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Extract from the Register of European Patents

EP About this file: EP4013860

EP4013860 - CASPASE-2 VARIANTS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  19.01.2024
Database last updated on 19.10.2024
FormerRequest for examination was made
Status updated on  20.05.2022
FormerThe international publication has been made
Status updated on  19.02.2021
Formerunknown
Status updated on  22.08.2020
Most recent event   Tooltip03.09.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Boehringer Ingelheim RCV GmbH & Co KG
Dr. Boehringer-Gasse 5-11
1121 Wien / AT
[2022/25]
Inventor(s)01 / JUNGBAUER, Alois
Universität für Bodenkultur Wien Gregor-Mendel-
Strasse 33
1180 Vienna / AT
02 / LINGG, Nico
Universität für Bodenkultur Wien Gregor-Mendel-
Strasse 33
1180 Wien / AT
03 / STRIEDNER, Gerald
Universität für Bodenkultur Wien Gregor-Mendel-
Strasse 33
1180 Wien / AT
04 / CSERJAN-PUSCHMANN, Monika
Universität für Bodenkultur Wien Gregor-Mendel-
Strasse 33
1180 Wien / AT
05 / OOSTENBRINK, Chris
Universität für Bodenkultur Wien Gregor-Mendel-
Strasse 33
1180 Wien / AT
06 / ÖHLKNECHT, Christoph
ACIB GmbH Krenngasse 37
8010 Graz / AT
07 / KRÖSS, Christina
ACIB GmbH Krenngasse 37
8010 Graz / AT
08 / ENGELE, Petra
ACIB GmbH Krenngasse 37
8010 Graz / AT
09 / SCHNEIDER, Rainer
Bruder Willramstrasse 27a
6300 Wörgl / AT
 [2022/25]
Representative(s)Weinzinger, Philipp, et al
Sonn Patentanwälte GmbH & Co KG
Riemergasse 14
1010 Wien / AT
[N/P]
Former [2022/25]Simon, Elke Anna Maria, et al
Boehringer Ingelheim International GmbH
Corporate Patents
Binger Strasse 173
55216 Ingelheim am Rhein / DE
Application number, filing date20754767.014.08.2020
[2022/25]
WO2020EP72934
Priority number, dateEP2019019176714.08.2019         Original published format: EP 19191767
[2022/25]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021028590
Date:18.02.2021
Language:EN
[2021/07]
Type: A1 Application with search report 
No.:EP4013860
Date:22.06.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 18.02.2021 takes the place of the publication of the European patent application.
[2022/25]
Search report(s)International search report - published on:EP18.02.2021
ClassificationIPC:C12N9/64, C12P21/00
[2022/25]
CPC:
C12P21/06 (EP,CN,KR); C12N9/6472 (EP,CN,KR); C12N9/14 (US);
A61P25/16 (CN); A61P25/28 (CN); A61P29/00 (CN);
A61P35/00 (CN); C12N15/70 (CN,US); C12P21/02 (EP,KR);
C12Y304/22055 (EP,CN,KR,US); A61K38/00 (CN); C07K2319/00 (EP,CN);
C07K2319/02 (CN); C07K2319/20 (EP,CN,KR); C07K2319/21 (CN);
C07K2319/40 (EP,CN,KR); C07K2319/50 (EP,CN,KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/25]
Extension statesBA14.03.2022
ME14.03.2022
Validation statesKH14.03.2022
MA14.03.2022
MD14.03.2022
TN14.03.2022
TitleGerman:CASPASE-2-VARIANTEN[2022/25]
English:CASPASE-2 VARIANTS[2022/25]
French:VARIANTS DE CASPASE 2[2022/25]
Entry into regional phase14.03.2022National basic fee paid 
14.03.2022Designation fee(s) paid 
14.03.2022Examination fee paid 
Examination procedure14.03.2022Examination requested  [2022/25]
14.03.2022Date on which the examining division has become responsible
22.09.2022Amendment by applicant (claims and/or description)
22.01.2024Despatch of a communication from the examining division (Time limit: M06)
19.07.2024Reply to a communication from the examining division
Fees paidRenewal fee
31.08.2022Renewal fee patent year 03
31.08.2023Renewal fee patent year 04
02.09.2024Renewal fee patent year 05
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Cited inInternational search[A]WO2005049847  (NOVO NORDISK AS [DK], et al) [A] 1-74,92-95 * example 1; claim 10 *;
 [XY]WO2009044988  (KOREA RES INST OF BIOSCIENCE [KR], et al) [X] 74 * claims 1,9; sequence 73 * [Y] 1-73,92-95;
 [XI]  - SRINIVASA M SRINIVASULA ET AL, "Generation of constitutively active recombinant Caspases-3 and -6 by rearrangement of their subunits", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, (19980424), vol. 273, no. 17, doi:10.1074/JBC.273.17.10107, ISSN 0021-9258, pages 10107 - 10111, XP002111125 [X] 1-6,8-10,17-20,22-24,30-32,34,35,45,46,58-66 * figure 1 * [I] 7,11-16,21,25-29,33,36-44,47-57,67-74,92-95

DOI:   http://dx.doi.org/10.1074/jbc.273.17.10107
 [IY]  - S Lok, "CASP2 from Castor canadensis (American beaver)", (20171122), URL: https://www.uniprot.org/uniprot/A0A250YIA5.txt, (20200121), XP055659849 [I] 74 * the whole document * [Y] 1-73,92-95
 [AD]  - GARCIA-CALVO M ET AL, "PURIFICATION AND CATALYTIC PROPERTIES OF HUMAN CASPASE FAMILY MEMBERS", CELL DEATH AND DIFFERENTIATION, NATURE PUBLISHING GROUP, GB, (19990101), vol. 6, doi:10.1038/SJ.CDD.4400497, ISSN 1350-9047, pages 362 - 369, XP002907203 [AD] 1-74,92-95 * figure 1; table 1 *

DOI:   http://dx.doi.org/10.1038/sj.cdd.4400497
 [A]  - Sarah H. Mackenzie ET AL, "Death by Caspase Dimerization", Retinal Degenerative Diseases: Advances inExperimental Medicine and Biology, US, Springer, (20120101), vol. 747, pages 55 - 73, doi:10.1007/978-1-4614-3229-6_4, ISSN 0065-2598, XP055570209 [A] 1-74,92-95 * figure 1; table 1 *

DOI:   http://dx.doi.org/10.1007/978-1-4614-3229-6_4
 [XA]  - YU Y ET AL, "Circular permutation: a different way to engineer enzyme structure and function", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 29, no. 1, ISSN 0167-7799, (20110101), pages 18 - 25, (20101222), XP027571103 [X] 47-49,67-69 * abstract * [A] 1-46,50-66,70-74,92-95
by applicantUS6379950
 EP1597369
 WO2009044988
 US7604980
 US8535908
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DOI:   http://dx.doi.org/10.1007/s00253-012-4507-0
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DOI:   http://dx.doi.org/10.1074/jbc.272.29.17907
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