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Extract from the Register of European Patents

EP About this file: EP3865129

EP3865129 - TRPV4 ACTIVITY INHIBITOR [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  16.07.2021
Database last updated on 31.08.2024
FormerThe international publication has been made
Status updated on  18.04.2020
Most recent event   Tooltip23.10.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Kao Corporation
14-10, Nihonbashi-Kayabacho 1-chome
Chuo-ku
Tokyo 103-8210 / JP
[2021/33]
Inventor(s)01 / IWASHITA, Masazumi
c/o Kao Corporation Research Laboratories, 2606
Akabane, Ichikai-machi
Haga-gun, Tochigi 321-3497 / JP
02 / KITAMURA, Naoya
c/o Kao Corporation Research Laboratories, 2606
Akabane, Ichikai-machi
Haga-gun, Tochigi 321-3497 / JP
 [2021/33]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstraße 3
81675 München / DE
[2021/33]
Application number, filing date19871061.809.10.2019
[2021/33]
WO2019JP39851
Priority number, dateJP2018019198010.10.2018         Original published format: JP 2018191980
[2021/33]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020075764
Date:16.04.2020
Language:JA
[2020/16]
Type: A1 Application with search report 
No.:EP3865129
Date:18.08.2021
Language:EN
[2021/33]
Search report(s)International search report - published on:JP16.04.2020
(Supplementary) European search report - dispatched on:EP12.07.2022
ClassificationIPC:C07C69/732, A23L33/10, A61K31/216, A61P1/12, A61P13/10, A61P43/00, C07C69/736, C07K14/47
[2022/32]
CPC:
A23L33/105 (EP); A61K31/222 (EP,US); A23L33/10 (EP,US);
A61K31/216 (EP); A61K9/0053 (US); A61P1/12 (EP);
A61P13/10 (EP); A61P43/00 (EP); C07C69/732 (EP);
C07C69/736 (EP) (-)
Former IPC [2021/33]A61K31/222, A23L33/10, A61P1/00, A61P13/10, A61P43/00, C07C69/732, C07C69/736
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/33]
TitleGerman:HEMMER DER TRPV4-AKTIVITÄT[2021/33]
English:TRPV4 ACTIVITY INHIBITOR[2021/33]
French:INHIBITEUR DE L'ACTIVITÉ DE TRPV4[2021/33]
Entry into regional phase09.04.2021Translation filed 
05.05.2021National basic fee paid 
05.05.2021Search fee paid 
05.05.2021Designation fee(s) paid 
05.05.2021Examination fee paid 
Examination procedure05.05.2021Examination requested  [2021/33]
06.10.2022Amendment by applicant (claims and/or description)
Fees paidRenewal fee
20.10.2021Renewal fee patent year 03
24.10.2022Renewal fee patent year 04
23.10.2023Renewal fee patent year 05
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Documents cited:Search[A]JP2005272362  (MEIJI SEIKA KAISHA) [A] 1,2,4,5 * paragraphs [0006] , [0007] , [0021] , [0022]; claims 4,5,7,8 *;
 [A]US2008031980  (RODRIGUEZ AL [US], et al) [A] 1,2,4,5 * paragraphs [0001] , [0011] , [0012] , [0033]; claims 1,2,18 *;
 [X]CN101962323  (UNIV PLA 2ND MILITARY MEDICAL, et al) [X] 1,4 * page 9, paragraph 91; claims 1-3 *;
 [A]WO2016122889  (KALEIDO BIOSCIENCES INC [US]) [A] 1,3,4,6 * page 198; claim 65; table 5 * * pages 75-76 *;
 [A]JP2017052747  (KAO CORP) [A] 1,2,4,5 * paragraphs [0018] , [0044] , [0045]; claims 1,2 *;
 [X]  - YUAN ET AL, "Synthesis of derivatives of methyl rosmarinate and their inhibitory activities against matrix metalloproteinase-1(MMP-1)", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, (20130101), vol. 62, doi:10.1016/j.ejmech.2012.09.047, pages 148 - 157, XP055704413 [X] 1,4 * page 151; table 2; compound 10L * * page 150, column r, lines 1-5, paragraph 2 - page 152, column l, lines 1-11 * * page 153, column r, paragraph 4 *

