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Extract from the Register of European Patents

EP About this file: EP3856169

EP3856169 - METHODS OF TREATING MYELOPROLIFERATIVE DISORDERS [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  02.07.2021
Database last updated on 14.06.2024
FormerThe international publication has been made
Status updated on  05.04.2020
Most recent event   Tooltip25.08.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Impact Biomedicines, Inc.
86 Morris Avenue
Summit, New Jersey 07901 / US
[2021/31]
Inventor(s)01 / BERRY, Tymara
22 Bradwahl Drive
Morristown, New Jersey 07960 / US
02 / HOOD, John
100 Stratford Court
Del Mar, California 92014 / US
03 / JAMIESON, Catriona
7400 Hillside Drive
La Jolla, California 92037 / US
04 / SCRIBNER, Curtis L.
4287 Howe Street
Oakland, California 94611 / US
 [2021/31]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2021/31]
Application number, filing date19866319.724.09.2019
[2021/31]
WO2019US52608
Priority number, dateUS201862736369P25.09.2018         Original published format: US 201862736369 P
US201862783076P20.12.2018         Original published format: US 201862783076 P
[2021/31]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020068755
Date:02.04.2020
Language:EN
[2020/14]
Type: A1 Application with search report 
No.:EP3856169
Date:04.08.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 02.04.2020 takes the place of the publication of the European patent application.
[2021/31]
Search report(s)International search report - published on:US02.04.2020
(Supplementary) European search report - dispatched on:EP27.05.2022
ClassificationIPC:A61K31/198, A61K31/715, A61K33/14, A61K31/51, A61K31/635, A61K31/675, A61K33/06, A61P35/02, A61K9/00
[2022/26]
CPC:
A61K31/635 (EP,IL); A61K31/506 (KR); A61K31/51 (EP,IL,KR,US);
A61K31/675 (EP,IL,US); A61K33/06 (EP,IL); A61P35/02 (EP,IL,KR,US);
A61K2300/00 (IL,KR) (-)
C-Set:
A61K31/51, A61K2300/00 (EP);
A61K31/635, A61K2300/00 (EP);
A61K31/675, A61K2300/00 (EP);
A61K33/06, A61K2300/00 (EP)
Former IPC [2021/31]A61K31/198, A61K31/715, A61K33/14
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/31]
Extension statesBA23.04.2021
ME23.04.2021
Validation statesKH23.04.2021
MA23.04.2021
MD23.04.2021
TN23.04.2021
TitleGerman:VERFAHREN ZUR BEHANDLUNG VON MYELOPROLIFERATIVEN ERKRANKUNGEN[2021/31]
English:METHODS OF TREATING MYELOPROLIFERATIVE DISORDERS[2021/31]
French:PROCÉDÉS DE TRAITEMENT DE TROUBLES MYÉLOPROLIFÉRATIFS[2021/31]
Entry into regional phase23.04.2021National basic fee paid 
23.04.2021Search fee paid 
23.04.2021Designation fee(s) paid 
23.04.2021Examination fee paid 
Examination procedure23.04.2021Examination requested  [2021/31]
19.12.2022Amendment by applicant (claims and/or description)
Fees paidRenewal fee
15.09.2021Renewal fee patent year 03
11.08.2022Renewal fee patent year 04
24.08.2023Renewal fee patent year 05
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Documents cited:Search[A]  - ZHANG QIANG ET AL, "The Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke's Encephalopathy", DRUG METABOLISM AND DISPOSITION, US, vol. 42, no. 10, doi:10.1124/dmd.114.058883, ISSN 0090-9556, (20141027), pages 1656 - 1662, URL: http://dx.doi.org/10.1124/dmd.114.058883, XP055920013 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1124/dmd.114.058883
 [T]  - TALPAZ MOSHE ET AL, "Fedratinib, a newly approved treatment for patients with myeloproliferative neoplasm-associated myelofibrosis", LEUKEMIA, (20200709), vol. 35, no. 1, doi:10.1038/S41375-020-0954-2, ISSN 0887-6924, pages 1 - 17, XP037330089 [T] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1038/s41375-020-0954-2
 [T]  - MULLALLY ANN ET AL, "Fedratinib in myelofibrosis", BLOOD ADVANCES, vol. 4, no. 8, doi:10.1182/bloodadvances.2019000954, ISSN 2473-9529, (20200428), pages 1792 - 1800, URL: http://ashpublications.org/bloodadvances/article-pdf/4/8/1792/1749506/advancesadv2019000954c.pdf, XP055919959 [T] 1-15 * page 1795, column second - page 1796, column first *

DOI:   http://dx.doi.org/10.1182/bloodadvances.2019000954
 [A]  - M. M. GIACOMINI ET AL, "Interaction of 2,4-Diaminopyrimidine-Containing Drugs Including Fedratinib and Trimethoprim with Thiamine Transporters", DRUG METABOLISM AND DISPOSITION, US, (20161216), vol. 45, no. 1, doi:10.1124/dmd.116.073338, ISSN 0090-9556, pages 76 - 85, XP055444055 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1124/dmd.116.073338
International search[A]US2007191405  (NORONHA GLENN [US], et al) [A] 1-4, 6-7, 9-23, 35-40 * ; entire document *;
 [Y]US2013102624  (SCHLOSS JOHN V [US]) [Y] 7, 9-23 * ; para[0030] *;
 [Y]US2013243853  (JAYAN ARVIND [US], et al) [Y] 1-4, 6 * ; Abstract para[0003] *;
 [A]US2016332993  (BRADNER JAMES E [US], et al) [A] 1-4, 6-7, 9-23, 35-40* ; entire document *;
 [XY]  - PARDANANI et al., "Safety and Efficacy of Fedratinib in Patients With Primary or Secondary Myelofibrosis", JAMA Oncology, (20150618), vol. 1, pages 643 - 651, XP055701880 [X] 35-39 [Y] 40

DOI:   http://dx.doi.org/10.1001/jamaoncol.2015.1590
 [Y]  - CURTO-GARCIA et al., "Thiamine deficiency appears uncommon in patients with Myeloproliferative Neoplasms", British Journal of Haematology, (20160502), vol. 178, pages 338 - 340, XP055701883 [Y] 1-4, 6-7, 9-23, 40

DOI:   http://dx.doi.org/10.1111/bjh.14128
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