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Extract from the Register of European Patents

EP About this file: EP4004191

EP4004191 - PRECURSOR CELLS OF INDUCED PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING THE SAME [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  29.04.2022
Database last updated on 19.10.2024
FormerThe international publication has been made
Status updated on  05.02.2021
Most recent event   Tooltip03.10.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Brexogen Inc.
Rm 901, Rm 902, Rm 903, Rm 904
9, Beobwon-ro 8-gil
Songpa-gu
Seoul 05855 / KR
[2022/22]
Inventor(s)01 / KIM, Sue
255-2002
1218, Yangjae-daero
Songpa-gu
Seoul 05649 / KR
 [2022/22]
Representative(s)Plougmann Vingtoft a/s
Strandvejen 70
2900 Hellerup / DK
[2022/22]
Application number, filing date19939428.924.12.2019
[2022/22]
WO2019KR18426
Priority number, dateKR2019009126926.07.2019         Original published format: KR 20190091269
KR2019017307823.12.2019         Original published format: KR 20190173078
[2022/22]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021020666
Date:04.02.2021
Language:EN
[2021/05]
Type: A1 Application with search report 
No.:EP4004191
Date:01.06.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 04.02.2021 takes the place of the publication of the European patent application.
[2022/22]
Search report(s)International search report - published on:KR04.02.2021
(Supplementary) European search report - dispatched on:EP12.09.2022
ClassificationIPC:C12N5/0775
[2022/22]
CPC:
C12N5/0668 (EP); C12N5/0665 (US); C12N5/0662 (EP,US);
C12N5/0696 (EP); C12P1/00 (US); C12N2500/00 (US);
C12N2500/84 (EP,US); C12N2501/115 (EP,US); C12N2506/45 (EP,US);
C12N2510/00 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/22]
TitleGerman:VORLÄUFERZELLEN VON AUS INDUZIERTEN PLURIPOTENTEN STAMMZELLEN ABGELEITETEN MESENCHYMALEN STAMMZELLEN UND VERFAHREN ZUR HERSTELLUNG DERSELBEN[2022/22]
English:PRECURSOR CELLS OF INDUCED PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING THE SAME[2022/22]
French:CELLULES PRÉCURSEURS DE CELLULES SOUCHES MÉSENCHYMATEUSES DÉRIVÉES DE CELLULES SOUCHES PLURIPOTENTES INDUITES ET LEUR PROCÉDÉ DE PRÉPARATION[2022/22]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase13.12.2021National basic fee paid 
13.12.2021Search fee paid 
13.12.2021Designation fee(s) paid 
13.12.2021Examination fee paid 
Examination procedure13.12.2021Examination requested  [2022/22]
11.04.2023Amendment by applicant (claims and/or description)
11.04.2023Date on which the examining division has become responsible
Fees paidRenewal fee
13.12.2021Renewal fee patent year 03
04.10.2022Renewal fee patent year 04
03.10.2023Renewal fee patent year 05
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See the Register of the Unified Patent Court for opt-out data
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Documents cited:Search[A]US2019117701  (IKEYAMA YOSHIFUMI [JP], et al) [A] 1-10 * paragraph [0074] - paragraph [0076]; figure 2 * * paragraph [0081] * * paragraph [0092] - paragraph [0094] * * paragraph [0200] *;
 [XAI]WO2019135645  (ASAN FOUND [KR], et al) [X] 1,5 * paragraph [0136] - paragraph [0139]; example 2 * * paragraph [0126] - paragraph [0127]; example 1 * [A] 2,3,6-10 [I] 4;
 [T]US2021060081  (KIM SUE [KR], et al) [T] * paragraph [0106]; example 1 * * paragraph [0114] - paragraph [0116]; example 2 *;
    [XAYI] - KIM SOO ET AL, "Exosomes Secreted from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Accelerate Skin Cell Proliferation", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 19, no. 10, doi:10.3390/ijms19103119, (20181011), pages 1 - 16, URL: https://www.mdpi.com/1422-0067/19/10/3119, (20220826), XP055782340 [X] 1,2,5,8,9 * page 2, paragraph l - page 3, paragraph 1; figure 1 * * page 10 - page 11 * [A] 3,6,7,10 [Y] 8,9 [I] 4

