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EP3927811
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| EP3927811 - BIOFUNCTIONALIZED HYDROGEL FOR CELL CULTURE [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 26.11.2021 Database last updated on 03.06.2024 | |
| Former | The international publication has been made Status updated on 28.08.2020 | Most recent event Tooltip | 27.02.2024 | New entry: Renewal fee paid | Applicant(s) | For all designated states Vanderbilt University 305 Kirkland Hall 2201 West End Avenue Nashville, TN 37240 / US | [2021/52] | Inventor(s) | 01 /
LIPPMANN, Ethan, S. C/o Vanderbilt University 305 Kirland Hall 2201 West End Avenue Nashville, TN 37240 / US | 02 /
BALOTIN, Kylie C/o Vanderbilt University 305 Kirkland Hall 2201 West End Avenue Nashville, TN 37240 / US | 03 /
O'GRADY, Brian C/o Vanderbilt University 305 Kirkland Hall 2201 West End Avenue Nashville, TN 37240 / US | 04 /
BELLAN, Leon, M. C/o Vanderbilt University 305 Kirkland Hall 2201 West End Avenue Nashville, TN 37240 / US | [N/P] |
| Former [2021/52] | 01 /
LIPPMANN, Ethan, S. Nashville, TN 37240 / US | ||
| 02 /
BALOTIN, Kylie Nashville, TN 37240 / US | |||
| 03 /
O'GRADY, Brian Nashville, TN 37240 / US | |||
| 04 /
BELLAN, Leon, M. Nashville, TN 37240 / US | Representative(s) | Marks & Clerk LLP 15 Fetter Lane London EC4A 1BW / GB | [N/P] |
| Former [2021/52] | Stafford, Jonathan Alan Lewis Marks & Clerk LLP 1 New York Street Manchester M1 4HD / GB | Application number, filing date | 20759186.8 | 21.02.2020 | [2021/52] | WO2020US19369 | Priority number, date | US201962809184P | 22.02.2019 Original published format: US 201962809184 P | US201962828806P | 03.04.2019 Original published format: US 201962828806 P | US201962857575P | 05.06.2019 Original published format: US 201962857575 P | [2021/52] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2020172637 | Date: | 27.08.2020 | Language: | EN | [2020/35] | Type: | A1 Application with search report | No.: | EP3927811 | Date: | 29.12.2021 | Language: | EN | The application published by WIPO in one of the EPO official languages on 27.08.2020 takes the place of the publication of the European patent application. | [2021/52] | Search report(s) | International search report - published on: | US | 27.08.2020 | (Supplementary) European search report - dispatched on: | EP | 20.10.2022 | Classification | IPC: | C12N5/00, C07K7/04, C07K14/00, C07K17/08, C07K14/78 | [2022/47] | CPC: |
C07K17/08 (EP);
C12N5/0697 (US);
C07K14/78 (EP);
C08H1/06 (US);
C08J3/075 (US);
C08J3/24 (US);
C08L89/06 (US);
C12N5/0068 (EP);
C12N5/0619 (US);
C12N5/0622 (US);
C12N5/0691 (US);
C08J2389/06 (US);
C08L2312/00 (US);
C12N2500/32 (EP);
C12N2502/081 (US);
C12N2502/086 (US);
C12N2506/45 (US);
C12N2513/00 (US);
|
