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Extract from the Register of European Patents

EP About this file: EP3880241

EP3880241 - AUXOTROPHIC STRAINS OF STAPHYLOCOCCUS BACTERIUM [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  20.08.2021
Database last updated on 11.09.2024
FormerThe international publication has been made
Status updated on  22.05.2020
Most recent event   Tooltip27.11.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
AZITRA, INC.
21 Business Park Drive
Branford, CT 06405 / US
[2021/38]
Inventor(s)01 / ANDREWS, Richard
400 Farmington Avenue, CB126
Farmington, CT 06032 / US
 [2021/38]
Representative(s)Marks & Clerk LLP
15 Fetter Lane
London EC4A 1BW / GB
[N/P]
Former [2021/38]Chapman, Paul Gilmour
Marks & Clerk LLP
40 Torphichen Street
Edinburgh EH3 8JB / GB
Application number, filing date19885205.514.11.2019
[2021/38]
WO2019US61439
Priority number, dateUS201862768485P16.11.2018         Original published format: US 201862768485 P
[2021/38]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020102507
Date:22.05.2020
Language:EN
[2020/21]
Type: A1 Application with search report 
No.:EP3880241
Date:22.09.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 22.05.2020 takes the place of the publication of the European patent application.
[2021/38]
Search report(s)International search report - published on:US22.05.2020
(Supplementary) European search report - dispatched on:EP15.07.2022
ClassificationIPC:A61K39/085, C12N15/74, C12N1/12, C12N1/20, C12N15/00, C12Q1/68, A61P35/00
[2021/38]
CPC:
C12N9/90 (EP,IL,KR,US); C12N15/74 (EP,IL,KR,US); A61K35/74 (US);
A61K39/085 (EP,IL,KR); A61P35/00 (EP,IL,KR); C12N1/205 (EP,IL);
C12N9/1096 (EP,IL,KR,US); C12Q1/689 (KR); C12Y206/01021 (EP,IL,KR,US);
C12Y501/01001 (EP,IL,KR,US); C12R2001/45 (EP,IL) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/38]
TitleGerman:AUXOTROPHE STÄMME VON STAPHYLOCOCCUS-BAKTERIEN[2021/38]
English:AUXOTROPHIC STRAINS OF STAPHYLOCOCCUS BACTERIUM[2021/38]
French:SOUCHES AUXOTROPHES DE BACTÉRIE STAPHYLOCOCCUS[2021/38]
Entry into regional phase16.04.2021National basic fee paid 
16.04.2021Search fee paid 
16.04.2021Designation fee(s) paid 
16.04.2021Examination fee paid 
Examination procedure16.04.2021Examination requested  [2021/38]
10.02.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
29.11.2021Renewal fee patent year 03
28.11.2022Renewal fee patent year 04
27.11.2023Renewal fee patent year 05
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Documents cited:Search[A]WO2015184134  (AZITRA [US]) [A] 11-15 * abstract; page 10 last par.; claims 1-43 *;
 [XP]WO2019136207  (AZITRA INC [US]) [XP] 1-10 * Claims 1-4, 8-11, 14, 15 *;
 [XI]  - MIRIAM MOSCOSO ET AL, "A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus", VIRULENCE, US, (20180227), vol. 9, no. 1, doi:10.1080/21505594.2017.1417723, ISSN 2150-5594, pages 604 - 620, XP055619262 [X] 1,2,9 * abstract; page 607, col. 1 par. 1, Fig.3; page 616, col. 1 par. 2 * [I] 3-8,10-15

DOI:   http://dx.doi.org/10.1080/21505594.2017.1417723
 [A]  - Eilers R. E. ET AL, "Dermatologic Infections in Cancer Patients Treated With Epidermal Growth Factor Receptor Inhibitor Therapy", JNCI : Journal of the National Cancer Institute, United States, doi:10.1093/jnci/djp439, (20100106), pages 47 - 53, URL: https://watermark.silverchair.com/djp439.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtQwggLQBgkqhkiG9w0BBwagggLBMIICvQIBADCCArYGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMjdPblHjADcj-5dvsAgEQgIICh1BYYEWom66oC64gemzXuZcMoVaHB4SU23SZqETk9z1_6E_FLyLWfLWLU56XkR2sCdE1uOOHzSliN8gOzlOa2Wb-j4uS-, (20220704), XP055938167 [A] 11-15 * abstract; page 48, col.1, penultimate paragraph and col. 2, paragraphs 2 and 3; Table 2 *

DOI:   http://dx.doi.org/10.1093/jnci/djp439
 [T]  - SCHMIDT CHARLIE, "Out of your skin", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP US, NEW YORK, vol. 38, no. 4, doi:10.1038/S41587-020-0473-8, ISSN 1087-0156, (20200317), pages 392 - 397, (20200317), XP037086866 [T] 1-15

DOI:   http://dx.doi.org/10.1038/s41587-020-0473-8
International search[Y]US2007110748  (HOOK MAGNUS [US], et al) [Y] 3, 10/(1-3) * , Abstract, para [0003], [0046], [0066], [0110], [0259], and [0310] *;
 [Y]US2010150956  (PATTI JOSEPH M [US], et al) [Y] 3, 10/(1-3) * , Abstract, para [0004], [0069], and [0140] *;
 [Y]US2016235834  (BOU ARÉVALO GERMÁN [ES], et al) [Y] 4, 10/(4) * , Abstract, para [0014], [0017], [0035], [0115], [0148], [0159], [0183], [0210], and [0373] *;
 [XY]  - MOSCOSO et al., "A D-Alanine auxotrophic live vaccine is effective against lethal infection caused by Staphylococcus aureus", Virulence, (20180101), vol. 9, no. 1, doi:10.1080/21505594.2017.1417723, pages 604 - 620, XP055619262 [X] 1-2 * . Abstract; pg 605, col 1, last para, col 2, up para, and Fig 1; pg 607, col 1, top para and para 2; pg 608, col 2, lower para; pg 610, col 1, last para; pg 611, Fig 6; pg 612, Fig 7; pg 618, col 1, para 3; and pg 619, col 2, Ref. 43 * [Y] 3-4, 10

DOI:   http://dx.doi.org/10.1080/21505594.2017.1417723
 [A]  - ZHANG et al., "Inactivation of glutamate racemase (Murl) eliminates virulence in Streptococcus mutans", Microbiol Res., (20160000), vol. 186 - 18, pages 1 - 8, XP029557127 [A] 1-4, 10 * . Abstract; pg 2, col 1, last para; pg 3, col 2, middle para; and pg 7, col 2, para 2 *

DOI:   http://dx.doi.org/10.1016/j.micres.2016.02.003
 [A]  - WEI et al., "Alanine racemase is essential for the growth and interspecies competitiveness of . Streptococcus mutans", Int J Oral Sci., (20160000), vol. 8, no. 4, doi:10.1038/ijos.2016.34, pages 231 - 238, XP055619268 [A] 1-4, 10 * . Entire documentation, especially Abstract *

DOI:   http://dx.doi.org/10.1038/ijos.2016.34
 [A]  - SHAHROOEI et al., "Vaccination with SesC Decreases Staphylococcus epidermidis Biofilm Formation", Infect Immun., (20120000), vol. 80, no. 10, doi:10.1128/IAI.00104-12, pages 3660 - 8, XP055095942 [A] 1-4, 10 * . Entire documentation, especially Abstract *

DOI:   http://dx.doi.org/10.1128/IAI.00104-12
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