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Extract from the Register of European Patents

EP About this file: EP3777834

EP3777834 - SYRINGE [Right-click to bookmark this link]
StatusThe patent has been granted
Status updated on  14.01.2022
Database last updated on 21.03.2026
FormerGrant of patent is intended
Status updated on  03.01.2022
FormerRequest for examination was made
Status updated on  15.01.2021
Most recent event   Tooltip13.03.2026Change - opposition data/opponents data or that of the opponents representativepublished on 15.04.2026 [2026/16]
Applicant(s)For all designated states
Novartis AG
Lichtstrasse 35
4056 Basel / CH
[2021/07]
Inventor(s)01 / BRYANT, Andrew
Novartis Pharma AG
Postfach
4002 Basel / CH
02 / BUETTGEN, Heinrich
Novartis Pharma AG
Postfach
4002 Basel / CH
03 / PAPST, Wolfgang
Novartis Pharma AG
Postfach
4002 Basel / CH
04 / PICCI, Marie
Novartis Pharma AG
Postfach
4002 Basel / CH
 [2021/07]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2022/07]
Former [2021/07]Marshall, Cameron John
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
Application number, filing date20198921.730.05.2013
[2021/07]
Priority number, dateEP2012017062801.06.2012         Original published format: EP 12170628
[2021/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3777834
Date:17.02.2021
Language:EN
[2021/07]
Type: B1 Patent specification 
No.:EP3777834
Date:16.02.2022
Language:EN
[2022/07]
Search report(s)(Supplementary) European search report - dispatched on:EP27.10.2020
ClassificationIPC:A61K9/00, A61M5/28, A61M5/31, A61M5/315, A61P43/00, A61P27/02
[2021/07]
CPC:
A61M5/001 (EP,BR,IL,KR,US); A61M5/28 (EP,BR,IL,KR,US); A61M5/31513 (EP,BR,IL,KR,US);
A61F9/0017 (IL,US); A61F9/00736 (IL,KR); A61M5/3137 (EP,IL,US);
A61M5/31505 (EP,BR,IL,US); A61P27/02 (EP,BR,IL,US); A61P43/00 (EP,BR,IL);
A61M2005/3104 (EP,BR,IL,KR,US); A61M2005/312 (IL,KR); A61M2005/3139 (EP,BR,IL,US);
A61M2005/31508 (EP,BR,IL,US); A61M2210/0612 (IL,KR); Y10T29/49826 (EP,IL,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/07]
Extension statesBA29.09.2020
ME29.09.2020
TitleGerman:SPRITZE[2021/07]
English:SYRINGE[2021/07]
French:SERINGUE[2021/07]
Examination procedure10.11.2020Amendment by applicant (claims and/or description)
10.11.2020Examination requested  [2021/07]
10.11.2020Date on which the examining division has become responsible
14.04.2021Observations by third parties
04.01.2022Communication of intention to grant the patent
05.01.2022Fee for grant paid
05.01.2022Fee for publishing/printing paid
05.01.2022Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP13727570.7  / EP2854762
EP19161189.6  / EP3536310
Opposition(s)Opponent(s)01  04.11.2022  06.02.2025  WITHDRAWN
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  14.11.2022  05.03.2024  WITHDRAWN
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
Opponent's representative
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
 03  15.11.2022  21.11.2022  ADMISSIBLE
Strawman Limited
Office 9 Dalton House
60 Windsor Avenue
London SW19 2RR / GB
Opponent's representative
Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
 04  15.11.2022  21.11.2022  ADMISSIBLE
Ehlers, Jochen
Eisenführ Speiser
Johannes-Brahms-Platz 1
20355 Hamburg / DE
Opponent's representative
Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Johannes-Brahms-Platz 1
20355 Hamburg / DE
 05  16.11.2022  19.12.2023  WITHDRAWN
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
 06  16.11.2022  14.04.2025  WITHDRAWN
Wess, Wolfgang
Rotkäppchenstr. 88a
81739 München / DE
Opponent's representative
SSM Sandmair
Patentanwälte Rechtsanwalt
Partnerschaft mbB
Joseph-Wild-Straße 20
81829 München / DE
 [2026/16]
Former [2025/21]
Opponent(s)01  04.11.2022  06.02.2025  WITHDRAWN
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  14.11.2022  05.03.2024  WITHDRAWN
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
Opponent's representative
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
 03  15.11.2022  21.11.2022  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
 04  15.11.2022  21.11.2022  ADMISSIBLE
Ehlers, Jochen
Eisenführ Speiser
Johannes-Brahms-Platz 1
20355 Hamburg / DE
Opponent's representative
Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Johannes-Brahms-Platz 1
20355 Hamburg / DE
 05  16.11.2022  19.12.2023  WITHDRAWN
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
 06  16.11.2022  14.04.2025  WITHDRAWN
Wess, Wolfgang
Rotkäppchenstr. 88a
81739 München / DE
Opponent's representative
SSM Sandmair
Patentanwälte Rechtsanwalt
Partnerschaft mbB
Joseph-Wild-Straße 20
81829 München / DE
Former [2025/16]
Opponent(s)01  04.11.2022  06.02.2025  WITHDRAWN
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  14.11.2022  05.03.2024  WITHDRAWN
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
Opponent's representative
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
 03  15.11.2022  21.11.2022  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
 04  15.11.2022  21.11.2022  ADMISSIBLE
Ehlers, Jochen
Eisenführ Speiser
Johannes-Brahms-Platz 1
20355 Hamburg / DE
Opponent's representative
Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Johannes-Brahms-Platz 1
20355 Hamburg / DE
 05  16.11.2022  19.12.2023  WITHDRAWN
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
 06  16.11.2022  21.11.2022  ADMISSIBLE
Wess, Wolfgang
Rotkäppchenstr. 88a
81739 München / DE
Opponent's representative
SSM Sandmair
Patentanwälte Rechtsanwalt
Partnerschaft mbB
Joseph-Wild-Straße 20
81829 München / DE
Former [2025/12]
Opponent(s)01  04.11.2022  06.02.2025  WITHDRAWN
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  14.11.2022  05.03.2024  WITHDRAWN
Keil & Schaafhausen Patentanwälte PartGmbB
Friedrichstraße 2-6
60323 Frankfurt am Main / DE
Opponent's representative
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
 03  15.11.2022  21.11.2022  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
 04  15.11.2022  21.11.2022  ADMISSIBLE
Ehlers, Jochen
Eisenführ Speiser
Johannes-Brahms-Platz 1
20355 Hamburg / DE
Opponent's representative
Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Johannes-Brahms-Platz 1
20355 Hamburg / DE
 05  16.11.2022  19.12.2023  WITHDRAWN
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
 06  16.11.2022  21.11.2022  ADMISSIBLE
Wess, Wolfgang
Rotkäppchenstr. 88a
81739 München / DE
Opponent's representative
SSM Sandmair
Patentanwälte Rechtsanwalt
Partnerschaft mbB
Joseph-Wild-Straße 20
81829 München / DE
Former [2024/15]
Opponent(s)01  04.11.2022  07.11.2022  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  14.11.2022  05.03.2024  WITHDRAWN