DOI:   http://dx.doi.org/10.3390/ijms19103119
    [XAYI] - FROBEL JOANA ET AL, "Epigenetic Rejuvenation of Mesenchymal Stromal Cells Derived from Induced Pluripotent Stem Cells & Supplemental data", STEM CELL REPORTS, United States, (20140901), vol. 3, no. 3, doi:10.1016/j.stemcr.2014.07.003, ISSN 2213-6711, pages 414 - 422, XP055955337 [X] 1,3,5 * + supplemantal data *;; figures 2, S2; table S2 * [A] 2,6,7,10 [Y] 8,9 [I] 4

DOI:   http://dx.doi.org/10.1016/j.stemcr.2014.07.003
 [X]  - Frobel Joana ET AL, "Supplemental Information Table S2: Gene expression in iPS-MSCs versus MSCs - Epigenetic Rejuvenation of Mesenchymal Stromal Cells Derived from Induced Pluripotent Stem Cells", Stem Cell Reports, (20140814), URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266008/, (20220826), XP055955405 [X] 3 * Part of Supplement Table S2 relating to comparison iMSC vs MSC *; page 1 *
 [XAI]  - YONGXING LIU ET AL, "One-Step Derivation of Mesenchymal Stem Cell (MSC)-Like Cells from Human Pluripotent Stem Cells on a Fibrillar Collagen Coating", PLOS ONE, (20120301), vol. 7, no. 3, doi:10.1371/journal.pone.0033225, page e33225, XP055240058 [X] 1,5 * page 2, column l, paragraph l - column r, paragraph 3 * * page 3; figure 3 * * page 7, column r * [A] 2,3,6-10 [I] 4

DOI:   http://dx.doi.org/10.1371/journal.pone.0033225
 [A]  - RAQUEL CALLONI ET AL, "Reviewing and Updating the Major Molecular Markers for Stem Cells", STEM CELLS AND DEVELOPMENT, US, (20130501), vol. 22, no. 9, doi:10.1089/scd.2012.0637, ISSN 1547-3287, pages 1455 - 1476, XP055240597 [A] 1-10 * page 1463; table 5 * * page 1464; table 6 *

DOI:   http://dx.doi.org/10.1089/scd.2012.0637
 [A]  - BATTULA V L ET AL, "Human placenta and bone marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation", DIFFERENTIATION, SPRINGER VERLAG, DE, vol. 75, no. 4, doi:10.1111/J.1432-0436.2006.00139.X, ISSN 0301-4681, (20070401), pages 279 - 291, (20070401), XP026765256 [A] 1-10 * page 279 - page 280 * * page 284; figure 1 * * page 286 - page 287; figure 3 *

DOI:   http://dx.doi.org/10.1111/j.1432-0436.2006.00139.x
 [A]  - M. DOMINICI ET AL, "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement", CYTOTHERAPY, GB, (20060101), vol. 8, no. 4, doi:10.1080/14653240600855905, ISSN 1465-3249, pages 315 - 317, XP055570596 [A] 1-5 * page 316; table 1 *

DOI:   http://dx.doi.org/10.1080/14653240600855905
International search[AX]WO2007123363  (CORESTEM CO LTD [KR], et al) [A] 3,4,6,10 [X] 1,2,5,7;
 [A]US2011182866  (MCNIECE IAN K [US])[A] 1-10;
 [A]US2015118198  (SADIQ SAUD A [US], et al) [A] 1-10;
 [A]US2016130556  (HANTASH BASIL M [US]) [A] 1-10;
 [Y]US10080730  (JEFFS ROGER [US], et al) [Y] 8,9;
 [A]US2019017032  (FIRAS JABER [AU], et al) [A] 1-10
by applicantKR20190063453
 KR20190091269
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