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Extract from the Register of European Patents

EP About this file: EP3898998

EP3898998 - MODIFIED ORTHOPOXVIRUS VECTORS [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  24.09.2021
Database last updated on 28.06.2024
FormerThe international publication has been made
Status updated on  02.07.2020
Most recent event   Tooltip23.10.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Ottawa Hospital Research Institute
501 Smyth Road
Ottawa, Ontario K1H 8L6 / CA
For all designated states
TURNSTONE BIOLOGICS CORP.
920 Broadway, 16th Floor
New York, NY 10010 / US
[2021/43]
Inventor(s)01 / BELL, John C.
248 Knox Crescent
Ottawa, Ontario K1G 0K8 / CA
02 / HUH, Michael S.
577 Ozawa Private
Ottawa, Ontario K1K 4Z9 / CA
03 / TANG, Matthew Y.
5938 Meadowglen Drive
Orleans, Ontario K1C 5Z6 / CA
04 / PELIN, Adrian
1010 16th St, Unit 328
San Francisco, California 94107 / US
05 / BREITBACH, Caroline J.
46 Belmont Street, Unit 2
Somerville, Massachusetts 02143 / US
06 / BURGESS, Michael F.
9 Meadowbrook Road
Chester, New Jersey 07930 / US
07 / BERNSTEIN, Steven H.
2739 Main Street
Lawrenceville, New Jersey 08648 / US
 [2021/43]
Representative(s)Jones Day
Rechtsanwälte, Attorneys-at-Law, Patentanwälte
Prinzregentenstrasse 11
80538 München / DE
[2021/43]
Application number, filing date19899693.620.12.2019
[2021/43]
WO2019CA51898
Priority number, dateUS201862784372P21.12.2018         Original published format: US 201862784372 P
US201962872699P10.07.2019         Original published format: US 201962872699 P
US201962930524P04.11.2019         Original published format: US 201962930524 P
[2021/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020124273
Date:25.06.2020
Language:EN
[2020/26]
Type: A1 Application with search report 
No.:EP3898998
Date:27.10.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 25.06.2020 takes the place of the publication of the European patent application.
[2021/43]
Search report(s)International search report - published on:CA25.06.2020
(Supplementary) European search report - dispatched on:EP06.09.2022
ClassificationIPC:C12N15/863, A61K35/768, A61P35/00, C07K14/065, C07K16/28, C12N15/12, C12N15/13, C12N15/19, C12N15/24, C12N15/39, C12N15/52, C12N5/10, C12N7/01
[2021/43]
CPC:
C07K16/2818 (EP,IL,KR,US); C12N15/86 (EP,IL,KR,US); A61K35/768 (EP,IL,KR,US);
A61K38/00 (KR); A61K39/3955 (EP,IL); A61P35/00 (EP,IL,KR);
C07K14/52 (EP,IL,KR,US); C07K14/5434 (EP,IL,KR,US); C12N7/00 (EP,IL);
A61K2039/505 (EP,IL,KR); A61K2300/00 (IL); C12N2710/24121 (EP,IL,US);
C12N2710/24122 (EP,IL,US); C12N2710/24132 (EP,IL,KR,US); C12N2710/24143 (EP,IL,KR,US) (-)
C-Set:
A61K39/3955, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/43]
TitleGerman:MODIFIZIERTE ORTHOPOXVIRUS-VEKTOREN[2021/43]
English:MODIFIED ORTHOPOXVIRUS VECTORS[2021/43]
French:VECTEURS D'ORTHOPOXVIRUS MODIFIÉS[2021/43]
Entry into regional phase17.06.2021National basic fee paid 
17.06.2021Search fee paid 
17.06.2021Designation fee(s) paid 
17.06.2021Examination fee paid 
Examination procedure17.06.2021Examination requested  [2021/43]
27.03.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
05.10.2021Renewal fee patent year 03
25.10.2022Renewal fee patent year 04
23.10.2023Renewal fee patent year 05
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Documents cited:Search[A]WO2016008976  (TRANSGENE SA [FR]) [A] 1-15* the whole document *;
 [AP]WO2019134048  (BELL JOHN C [CA], et al) [AP] 1-15 * figure 40; example 22; table 2 *;
 [AP]  - Pelin Adrian ET AL, "Bio-Engineering Vaccinia Viruses for Increased Oncolytic Potential", doi:10.20381/ruor-24148, (20191202), URL: https://ruor.uottawa.ca/handle/10393/39909, (20220628), XP055935967 [AP] 1-15 * see chapter 3; pages 101-103; figure 3.16; table 3.2 *

DOI:   http://dx.doi.org/10.20381/ruor-24148
International search[A]  - VERARDI et al., "Vaccinia Virus Vectors with an Inactivated Gamma Interferon Receptor Homolog Gene (B8R) Are Attenuated In Vivo without a Concomitant Reduction in Immunogenicity", Journal of Virology, (20010100), vol. 75, no. 1, doi:10.1128/JVI.75.1.11-18.2001, ISSN 0022-538X, pages 11 - 18, XP002409049

DOI:   http://dx.doi.org/10.1128/JVI.75.1.11-18.2001
 [A]  - CURRAN et al., "Tumor Vaccines Expressing Flt3-Ligand Synergize with CTLA-4 Blockade to Reject Pre-Implanted Tumors", Cancer Research, (20091001), vol. 69, no. 19, ISSN 1538-7445, pages 7747 - 7755, XP055177400

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-08-3289
 [A]  - VOM BERG et al., "Intratumoral IL -12 combined with CTLA-4 blockade elicits T cell mediate, glioma rejection", The Journal of Experimental Medicine, (20130000), vol. 210, no. 13, doi:10.1084/jem.20130678, ISSN 1540-9538, pages 2803 - 2811, XP055513130

DOI:   http://dx.doi.org/10.1084/jem.20130678
 [A]  - DE GRAAF et al., "Armed oncolytic viruses: A kick-start for anti-tumor immunity", Cytokine and Growth Factor Reviews, (20180319), vol. 41, doi:10.1016/j.cytogfr.2018.03.006, ISSN 1359-6101, pages 28 - 39, XP055580278

DOI:   http://dx.doi.org/10.1016/j.cytogfr.2018.03.006
 [A]  - VAN DER JEUGHT et al., "Targeting the tumor microenvironment to enhance antitumor immune responses", Oncotarget, (20141226), vol. 6, no. 3, ISSN 1949-2553, pages 1359 - 1381, XP055351674

DOI:   http://dx.doi.org/10.18632/oncotarget.3204
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.