Keil & Schaafhausen Patentanwälte PartGmbB
Friedrichstraße 2-6
60323 Frankfurt am Main / DE
Opponent's representative
Keil & Schaafhausen Patentanwälte PartGmbB
Bockenheimer Landstraße 25
60325 Frankfurt am Main / DE
 03  15.11.2022  21.11.2022  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
 04  15.11.2022  21.11.2022  ADMISSIBLE
Ehlers, Jochen
Eisenführ Speiser
Johannes-Brahms-Platz 1
20355 Hamburg / DE
Opponent's representative
Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Johannes-Brahms-Platz 1
20355 Hamburg / DE
 05  16.11.2022  19.12.2023  WITHDRAWN
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
 06  16.11.2022  21.11.2022  ADMISSIBLE
Wess, Wolfgang
Rotkäppchenstr. 88a
81739 München / DE
Opponent's representative
SSM Sandmair
Patentanwälte Rechtsanwalt
Partnerschaft mbB
Joseph-Wild-Straße 20
81829 München / DE
Former [2024/04]
Opponent(s)01  04.11.2022  07.11.2022  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  14.11.2022  21.11.2022  ADMISSIBLE
Keil & Schaafhausen Patentanwälte PartGmbB
Friedrichstraße 2-6
60323 Frankfurt am Main / DE
Opponent's representative
Keil & Schaafhausen Patentanwälte PartGmbB
Friedrichstraße 2-6
60323 Frankfurt am Main / DE
 03  15.11.2022  21.11.2022  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
 04  15.11.2022  21.11.2022  ADMISSIBLE
Ehlers, Jochen
Eisenführ Speiser
Johannes-Brahms-Platz 1
20355 Hamburg / DE
Opponent's representative
Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Johannes-Brahms-Platz 1
20355 Hamburg / DE
 05  16.11.2022  19.12.2023  WITHDRAWN
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
 06  16.11.2022  21.11.2022  ADMISSIBLE
Wess, Wolfgang
Rotkäppchenstr. 88a
81739 München / DE
Opponent's representative
SSM Sandmair
Patentanwälte Rechtsanwalt
Partnerschaft mbB
Joseph-Wild-Straße 20
81829 München / DE
Former [2022/52]
Opponent(s)01  04.11.2022  07.11.2022  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
 02  14.11.2022  21.11.2022  ADMISSIBLE
Keil & Schaafhausen Patentanwälte PartGmbB
Friedrichstraße 2-6
60323 Frankfurt am Main / DE
Opponent's representative
Keil & Schaafhausen Patentanwälte PartGmbB
Friedrichstraße 2-6
60323 Frankfurt am Main / DE
 03  15.11.2022  21.11.2022  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
 04  15.11.2022  21.11.2022  ADMISSIBLE
Ehlers, Jochen
Eisenführ Speiser
Johannes-Brahms-Platz 1
20355 Hamburg / DE
Opponent's representative
Eisenführ Speiser
Patentanwälte Rechtsanwälte PartGmbB
Johannes-Brahms-Platz 1
20355 Hamburg / DE
 05  16.11.2022  21.11.2022  ADMISSIBLE
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
Opponent's representative
Hamm&Wittkopp Patentanwälte PartmbB
Jungfernstieg 38
20354 Hamburg / DE
 06  16.11.2022  21.11.2022  ADMISSIBLE
Wess, Wolfgang
Rotkäppchenstr. 88a
81739 München / DE
Opponent's representative
SSM Sandmair
Patentanwälte Rechtsanwalt
Partnerschaft mbB
Joseph-Wild-Straße 20
81829 München / DE
Former [2022/50]
Opponent(s)01  04.11.2022  07.11.2022  ADMISSIBLE
Teva Pharmaceutical Industries Ltd.
124 Dvora HaNevi'a St.
6944020 Tel Aviv / IL
Opponent's representative
Elkington and Fife LLP
Prospect House
8 Pembroke Road
Sevenoaks, Kent TN13 1XR / GB
01.12.2022Invitation to proprietor to file observations on the notice of opposition
