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Extract from the Register of European Patents

EP About this file: EP3897634

EP3897634 - COMPOUNDS FOR THE REDUCTION OF THE DELETERIOUS ACTIVITY OF EXTENDED NUCLEOTIDE REPEAT CONTAINING GENES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  21.07.2023
Database last updated on 30.09.2024
FormerRequest for examination was made
Status updated on  24.09.2021
FormerThe international publication has been made
Status updated on  02.07.2020
Most recent event   Tooltip21.07.2023Application deemed to be withdrawnpublished on 23.08.2023  [2023/34]
Applicant(s)For all designated states
The Board of Trustees of the Leland Stanford Junior University
Office of the General Counsel
Building 170, Third Floor, Main Quad
P.O. Box 20386
Stanford, CA 94305-2038 / US
For all designated states
National Yang Ming Chiao Tung University
No. 155, Sec. 2, Linong St.
Beitou Dist.
Taipei City 112 / TW
[2021/43]
Inventor(s)01 / SUN, Thomas W.
1455 Adams Drive, Suite 1120
Menlo Park, California 94025 / US
02 / PROBST, Gary
1455 Adams Drive, Suite 1120
Menlo Park, California 94025 / US
03 / BAIK, Jason
1455 Adams Drive, Suite 1120
Menlo Park, California 94025 / US
 [2021/43]
Representative(s)Bals & Vogel Patentanwälte PartGmbB
Konrad-Zuse-Str. 4
44801 Bochum / DE
[N/P]
Former [2021/43]Patentanwälte Bals & Vogel
Universitätsstrasse 142
44799 Bochum / DE
Application number, filing date19898813.112.12.2019
[2021/43]
WO2019US66022
Priority number, dateUS201862781469P18.12.2018         Original published format: US 201862781469 P
[2021/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020131573
Date:25.06.2020
Language:EN
[2020/26]
Type: A1 Application with search report 
No.:EP3897634
Date:27.10.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 25.06.2020 takes the place of the publication of the European patent application.
[2021/43]
Search report(s)International search report - published on:US25.06.2020
(Supplementary) European search report - dispatched on:EP19.08.2022
ClassificationIPC:C07D209/88, C07D401/12, C07D403/04, C07D403/12, C07D409/12, C07D471/04, C07F5/04, C07F5/05, A61K31/4439, A61P25/28
[2022/38]
CPC:
A61K45/06 (EP,IL); A61K31/404 (EP,IL,US); A61K31/4155 (US);
A61K31/437 (US); A61K31/4439 (EP,IL,US); A61K31/496 (EP,IL,US);
A61K31/5377 (EP,IL,US); A61K31/69 (EP,IL,US); A61P25/28 (EP,IL,US);
C07B59/001 (EP,IL); C07D209/88 (EP,IL,US); C07D401/12 (EP,IL,US);
C07D403/04 (EP,IL,US); C07D403/12 (EP,IL); C07D409/12 (EP,IL,US);
C07D471/04 (EP,IL,US); C07F5/025 (EP,IL,US); A61K2300/00 (IL);
C07B2200/05 (US) (-)
C-Set:
A61K31/404, A61K2300/00 (EP);
A61K31/4439, A61K2300/00 (EP);
A61K31/496, A61K2300/00 (EP);
A61K31/5377, A61K2300/00 (EP);
A61K31/69, A61K2300/00 (EP)
(-)
Former IPC [2021/43]A61K31/4439
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/43]
TitleGerman:VERBINDUNGEN ZUR REDUKTION DER SCHÄDLICHEN AKTIVITÄT VON GENEN MIT VERLÄNGERTEN NUKLEOTIDREPEAT-HALTIGEN GENEN[2021/43]
English:COMPOUNDS FOR THE REDUCTION OF THE DELETERIOUS ACTIVITY OF EXTENDED NUCLEOTIDE REPEAT CONTAINING GENES[2021/43]
French:COMPOSÉS POUR LA RÉDUCTION DE L'ACTIVITÉ DÉLÉTÈRE DE GÈNES CONTENANT UNE RÉPÉTITION DE NUCLÉOTIDES ÉTENDUE[2021/43]
