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Extract from the Register of European Patents

EP About this file: EP3925611

EP3925611 - RADIOSENSITIZER [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  27.04.2024
Database last updated on 02.09.2024
FormerRequest for examination was made
Status updated on  19.11.2021
FormerThe international publication has been made
Status updated on  11.09.2020
Most recent event   Tooltip24.08.2024New entry: Reply to examination report 
Applicant(s)For all designated states
M.T.3, Inc.
3-20-2 Shibaura
Minato-ku
Tokyo
108-0023 / JP
For all designated states
Nihon University
8-24 Kudan-minami 4-Chome
Chiyoda-ku
Tokyo 102-8275 / JP
For all designated states
School Corporation, Azabu Veterinary Medicine Educational Institution
1-17-71, Fuchinobe
Chuo-ku
Sagamihara-shi, Kanagawa 252-5201 / JP
[2021/51]
Inventor(s)01 / SAHARA, Hiroeki
c/o AZABU University, 1-17-71 Fuchinobe, Chuo-ku
Sagamihara-shi, Kanagawa 252-5201 / JP
02 / NAKAYAMA, Tomohiro
c/o NIHON University, 8-24, Kudan-minami 4-chome
Chiyoda-ku
Tokyo 102-8275 / JP
03 / MARUO, Takuya
c/o AZABU University, 1-17-71 Fuchinobe, Chuo-ku
Sagamihara-shi, Kanagawa 252-5201 / JP
[N/P]
Former [2021/51]01 / SAHARA, Hiroeki
Sagamihara-shi, Kanagawa 252-5201 / JP
02 / NAKAYAMA, Tomohiro
Tokyo 102-8275 / JP
03 / MARUO, Takuya
Sagamihara-shi, Kanagawa 252-5201 / JP
Representative(s)Drywood, Rosalind Aerona, et al
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
[2021/51]
Application number, filing date19918427.624.10.2019
[2021/51]
WO2019JP41730
Priority number, dateJP2019003974905.03.2019         Original published format: JP 2019039749
[2021/51]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020179125
Date:10.09.2020
Language:JA
[2020/37]
Type: A1 Application with search report 
No.:EP3925611
Date:22.12.2021
Language:EN
[2021/51]
Search report(s)International search report - published on:JP10.09.2020
(Supplementary) European search report - dispatched on:EP10.03.2022
ClassificationIPC:A61K31/7028, A61K41/00, A61P35/00
[2021/51]
CPC:
A61K41/0038 (EP); A61K31/7032 (US); A61K31/7028 (EP);
A61N5/10 (US); A61P35/00 (EP,US); A61N2005/1098 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/51]
TitleGerman:RADIOSENSIBILISATOR[2021/51]
English:RADIOSENSITIZER[2021/51]
French:RADIOSENSIBILISATEUR[2021/51]
Entry into regional phase14.09.2021Translation filed 
14.09.2021National basic fee paid 
14.09.2021Search fee paid 
14.09.2021Designation fee(s) paid 
14.09.2021Examination fee paid 
Examination procedure14.09.2021Examination requested  [2021/51]
28.09.2022Amendment by applicant (claims and/or description)
30.04.2024Despatch of a communication from the examining division (Time limit: M04)
23.08.2024Reply to a communication from the examining division
Fees paidRenewal fee
14.09.2021Renewal fee patent year 03
19.10.2022Renewal fee patent year 04
25.10.2023Renewal fee patent year 05
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Documents cited:Search[XY]EP2130834  (TOYO SUISAN KAISHA [JP]) [X] 1-4,8,9 * claim 1 * * paragraph [0108] * [Y] 1-9;
 [XY]  - YOICHI TAKAKUSAGI ET AL, "A Multimodal Molecular Imaging Study Evaluates Pharmacological Alteration of the Tumor Microenvironment to Improve Radiation Response", CANCER RESEARCH, US, (20181215), vol. 78, no. 24, doi:10.1158/0008-5472.CAN-18-1654, ISSN 0008-5472, pages 6828 - 6837, XP055735704 [X] 1-4,8,9 * page 6829, column r, paragraph 1 * [Y] 1-9

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-18-1654
 [XY]  - YUGO SAWADA ET AL, "Sulfoquinovosylacylpropanediol is a novel potent radiosensitizer in prostate cancer", INTERNATIONAL JOURNAL OF UROLOGY, JP, (20150317), vol. 22, no. 6, doi:10.1111/iju.12753, ISSN 0919-8172, pages 590 - 595, XP055735708 [X] 1-4,8,9 * page 590, abstract * * page 591, right-hand column, Treatments * [Y] 1-9