09.06.2023Reply of patent proprietor to notice(s) of opposition
10.09.2024Cancellation of oral proceeding that was planned for 05.02.2025
05.02.2025Date of oral proceedings
08.10.2025Date of oral proceedings
10.12.2025Despatch of minutes of oral proceedings
10.12.2025Despatch of communication that the patent will be revoked
Appeal following opposition09.02.2026Appeal received No.  T0269/26
09.02.2026Payment of appeal fee
Fees paidRenewal fee
29.09.2020Renewal fee patent year 03
29.09.2020Renewal fee patent year 04
29.09.2020Renewal fee patent year 05
29.09.2020Renewal fee patent year 06
29.09.2020Renewal fee patent year 07
29.09.2020Renewal fee patent year 08
13.05.2021Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL16.02.2022
MC16.02.2022
MK16.02.2022
RS16.02.2022
SM16.02.2022
BG30.05.2023
CY30.05.2023
FI30.05.2023
HR30.05.2023
LT30.05.2023
LV30.05.2023
RO30.05.2023
EE31.05.2023
HU31.05.2023
NO31.05.2023
GB10.08.2023
IS04.12.2023
[2025/47]
Former [2024/51]AL16.02.2022
MC16.02.2022
MK16.02.2022
RS16.02.2022
SM16.02.2022
BG30.05.2023
CY30.05.2023
FI30.05.2023
HR30.05.2023
LT30.05.2023
LV30.05.2023
RO30.05.2023
EE31.05.2023
HU31.05.2023
NO31.05.2023
GB10.08.2023
Former [2024/23]AL16.02.2022
MC16.02.2022
MK16.02.2022
RS16.02.2022
SM16.02.2022
CY30.05.2023
FI30.05.2023
HR30.05.2023
LT30.05.2023
LV30.05.2023
RO30.05.2023
EE31.05.2023
HU31.05.2023
NO31.05.2023
GB10.08.2023
Former [2024/11]AL16.02.2022
MC16.02.2022
RS16.02.2022
SM16.02.2022
CY30.05.2023
FI30.05.2023
HR30.05.2023
LT30.05.2023
LV30.05.2023
RO30.05.2023
EE31.05.2023
HU31.05.2023
NO31.05.2023
GB10.08.2023
Former [2024/09]AL16.02.2022
MC16.02.2022
RS16.02.2022
SM16.02.2022
CY30.05.2023
FI30.05.2023
LT30.05.2023
HU31.05.2023
NO31.05.2023
GB10.08.2023
Former [2024/08]AL16.02.2022
MC16.02.2022
RS16.02.2022
SM16.02.2022
CY30.05.2023
LT30.05.2023
NO31.05.2023
GB10.08.2023
Former [2023/47]AL16.02.2022
MC16.02.2022
RS16.02.2022
SM16.02.2022
GB10.08.2023
Former [2023/06]AL16.02.2022
MC16.02.2022
RS16.02.2022
SM16.02.2022
Former [2023/01]AL16.02.2022
RS16.02.2022
SM16.02.2022
Former [2022/47]RS16.02.2022
SM16.02.2022
Former [2022/35]RS16.02.2022
Documents cited:Search[Y] WO2011006877  (NOVARTIS AG et al.)
 [Y] WO2007035621  (OSI EYETECH INC et al.)
 [Y] US2006293270  (ADAMIS ANTHONY P et al.)
 [Y] US8075535  (CARREL FRANCK et al.)
 [Y] US4946441  (LADEROUTE MAURICE et al.) * D4a English translation of D4 *
 [A] EP1488818  (NIPPON BECTON DICKINSON COMPAN et al.)
 [A] EP2298392  (DENKI KAGAKU KOGYO KK et al.)
 [A] DE102008005938  (VETTER & CO APOTHEKER et al.)
by applicantWO2005121176
otherWO2004091700
OppositionEP3536310
 WO2019005072
 JP2004313369
 WO2011006877
 US7060269
 US8075535
 EP2682145
 US5597530
 US8075535
 US5607400
 US2009247957
 WO9955402
 US5607399
 US5667495
 WO2006047325
 EP2047877
 JP2004313369
 US7678078
 JP2002177388
 US5405326
 EP0738517
 US5688252
 JP2012045046
 JP2001340455
 WO2011006877
 WO2007035621
 EP2047877
 JP2002177388
 EP0738517
 US7678078
 US4946441
 JP2004313369
 EP2682145
 WO2007035621
 US2007250017
 EP2298392
 WO2011006877
 US4252118
 US2010181218
 US8075535
 EP2047877
 US4946441
 US2602447
 US2003034264
 US2009131869
 WO9413339
 US2005129569
 JP2009284951
 US2011137263
 US2012078224
 US5173258
 EP2854762
 WO2004091700
