mas rillier
69140 Rillieux-La-Pape / FR
04 / PIZZORNO, Mario Andres
14 rue Domer
69007 Lyon / FR
05 / TERRIER, Olivier
67 rue Bataille
69008 Lyon / FR
06 / TRAVERSIER, Aurélien
104 Avenue Francis de Pressensé
69200 Venissieux / FR
 [2021/42]
Representative(s)Regimbeau
20, rue de Chazelles
75847 Paris Cedex 17 / FR
[2021/42]
Application number, filing date19842600.912.12.2019
[2021/42]
WO2019FR53036
Priority number, dateFR2018007295714.12.2018         Original published format: FR 1872957
[2021/42]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO2020120910
Date:18.06.2020
Language:FR
[2020/25]
Type: A1 Application with search report 
No.:EP3893928
Date:20.10.2021
Language:FR
The application published by WIPO in one of the EPO official languages on 18.06.2020 takes the place of the publication of the European patent application.
[2021/42]
Search report(s)International search report - published on:EP18.06.2020
ClassificationIPC:A61K39/12, A61P31/14, C12N7/04
[2021/42]
CPC:
A61K39/12 (EP,US); A61P31/12 (US); A61P31/14 (EP);
C12N7/00 (US); C12N7/04 (EP); A61K2039/5254 (US);
C12N2760/18334 (EP,US); C12N2760/18351 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/42]
TitleGerman:HERSTELLUNG VON VIRALEN IMPFSTOFFEN AUF EINER VOGELZELLINIE[2021/42]
English:PRODUCTION OF VIRAL VACCINES ON AN AVIAN CELL LINE[2021/42]
French:PRODUCTION DE VACCINS VIRAUX SUR UNE LIGNEE CELLULAIRE AVIAIRE[2021/42]
Entry into regional phase07.07.2021National basic fee paid 
07.07.2021Designation fee(s) paid 
07.07.2021Examination fee paid 
Examination procedure07.07.2021Examination requested  [2021/42]
07.07.2021Date on which the examining division has become responsible
04.05.2022Amendment by applicant (claims and/or description)
01.07.2023Application deemed to be withdrawn, date of legal effect  [2023/48]
21.07.2023Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2023/48]
Request for further processing for:04.05.2022Request for further processing filed
04.05.2022Full payment received (date of receipt of payment)
Request granted
13.05.2022Decision despatched
Fees paidRenewal fee
07.07.2021Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.12.202204   M06   Not yet paid
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Cited inInternational search[XAY]US2004241188  (COLLINS PETER L [US], et al) [X] 6-11 * page 27, paragraph [0201] - paragraph [0208]; claims 9,11,13,47,48 * * page 21, paragraph [0175] - page 24, paragraph [0188] * [A] 4,12 [Y] 1-3,5;
 [A]WO2009062532  (VIRONOVATIVE BV [NL], et al) [A] 1-12 * page 115, paragraph [00381]; table 8 *;
 [AD]WO2012001075  (TRANSGENE [FR], et al) [AD] 1-12 * example -; claims 3,6,7 *;
 [YD]  - PETIOT EMMA ET AL, "Influenza viruses production: Evaluation of a novel avian cell line DuckCelt -T17", VACCINE, ELSEVIER, AMSTERDAM, NL, (20170529), vol. 36, no. 22, doi:10.1016/J.VACCINE.2017.03.102, ISSN 0264-410X, pages 3101 - 3111, XP085393890 [YD] 1-3,5 * abstract * * page 3103, column l, paragraph 3 *

DOI:   http://dx.doi.org/10.1016/j.vaccine.2017.03.102
 [A]  - DUBOIS JULIA ET AL, "Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia", JOURNAL OF GENERAL VIROLOGY, (201706), vol. 98, no. 6, pages 1174 - 1180, XP002795008 [A] 4,12 * page 1174, column r, paragraph l *

DOI:   http://dx.doi.org/10.1099/jgv.0.000796
 [A]  - LE NOUEN CYRIL ET AL, "Human Metapneumovirus SH and G Glycoproteins Inhibit Macropinocytosis-Mediated Entry into Human Dendritic Cells and Reduce CD4(+) T Cell Activation", JOURNAL OF VIROLOGY, (201406), vol. 88, no. 11, pages 6453 - 6469, XP002795009 [A] 1-12 * abstract * * page 6463, column l, paragraph l - column r, paragraph 1 * * page 6467, column r, paragraph 2 *
by applicantWO2005014626
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DOI:   http://dx.doi.org/10.1016/j.vaccine.2017.03.102
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DOI:   http://dx.doi.org/10.1016/j.vaccine.2011.11.008
    - LIU PSHU ZQIN XDOU YZHAO YZHAO X, "A live attenuated human metapneumovirus vaccine strain provides complété protection against homologous viral infection and cross-protection against heterologous viral infection in BALBIe mice", Clin Vaccine Immunol., (20130800), vol. 20, no. 8, doi:10.1128/CVI.00145-13, pages 1246 - 54, XP055290048