| Former IPC [2021/52] | C12N5/00, C07K7/04, C07K14/00 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2021/52] | Title | German: | BIOFUNKTIONALISIERTES HYDROGEL FÜR ZELLKULTUR | [2021/52] | English: | BIOFUNCTIONALIZED HYDROGEL FOR CELL CULTURE | [2021/52] | French: | HYDROGEL BIOFONCTIONNALISÉ POUR CULTURE CELLULAIRE | [2021/52] | Entry into regional phase | 12.08.2021 | National basic fee paid | 12.08.2021 | Search fee paid | 12.08.2021 | Designation fee(s) paid | 12.08.2021 | Examination fee paid | Examination procedure | 12.08.2021 | Examination requested [2021/52] | 18.05.2023 | Amendment by applicant (claims and/or description) | Fees paid | Renewal fee | 25.02.2022 | Renewal fee patent year 03 | 27.02.2023 | Renewal fee patent year 04 | 27.02.2024 | Renewal fee patent year 05 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]US2018171286 (BANERJEE IPSITA [US], et al) [X] 1-7,10-12,14,15 * General cross-linking in hydrogels; paragraphs [0035] - [0038] * * N-Cadhedrin comprising HAV motif, conjugated to alginate hydrogel, X-linked. Propagation of pluripotent stem cells from single cells in hydrogel.; paragraph [0044] - paragraph [0051]; figures 2-3, 8 * * Reference to differentiation of hMSC into chondrocyte tissue.; paragraph [0105] *; | [X] - ZHU MEILING ET AL, "Hydrogels functionalized with N-cadherin mimetic peptide enhance osteogenesis of hMSCs by emulating the osteogenic niche", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, (20151102), vol. 77, doi:10.1016/J.BIOMATERIALS.2015.10.072, ISSN 0142-9612, pages 44 - 52, XP029338009 [X] 1-8,10,11,14,15 * abstract * * Osteogenesis of MSC promoted in N-Cadhedrin derived polypetide conjugated to HA crosslinked hydrogel.; page 44, column 2, paragraph 2 - page 45, column 1, paragraph 1; figure 4 * * Materials and Methods 4.1 Macromer sysnthesis and hydrogel preparation 4.2 Cell culture and seeding on hydrogels; page 50, paragraph 4.1 - paragraph 4.2 * DOI: http://dx.doi.org/10.1016/j.biomaterials.2015.10.072 | [X] - SCHENSE J C ET AL, "ENZYMATIC INCORPORATION OF BIOACTIVE PEPTIDES INTO FIBRIN MATRICES ENHANCES NEURITE EXTENSION", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP US, NEW YORK, (20000401), vol. 18, doi:10.1038/74473, ISSN 1087-0156, pages 415 - 419, XP001134964 [X] 1-3,6,7,10-12,14,15 * abstract * * Experimental Protocol Enzymatic crosslinking of HAV motif petides and others in combination using Factor VIII in fibrinogen / thrombin matrix. Outgrowth of neurite from chick embryo dorsal root ganglia; page 418, column 2, paragraph 3 - page 419, column 1, paragraph 1 * DOI: http://dx.doi.org/10.1038/74473 | International search | [X]US2018171286 (BANERJEE IPSITA [US], et al) [X] 1, 3/1, 29 * claims 1-8 *; | [X] - ZHU et al., "Hydrogels functionalized with N-cadherin mimetic peptide enhance osteogenesis of hMSCs by emulating the osteogenic niche", Biomaterials, (20160100), vol. 77, doi:10.1016/j.biomaterials.2015.10.072, pages 44 - 52, XP029338009 [X] 1-3, 29 * ; Abstract, pg 50, col 2 * DOI: http://dx.doi.org/10.1016/j.biomaterials.2015.10.072 | [X] - AN et al., "Hyaluronate-alginate hybrid hydrogels modified with biomimetic peptides for controlling the chondrocyte phenotype", Carbohydr Polym., (20181001), vol. 197, doi:10.1016/j.carbpol.2018.06.016, pages 422 - 430, XP085428072 [X] 1, 3/1, 29 * ; Abstract, pg 423, col 2; pg 425, Fig. 2 and its legend * DOI: http://dx.doi.org/10.1016/j.carbpol.2018.06.016 | [X] - BIAN et al., "Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis", Proc Natl Acad Sci USA, (20130618), vol. 110, no. 25, pages 10117 - 10122, XP055734783 [X] 1-3, 29 * ; Abstract, pg 10121 col 1 * DOI: http://dx.doi.org/10.1073/pnas.1214100110 |