 EP2436413
 JP2000014779
 WO2011006877
 EP2047877
 US4946441
 EP2298392
 EP0764450
 US5607399
 US8137324
 US2012109072
 US2005192544
 US2003032928
 WO2008077155
 US4252118
 US6090081
 WO2009030976
 US2012078224
 US2005148947
 EP0971749
 WO9744068
 JPH0725953
 WO2014005728
   ISO: "Sterilization of health care products Vocabulary of terms used in sterilization and related equipment and process standards. Extract", INTERNATIONAL STANDARD ISO 11139 -FIRST EDITION 2018-08, 1 August 2018 (2018-08-01), pages 28 - 29, XP055981258
   ANONYMOUS: "Lucentis'' Material Safety Data Sheet", GENENTECH, INC., 22 May 2009 (2009-05-22), pages 1 - 5, XP093002580
   ANONYMOUS: "Lucentis - highlights of prescribing information", LUCENTIS, June 2010 (2010-06-01), pages 1 - 7, XP093002595
   ANONYMOUS: "Highlights of prescribing information these highlights do not include all of the information needed to use macugen safely and effectively.", MACUGEN, July 2011 (2011-07-01), pages 1 - 10, XP093002555
   ANONYMOUS: "Glass barrels for injectables", ISO 110410 PREFILLED SYRINGES, 1 February 2007 (2007-02-01), pages 1 - 16, XP093002899
   ANDREA WAGNER: "Advances in Prefilled Syringe Technology", ITP, vol. 24, 2007, pages 73 - 75, XP055427527
   ANONYMOUS: "Division of Transplant and Ophthalmology Products Advisory Committee Meeting Briefing Package for Aflibercept injection for the treatment of patients with neovascular (wet0 age-related macular degeneration (AMD)", DTOP-AFLIBERCEPT BRIEFING PACKAGE FOR ADVISORY MEETING, 2011, pages 1 - 70, XP093002913
   ISO/ TS 11139:2006, January 2006 (2006-01-01)
   "Ophthalmic Surgery: Principles and Prac- tice, E-Book", 1 January 2011, article SPAETH GEORGE L.: "lntravitreal injection of drug", pages: 511 - 512, XP093003875
   GERDING H., TIMMERMANN M, : "Accuracy and Precision of Intravitreally Injected Ranibi- zumab Doses: An Experimental Study Experimentelle Untersuchungen zur Genauigkeit und Przision der Dosierung intravitrealer Injektionen von Ranibizumab", ACCURACY AND PRECISION KLIN MONATSBL AUGENHEILKD, vol. 227, 20 April 2010 (2010-04-20), pages 269 - 272, XP093003872
   AZAD RAJVARDHAN, RUNDA NEELAM, KUMAR ATUL, SHARMA YOGRAJ, CHANDRA PARIJAT: "To Compare Photodynamic Therapy with Ranibizumab vs Photodynamic Therapy with Pegaptanib for Subfoveal Choroidal Neovascularization in Age-related Macular Degeneration", WORLD JOURNAL OF RETINA & VITREOUS, vol. 2, 15 May 2012 (2012-05-15), pages 23 - 27, XP093003870, ISSN: 2249-0477, DOI: 10.5005/jp-journals-10020-1024

DOI:   http://dx.doi.org/10.5005/jp-journals-10020-1024
   ANONYMOUS: "Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration", N ENGL J MED, vol. 364, no. 20, 19 May 2011 (2011-05-19), pages 1897 - 1908, XP055972148
   KIM, J.E. ; MANTRAVADI, A.V. ; HUR, E.Y. ; COVERT, D.J.: "Short-term Intraocular Pressure Changes Immediately After Intravitreal Injections of Anti-Vascular Endothelial Growth Factor Agents", AMERICAN JOURNAL OF OPHTHALMOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 146, no. 6, 1 December 2008 (2008-12-01), AMSTERDAM, NL , pages 930 - 934.e1, XP025681704, ISSN: 0002-9394, DOI: 10.1016/j.ajo.2008.07.007

DOI:   http://dx.doi.org/10.1016/j.ajo.2008.07.007