DOI:   http://dx.doi.org/10.1128/CVI.00145-13
    - ZHANG YWEI YZHANG XCAI HNIEWIESK SLI J, "Rational design of human metapneumovirus live attenuated vaccine candidates by inhibiting viral mRNA cap methyltransferase", J Virol., (20141000), vol. 88, no. 19, pages 11411 - 29
    - BIACCHESI SSKIADOPOULOS MHTRAN KCMURPHY BRCOLLINS PLBUCHHOLZ UJ, "Recovery of human metapneumovirus from cDNA: optimization of growth in vitro and expression of additional genes", Virology, (20040000), vol. 321, no. 2, doi:10.1016/j.virol.2003.12.020, pages 247 - 59, XP004499206

DOI:   http://dx.doi.org/10.1016/j.virol.2003.12.020
    - BIACCHESI SPHAM QNSKIADOPOULOS MHMURPHY BRCOLLINS PLBUCHHOLZ UJ, "Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidates", Journal of virology, (20050000), vol. 79, no. 19, doi:10.1128/JVI.79.19.12608-12613.2005, pages 12608 - 13, XP002790247

DOI:   http://dx.doi.org/10.1128/JVI.79.19.12608-12613.2005
    - BUCHHOLZ UJBIACCHESI SPHAM QNTRAN KCYANG LLUONGO CLSKIADOPOULOS MHMURPHY BRCOLLINS PL, "Deletion of M2 gene open reading frames 1 and 2 of human metapneumovirus: effects on RNA synthesis, attenuation, and immunogenicity", J Virol., (20050600), vol. 79, no. 11, pages 6588 - 97
    - SCHICKLI JHKAUR JMACPHAIL MGUZZETTA JMSPAETE RRTANG RS, "Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters", Virol J., (20080603), vol. 5, page 69, XP021038374
    - PHAM QNBIACCHESI SSKIADOPOULOS MHMURPHY BRCOLLINS PLBUCHHOLZ UJ, "Chimeric recombinant human metapneumoviruses with the nucleoprotein or phosphoprotein open reading frame replaced by that of avian metapneumovirus exhibit improved growth in vitro and atténuation in vivo", J Virol., (20051200), vol. 79, no. 24, doi:10.1128/JVI.79.24.15114-15122.2005, pages 15114 - 22, XP055273516

DOI:   http://dx.doi.org/10.1128/JVI.79.24.15114-15122.2005
    - KARRON RASAN MATEO JWANIONEK KCOLLINS PLBUCHHOLZ UJ, "Evaluation of a Live Attenuated Human Metapneumovirus Vaccine in Adults and Children", J Pediatric. Infect Dis Soc., (20180219), vol. 7, no. 1, pages 86 - 89
    - TANG RSSCHICKLI JHMACPHAIL MFERNANDES FBICHA LSPAETE JFOUCHIER RAOSTERHAUS ADSPAETE RHALLER AA, "Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3' proximal genome positions of bovinelhuman parainfluenza virus type 3 on virus replication and immunogenicity", J Virol., (20031000), vol. 77, no. 20, doi:10.1128/JVI.77.20.10819-10828.2003, pages 10819 - 28, XP002318487

DOI:   http://dx.doi.org/10.1128/JVI.77.20.10819-10828.2003
    - TANG RSMAHMOOD KMACPHAIL MGUZZETTA JMHALLER AALIU HKAUR JLAWLOR HASTILLMAN EASCHICKLI JH, "A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus(hMPV) fusion protein elicits protective immunity in African green monkeys", Vaccine, (20050225), vol. 23, no. 14, doi:10.1016/j.vaccine.2004.10.009, pages 1657 - 67, XP004739797

DOI:   http://dx.doi.org/10.1016/j.vaccine.2004.10.009
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DOI:   http://dx.doi.org/10.1016/j.virol.2017.05.021
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DOI:   http://dx.doi.org/10.1006/viro.2001.1138
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DOI:   http://dx.doi.org/10.1099/jgv.0.000796
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 FR20180056801
 WO2019FR51759
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