DOI:   http://dx.doi.org/10.1111/iju.12753
 [XY]  - SAKIMOTO IPPEI ET AL, "alpha-sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis", CANCER RESEARCH, (200602), vol. 66, no. 4, ISSN 0008-5472, pages 2287 - 2295, XP002805785 [X] 1-4,8,9 * page 2292, column r * * page 2292, column l * [Y] 1-9

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-05-2209
 [XY]  - OHTA KEISUKE ET AL, "Remodeling of the Tumor Microenvironment by Combined Treatment with a Novel Radiosensitizer, alpha-Sulfoquinovosylmonoacylglycerol (alpha-SQMG) and X-irradiation", ANTICANCER RESEARCH, (201011), vol. 30, no. 11, ISSN 0250-7005, pages 4397 - 4404, XP002805786 [X] 1-4,8,9 * page 4398, left-hand column, Treatments * [Y] 1-9
International search[A]WO2006001374  (TOYO SUISAN KAISHA [JP], et al) [A] 1-10;
 [XA]WO2009014101  (TOYO SUISAN KAISHA [JP], et al) [X] 4-9 [A] 1-3, 10;
 [A]WO2010082634  (TOYO SUISAN KAISHA [JP], et al) [A] 1-10;
 [A]JP2016150905  (UNIV OF SCIENCE TOKYO) [A] 1-10;
 [XA]  - Yoichi Takakusagi, Sarwat Naz, Kaori Takakusagi, Masahiro Ishima, Hiroshi Murata, Keisuke Ohta, Masahiko Miura, Fumio Sugawara, Kengo Sakaguchi, Shun Kishimoto, Jeeva P. Munasinghe, James B. Mitchell and Murali C. Krishna, "A Multimodal Molecular Imaging Study Evaluates Pharmacological Alteration of the Tumor Microenvironment to Improve Radiation Response", Cancer Research, (20181215), vol. 78, no. 24, doi:10.1158/0008-5472.CAN-18-1654, ISSN 0008-5472, pages 6828 - 6837, XP055735704 [X] 4-9 * Abstract, Fig. 1, of SQAP on tumor radiotherapy XR Abstract, Fig. 1, of SQAP on tumor * [A] 1-3, 10

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-18-1654
 [XA]  - Yugo Sawada Kazuya Omoto Naoki Kohei Kengo Sakaguchi Masahiko Miura Kazunari Tanabe, "Sulfoquinovosylacylpropanediol is a novel potent radiosensitizer in prostate cancer", International Journal of Urology, (20150317), vol. 22, no. 6, doi:10.1111/iju.12753, ISSN 0919-8172, pages 590 - 595, XP055735708 [X] 4-9 * Abstract, Fig. 2 Abstract, Fig. 2 * [A] 1-3, 10

DOI:   http://dx.doi.org/10.1111/iju.12753
 [XA]  - Jesus Izaguirre-Carbonell, Hirofumi Kawakubo, Hiroshi Murata, Atsushi Tanabe, Toshifumi Takeuchi, Tomoe Kusayanagi, Senko Tsukuda, Takeshi Hirakawa, Kazuki Iwabata, Yoshihiro Kanai, Keisuke Ohta, Masahiko Miura, Kengo Sakaguchi, Sachihiro Matsunaga, Hiroeki Sahara, Shinji Kamisuki , Fumio Sugawara, "Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity", Scientific Reports, (20151012), vol. 5, no. 1, doi:10.1038/srep15136, ISSN 2045-2322, pages 1 - 13, XP055735711 [X] 4, 5-9 * Supplementary Fig. S1 Supplementary Fig. S1 * [A] 1-3, 10

DOI:   http://dx.doi.org/10.1038/srep15136
 [A]  - Hideki Iwamoto, Nakamura Toru, Koga Hironori, Izaguirre-Carbonell Jesus, Kamisuki Shinji, Sugawara Fumio, Abe Mitsuhiko, Iwabata Kazuki, Ikezono Yu, Sakaue Takahiko, Masuda Atsutaka, Yano Hirohisa, Ohta Keisuke, Nakano Masahito, Shimose Shigeo, Shirono Tomotake, Torimura Takuji, "Inhibition of hypoxia-inducible factor via upregulatiuon of von Hippel-Lindau protein induces ''angiogenic switch off'' in a hepatoma mouse mode", Molecular Therapy - Oncolytics, (20150101), vol. 2, doi:10.1038/mto.2015.20, ISSN 2372-7705, pages 1 - 11, XP055735716 [A] 1-10

DOI:   http://dx.doi.org/10.1038/mto.2015.20
by applicantJP2002536341
 JP2007302609
 WO2009014101
 JP2019039749
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.