DOI:   http://dx.doi.org/10.1016/j.ejmech.2012.09.047
 [A]  - AL-QUDAH MAHMOUD A. ET AL, "Flavonoid and phenolic compounds from Salvia palaestina L. growing wild in Jordan and their antioxidant activities", Amsterdam , NL, vol. 99, doi:10.1016/j.phytochem.2014.01.001, ISSN 0031-9422, (20140301), pages 115 - 120, PHYTOCHEMISTRY, URL: https://www.sciencedirect.com/science/article/pii/S0031942214000041/pdfft?md5=95c8890eca0a0d5ecbcb76e76a280d49&pid=1-s2.0-S0031942214000041-main.pdf, XP055888888 [A] 1,4 * page 116, column l, paragraph 2; figure 1; compounds 3,7 *

DOI:   http://dx.doi.org/10.1016/j.phytochem.2014.01.001
 [A]  - ZENG BIAO ET AL, "and Their Inhibitory Effects on [alpha] -Glucosidase and Vascular Endothelial Cells Injury", CHEMISTRY & BIODIVERSITY, CH, (20160501), vol. 13, no. 5, doi:10.1002/cbdv.201500187, ISSN 1612-1872, pages 596 - 601, XP055888867 [A] 1,4 * abstract *

DOI:   http://dx.doi.org/10.1002/cbdv.201500187
 [A]  - ALLAM SHADY ET AL, "Extracts from peppermint leaves, lemon balm leaves and in particular angelica roots mimic the pro-secretory action of the herbal preparation STW 5 in the human intestine", PHYTOMEDICINE, AMSTERDAM, NL, (20151101), vol. 22, no. 12, doi:10.1016/j.phymed.2015.08.008, ISSN 0944-7113, pages 1063 - 1070, XP055889298 [A] 1,3,4,6 * abstract * * pages 1065,-69 * * page 1070, column l, paragraph 3 *

DOI:   http://dx.doi.org/10.1016/j.phymed.2015.08.008
 [A]  - MCKAY ET AL, "A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.)", PHYSIOTHERAPY RESEARCH, JOHN WILEY & SONS LTD. CHICHESTER, GB, (20060801), vol. 20, no. 8, doi:10.1002/PTR.1936, ISSN 0951-418X, pages 619 - 633, XP009145205 [A] 1,3,4,6 * the whole document *

DOI:   http://dx.doi.org/10.1002/ptr.1936
International search[YA]JP2003521511  (GLAXO GROUP LTD.) [Y] 3, 6, 10, 13, 19, 22 * , claims, paragraph [0004] & US 2003/0013717 A1, claims, paragraph [0005] & WO 2001/056555 A2 *[A] 1, 2, 4, 5, 7-9, 11, 12, 14-18, 20, 21;
 [YA]JP2005526040  (PHARMACIA CORPORATION) [Y] 2, 5, 9, 12, 18, 21 * , claims, paragraphs [0005], [0006], [0009], [0090] & US 2003/0191172 A1, claims, paragraphs [0007], [0006] , [0010] , [0093] & WO 2003/070233 A1 & EP 1915992 A1 & CA 2475374 A & CN 1633283 A & KR 10-2005-0005410 A * [A] 1, 3, 4, 6-8, 10, 11, 13-17, 19, 20, 22;
 [XYA]JP2005272362  (MEIJI SEIKA KAISHA) [X] 7, 14-16 * , claims (Family: none) * [Y] 2, 3, 5, 6, 9, 10, 12, 13, 18, 19, 21, 22 [A] 1, 4, 8, 11, 17, 20;
 [PX]JP2018177738  (KAO CORP) [PX] 1-22 * , claims (Family: none) *;
 [XA]  - YUAN, H. et al., "Synthesis of derivatives of methyl rosmarinate and their inhibitory activities against matrix metalloproteinase-1(MMP-1)", European Journal of Medicinal Chemistry, (20130000), vol. 62, ISSN 0223-5234, pages 148 - 157, XP055704413 [X] 14-16 * , abstract, tab. 2, compound 10L * [A] 1-13, 17-22

DOI:   http://dx.doi.org/10.1016/j.ejmech.2012.09.047
by applicantJP2005272362
 JP2014024809
    - TIAN W., Am. J. Physiol. Renal. Physiol., (20040000), vol. 287, pages F17 - F24
    - NILIUS B., Physiol. Rev., (20070000), vol. 87, pages 165 - 217
    - GEVAERT T., J. Clin. Invest., (20070000), vol. 117, pages 3453 - 3462
    - NICOLAS CENAC et al., Gastroenterology, (20150000), vol. 149, pages 433 - 444
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.