Entry into regional phase25.06.2021National basic fee paid 
25.06.2021Search fee paid 
25.06.2021Designation fee(s) paid 
25.06.2021Examination fee paid 
Examination procedure25.06.2021Examination requested  [2021/43]
17.03.2023Application deemed to be withdrawn, date of legal effect  [2023/34]
06.04.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2023/34]
Fees paidRenewal fee
08.12.2021Renewal fee patent year 03
04.12.2022Renewal fee patent year 04
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Documents cited:Search[X]WO2005023245  (SMITHKLINE BEECHAM CORP [US], et al) [X] 1-3,5 * Abstract; claim 1; examples 15, 16, 18, 23, 25, 29, 30, 31A, 31B, 32-36, 42-49, 51-59, 61, 62, 64, 71. *;
 [X]WO2005037791  (CHIRON CORP [US], et al) [X] 1-3,5,6,8* Abstract; claims; examples 15, 17, 22, 25-27, 30, 33, 38, 39, 44, 53, 69, 70, 80, 97, 98, 204, 209, 218, 221-223, 228, 266. *;
 [X]WO2016196664  (CEDARS SINAI MEDICAL CENTER [US]) [X] 1-3,5 * Page 19, paragraph 71 to page 21, paragraph 80. *;
 [X]WO2017117006  (UNIV LELAND STANFORD JUNIOR [US]) [X] 1-3,5,6,8,9 * Abstract; claims; pages 15-17, paragraph 68; pages 57, 59, 60: compounds 4, 6, 13. *;
 CN107739371  [ ] (UNIV EAST CHINA NORMAL, et al);
 [X]  - GUDMUNDSSON ET AL., "Substituted tetrahydrocarbazoles with potent activity against human papillomaviruses", BIOORG. MED. CHEM. LETT., vol. 19, no. 13, doi:10.1016/J.BMCL.2009.05.003, ISSN 0960-894X, (20090701), pages 3489 - 3492, (20090507), XP026155093 [X] 1-3,5 * Abstract; page 3490, table 1: compounds 1-17; page 2491, table 2: compounds 4, 22, 9, 26, 27. *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2009.05.003
 [X]  - Chen et al., "Method for preparing tetrahydrocarbazole-type small-molecule organic compound and its application in preparing antimicrobial drug", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, (20180227), Database accession no. 2018:325653, URL: STN, XP055950174 [X] 1-3,5 * abstract *
 [X]  - KIEFER ET AL., "Design and synthesis of calindol derivatives as potent and selective calcium sensing receptor agonists", BIOORG. MED. CHEM., (20151212), vol. 24, no. 4, doi:10.1016/J.BMC.2015.12.019, ISSN 0968-0896, pages 554 - 569, XP029399979 [X] 1-3,5,11 * Page 559, table 3, and the paragraph bridging pages 565 and 566: compound 56 and its hydrochloride. *

DOI:   http://dx.doi.org/10.1016/j.bmc.2015.12.019
International search[A]US2009170923  (GUDMUNDSSON KRISTJAN [US]) [A] 1-3, 12-14 * ; entire document *;
 [Y]WO2013139929  (UNIV MUENCHEN L MAXIMILIANS [DE], et al) [Y] 1-3, 12-14 * ; pg. 31, Table 43, pg. 32, In 16-20, pg. 39, In 33 *;
 [A]US2018127366  (ZHANG CHENGZHI [US], et al) [A] 1-3, 12-14 * ; entire document *;
 [PX]WO2018236910  (UNIV LELAND STANFORD JUNIOR [US], et al) [PX] 1-3, 12-14* ; entire document *;
 [Y]  - CZEREDYS et al., "Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease", Biochemical and Biophysical Research Communications, (20160820), vol. 483, doi:10.1016/j.bbrc.2016.08.106, pages 1194 - 1205, XP029917808 [Y] 1-3, 12-14 * ; pg. 1194, abstract, pg. 1197, Table 1 *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2016.08.106
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