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EP3917935
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EP About this file: EP3917935
| EP3917935 - SYNTHETIC PROCESS AND NOVEL INTERMEDIATES [Right-click to bookmark this link] | Status | The application has been withdrawn Status updated on 22.12.2023 Database last updated on 17.05.2024 | |
| Former | Request for examination was made Status updated on 05.11.2021 | ||
| Former | The international publication has been made Status updated on 08.08.2020 | Most recent event Tooltip | 22.12.2023 | Withdrawal of application | published on 24.01.2024 [2024/04] | Applicant(s) | For all designated states Avista Pharma Solutions, Inc. 3501 Tricenter Blvd. Suite C Durham, NC 27713 / US | [2021/49] | Inventor(s) | 01 /
SPEAKE, Jason, D. 1714 Woodstone Drive Winston-Salem, NC 27127 / US | 02 /
PERALES, Joe, B. 507 North Waters Edge Drive Durham, NC 27703 / US | 03 /
BECK, Brent, Christopher 1910 Park Stream Court Apex, NC 27502 / US | 04 /
PANDI, Bharathi 112 Deer Isle Court Cary, NC 27519 / US | [N/P] |
| Former [2021/49] | 01 /
SPEAKE, Jason, D. Winston-Salem, NC 27127 / US | ||
| 02 /
PERALES, Joe, B. Durham, NC 27703 / US | |||
| 03 /
BECK, Brent, Christopher Apex, NC 27502 / US | |||
| 04 /
PANDI, Bharathi Cary, NC 27519 / US | Representative(s) | Potter Clarkson Chapel Quarter Mount Street Nottingham NG1 6HQ / GB | [N/P] |
| Former [2021/49] | Potter Clarkson The Belgrave Centre Talbot Street Nottingham NG1 5GG / GB | Application number, filing date | 20748460.1 | 29.01.2020 | [2021/49] | WO2020US15556 | Priority number, date | US201962798735P | 30.01.2019 Original published format: US 201962798735 P | [2021/49] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2020160074 | Date: | 06.08.2020 | Language: | EN | [2020/32] | Type: | A1 Application with search report | No.: | EP3917935 | Date: | 08.12.2021 | Language: | EN | The application published by WIPO in one of the EPO official languages on 06.08.2020 takes the place of the publication of the European patent application. | [2021/49] | Search report(s) | International search report - published on: | KR | 06.08.2020 | (Supplementary) European search report - dispatched on: | EP | 14.10.2022 | Classification | IPC: | C07F5/02, C07D487/04, A61K31/69, A61K31/4985, A61P19/02, A61P29/00 | [2021/49] | CPC: |
C07D487/04 (EP,US);
C07F5/025 (EP)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2021/49] | Title | German: | SYNTHETISCHER PROZESS UND NEUARTIGE ZWISCHENPRODUKTE | [2021/49] | English: | SYNTHETIC PROCESS AND NOVEL INTERMEDIATES | [2021/49] | French: | PROCÉDÉ DE SYNTHÈSE ET NOUVEAUX INTERMÉDIAIRES | [2021/49] | Entry into regional phase | 02.08.2021 | National basic fee paid | 02.08.2021 | Search fee paid | 02.08.2021 | Designation fee(s) paid | 02.08.2021 | Examination fee paid | Examination procedure | 02.08.2021 | Examination requested [2021/49] | 17.03.2023 | Amendment by applicant (claims and/or description) | 18.12.2023 | Application withdrawn by applicant [2024/04] | Fees paid | Renewal fee | 27.01.2022 | Renewal fee patent year 03 | 27.01.2023 | Renewal fee patent year 04 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]WO2006019768 (SCHERING CORP [US], et al) [A] 1-8* the method disclosed on page 113, method B: reacting 3-iodo-7-pyridin-4-yl-imidazo[l,2-a]pyridine and 2-[4-(4,4,5, 5-tetramethyl-[l,3,2]dioxaborolan-2-yl)-phenyl]-N-(3-trifluoromethyl-phenyl)-acetamide to give the C-C-coupled product *; | [A]WO2006091671 (LILLY CO ELI [US], et al) [A] 1-8 * C-C coupling reaction between 1004B and 1004C on page 114 *; | [T]WO2019245590 (AVISTA PHARMA SOLUTIONS INC [US]) [T] 1 * method for C-C coupling with a 3-halo-imidazo-pyrazine on page 23: *; | [T]WO2020160075 (AVISTA PHARMA SOLUTIONS INC [US]) [T] 1-8 | International search | [A]WO03087061 (PFIZER PHARMA [JP], et al) [A] 1-8; | [A]WO2011041713 (GLAXOSMITHKLINE LLC [US], et al) [A] 1-8; | [A]CN104649945 (UNIV CHINA AGRICULTURAL) [A] 1-8; | [A] - Kazunari Nakao, Et Al, "CJ-023,423, a Novel, Potent and Selective Prostaglandin EP4 Receptor Antagonist with Antihyperalgesic Properties", THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, (20070101), vol. 322, no. 2, doi:10.1124/jpet.107.122010, pages 686 - 694, XP055358062 [A] 1-8 DOI: http://dx.doi.org/10.1124/jpet.107.122010 | [A] - Vito Virgina De; Saba Alessandro; Lee Hong-Ki; Owen Helen; Poapolathep Amnart; Giorgi Mario, "Detection and quantification of the selective EP4 receptor antagonist CJ-023423 (grapiprant) in canine plasma by HPLC with spectrofluorimetric detection", Journal of Pharmaceutical and Biomedical Analysis, Elsevier B.V., AMSTERDAM, NL, AMSTERDAM, NL, (20151107), vol. 118, doi:10.1016/j.jpba.2015.11.004, ISSN 0731-7085, pages 251 - 258, XP029343680 [A] 1-8 DOI: http://dx.doi.org/10.1016/j.jpba.2015.11.004 | by applicant | WO0232422 | WO0232900 | WO03087061 | WO03086371 | US2004220189 | US2005009832 | WO2006019768 | WO2006091671 | WO2006095268 | WO2011041713 | WO2011102149 | WO2011113862 | WO2011151259 | US2013195848 | WO2014078813 | WO2014148053 | CN104649945 | WO2018013430 | WO2019245590 | WO2020160075 | - KAZUNARI NAKAO et al., "CJ-023,423 a Novel, Potent and Selective Prostaglandin EP4 Receptor Antagoninst with Antihyperalgesic Properties", The Journal of Pharmacology and Experimental Therapeutics, (20070101), vol. 322, no. 2, doi:10.1124/jpet.107.122010, pages 686 - 694, XP055358062 DOI: http://dx.doi.org/10.1124/jpet.107.122010 | - DE VITO et al., "Detection and quantification of the selective EP4 receptor antagonist CJ-023423 (grapiprant) in canine plasma by HPLC with spectrofluorimetric detection", Journal of Pharmaceutical and Biomedical Analysis, (20151107), vol. 118, doi:10.1016/j.jpba.2015.11.004, pages 251 - 258, XP029343680 DOI: http://dx.doi.org/10.1016/j.jpba.2015.11.004 | - Prog. Med., (19850000), vol. 5, pages 2157 - 2161 | - Pharmaceutical Research and Development, Hirokawa Publishing Company, (19900000), vol. 7 | - Drug Design, pages 163 - 198 | - CAHN et al., Angew. Chem., (19660000), vol. 78, pages 413 - 447 | - Angew. Chem., Int. Ed. Engl., vol. 5, pages 511 - 414 | - PRELOGHELMCHEN, Angew. Chem., (19820000), vol. 94, pages 614 - 631 | - Angew. Chem. Internat. Ed. Eng., vol. 21, pages 567 - 583 | - MATALOBO, Tetrahedron: Asymmetry, (19930000), vol. 4, pages 657 - 668 | US19380627987 | WO2018US46142 |