   "Hugo and Russe ll's pharmaceutical microbiology", 1 January 2008, article DENYER STEPHEN P., NORMAN A. HODGES, SEAN P. GORMAN: "Sterilization procedures and sterility assurance", pages: 327, 350, XP093003865
   COONEY PETER, MAMANE WILLIAM G.: "Guidance for Industry for the Submission Documentation for Sterilization Process Validation Applications for Human and Veterinary Drug Products", CDR - CVM, 1 November 1994 (1994-11-01), XP093003857, [retrieved on 20221201]
   "US Pharmacopeia National Formulary. Vol 11", vol. 11, 1 May 2011, article ANONYMOUS: "Ophthalmic solutions", pages: 328 - 329, XP093003855
   ANONYMOUS: "Stainless steel needle tubing for manufacture of medical devices (ISO 9626:1991 + AMD 1:2001) (including amendment A1:2001); German version EN ISO 9626:1995 + A1:2001", DIN EN ISO 9626 : 2002-03, 1 March 2002 (2002-03-01), XP093003852, [retrieved on 20221201]
   LINCOFF HARVEY, COLEMAN JACKSON, KREISSIG INGRID, RICHARD GISBERT, CHANG STANLEY, WILCOX LLOYD M.: "The Perfluorocarbon Gases in the Treatment of Retinal Detachment", OPHTHALMOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 90, no. 5, 1 May 1983 (1983-05-01), AMSTERDAM, NL, pages 546 - 551, XP093003853, ISSN: 0161-6420, DOI: 10.1016/S0161-6420(83)34525-5

DOI:   http://dx.doi.org/10.1016/S0161-6420(83)34525-5
   "HIGHLIGHTS OF PRESCRIBING INFORMATION", NDA 21-756/S-018, July 2011 (2011-07-01), pages 3 - 12, XP093002555, Retrieved from the Internet
   ANONYMOUS: "ISO 11040-4", INTERNATIONAL STANDARD, 1 February 2007 (2007-02-01), XP093003391, [retrieved on 20221130]
   ANONYMOUS: "ISO 11040-6", INTERNATIONAL STANDARD, 1 April 2012 (2012-04-01), XP093003395, [retrieved on 20221130]
   ANONYMOUS: "SYRINGES FOR CHROMATOGRAPHIC AND ANALYTICAL APPLICATIONS ", SIGMA ALDRICH BROCHURE, 1 January 2007 (2007-01-01), XP093003401
   ANONYMOUS: "Division of Transplant and Ophthalmology Products Advisory Committee Meeting Briefing Package for Aflibercept injection for the treatment of patients with neovascular (wet0 age-related macular degeneration (AMD)", DTOP-AFLIBERCEPT BRIEFING PACKAGE FOR ADVISORY MEETING, 1 January 2011 (2011-01-01), pages 1 - 70, XP093002913, [retrieved on 20221129]
   WEBSITE ENTRY OF THE US FOOD AND DRUG ADMINISTRATION (FDA, Retrieved from the Internet
   WEBSITE ENTRY OF THE US FOOD AND DRUG ADMINISTRATION (FDA, Retrieved from the Internet
   ANONYMOUS: "Product information EYLEA aflibercept (rich)", 7 March 2012 (2012-03-07), pages 1 - 18, XP055899118, [retrieved on 20220309]
   ANONYMOUS: "PRODUCT INFORMATION FOR PUBLICATION ", THERAPEUTIC GOODS, 6 June 2012 (2012-06-06), XP093003793, [retrieved on 20221201]
   BRUNO REUTER, PETERSEN CLAUDIA, GERRESHEIMER BüNDE, GMBH, BüNDE: "Syringe Siliconization Trends, methods, analysis procedures", 1 January 2012 (2012-01-01), XP055658634, Retrieved from the Internet [retrieved on 20200116]
   SLOCIK JOSEPH M., DENNIS PATRICK B., KUANG ZHIFENG, PELTON ANTHONY, NAIK RAJESH R.: "Creation of stable water-free antibody based protein liquids", COMMUNICATIONS MATERIALS, vol. 2, no. 1, 1 December 2021 (2021-12-01), XP055900234, DOI: 10.1038/s43246-021-00222-2

DOI:   http://dx.doi.org/10.1038/s43246-021-00222-2
   ANONYMOUS: "Components for prefilled syringes ", DATWYLER, 1 October 2011 (2011-10-01), XP093142376, [retrieved on 20240318]
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.