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Extract from the Register of European Patents

EP About this file: EP3929210

EP3929210 - CHIMERIC PROTEIN, METHOD OF PRODUCTION AND USE THEREOF, AND ALSO A NUCLEIC ACID MOLECULE, EXPRESSION CASSETTE, EXPRESSION VECTOR, HOST CELL, COMPOSITION FOR THE DIAGNOSIS OF LEISHMANIASIS, KIT FOR THE DIAGNOSIS OF LEISHMANIASIS AND METHOD OF DIAGNOSIS OF LEISHMANIASIS IN VITRO [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  26.11.2021
Database last updated on 07.10.2024
FormerThe international publication has been made
Status updated on  28.08.2020
Most recent event   Tooltip27.02.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Fundação Oswaldo Cruz
Avenida Brasil 4365
Manguinhos
21045-900 Rio de Janeiro, RJ / BR
[2021/52]
Inventor(s)01 / NETO, Osvaldo, Pompílio, de Melo
Rua Afonso de Albuquerque Melo, Nº420, Apto 802
PE
52060-450 Recife / BR
02 / REZENDE, Antonio, Mauro
Rua Estrada das Ubaias, 200, Apto 1604, Bairro
Casa Forte, PE
52061-080 Recife / BR
03 / TAVARES, Diego, de Hollanda, Cavalcanti
Rua Monsenhor Júlio Maria, nº50, apt. 01,
Madalena, PE
50720-090 Recife / BR
04 / DOS SANTOS, Wagner, José, Tenório
Rua General Polidoro, 380, Várzea, PE
50740-050 Recife / BR
05 / NETO, Artur, Leonel, de Castro
Rua Leonardo Da Vinci, 195, D408, Curado 2, PE
54220-000 Jabotão dos Guararapes / BR
06 / MAGALHÃES, Franklin, Barbalho
Av. Conselheiro Rosa e Silva 999, ap 103, Aflitos
PE
52050-020 Recife / BR
07 / DO NASCIMENTO, Marília, Barbosa
Rua dos Alecrins, nº140, Centro, PE
54759-080 Camaragibe / BR
[N/P]
Former [2021/52]01 / NETO, Osvaldo, Pompílio, de Melo
52060-450 Recife / BR
02 / REZENDE, Antonio, Mauro
52061-080 Recife / BR
03 / TAVARES, Diego, de Hollanda, Cavalcanti
50720-090 Recife / BR
04 / DOS SANTOS, Wagner, José, Tenório
50740-050 Recife / BR
05 / NETO, Artur, Leonel, de Castro
54220-000 Jabotão dos Guararapes / BR
06 / MAGALHÃES, Franklin, Barbalho
52050-020 Recife / BR
07 / DO NASCIMENTO, Marília, Barbosa
54759-080 Camaragibe / BR
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[2021/52]
Application number, filing date20760142.814.02.2020
[2021/52]
WO2020BR50044
Priority number, dateBR2019100363922.02.2019         Original published format: BR102019003639
[2021/52]
Filing languagePT
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020168402
Date:27.08.2020
Language:PT
[2020/35]
Type: A1 Application with search report 
No.:EP3929210
Date:29.12.2021
Language:EN
[2021/52]
Search report(s)International search report - published on:BR27.08.2020
(Supplementary) European search report - dispatched on:EP09.11.2022
ClassificationIPC:A61K39/008, C07K14/44, C12N1/00, C12N15/62, C12N15/63, C12N15/70, G01N33/569
[2022/49]
CPC:
C12N15/70 (EP); G01N33/569 (US); A61K39/008 (EP,US);
C07K14/44 (EP,US); C12N15/63 (EP,US); G01N33/56905 (EP);
C07K2317/24 (US); C07K2319/00 (EP); C07K2319/21 (EP);
G01N2469/20 (EP,US); Y02A50/30 (EP) (-)
Former IPC [2021/52]C07K14/44, C12N15/62, C12N15/63, A61K39/008, C12N1/00, G01N33/569
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/52]
TitleGerman:CHIMÄRES PROTEIN, VERFAHREN ZU SEINER HERSTELLUNG UND SEINE VERWENDUNG, SOWIE EIN NUKLEINSÄUREMOLEKÜL, EXPRESSIONSKASSETTE, EXPRESSIONSVEKTOR, WIRTSZELLE, ZUSAMMENSETZUNG FÜR DIE DIAGNOSE VON LEISHMANIASIS, KIT ZUR DIAGNOSE VON LEISHMANIASIS UND VERFAHREN ZUR DIAGNOSE VON LEISHMANIASIS IN VITRO[2021/52]
English:CHIMERIC PROTEIN, METHOD OF PRODUCTION AND USE THEREOF, AND ALSO A NUCLEIC ACID MOLECULE, EXPRESSION CASSETTE, EXPRESSION VECTOR, HOST CELL, COMPOSITION FOR THE DIAGNOSIS OF LEISHMANIASIS, KIT FOR THE DIAGNOSIS OF LEISHMANIASIS AND METHOD OF DIAGNOSIS OF LEISHMANIASIS IN VITRO[2021/52]
French:PROTÉINE CHIMÈRE, SON PROCÉDÉ DE PRODUCTION ET D'UTILISATION, ET MOLÉCULE D'ACIDE NUCLÉIQUE, CASSETTE D'EXPRESSION, VECTEUR D'EXPRESSION, CELLULE HÔTE, COMPOSITION POUR DIAGNOSTIC DE LEISHMANIOSE, TROUSSE DE DIAGNOSTIC DE LEISHMANIOSE ET MÉTHODE DE DIAGNOSTIC DE LEISHMANIOSE IN VITRO[2021/52]
Entry into regional phase21.09.2021Translation filed 
21.09.2021National basic fee paid 
21.09.2021Search fee paid 
21.09.2021Designation fee(s) paid 
21.09.2021Examination fee paid 
Examination procedure21.09.2021Examination requested  [2021/52]
26.05.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
21.09.2021Renewal fee patent year 03
23.02.2023Renewal fee patent year 04
27.02.2024Renewal fee patent year 05
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Documents cited:Search[X]WO0039298  (LETI LAB [ES], et al) [X] 1-5,7-20* the whole document *;
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 [X]  - BOARINO, A. et al., "Development of recombinant chimeric antigen expressing immunodominant B epitopes of Leishmania infantum for serodiagnosis of visceral leishmaniasis", Clin Diagn Lab Immunol, (20050000), vol. 12, no. 5, doi:10.1128/CDLI.12.5.647-653.2005, pages 647 - 53, XP002547231 [X] 1, 2, 9 a 17 * cited in the description. Abstract, section "Materials and Methods", Figure 1 *

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 [X]  - FARIA, A. R. et al., "Novel recombinant multiepitope proteins for the diagnosis of asymptomatic leishmania infantum-infected dogs", PLoS Negl Trop Dis, (20150000), vol. 9, no. 1, page e3429, XP055506877 [X] 1, 2, 9 and 17 * cited in the description. Abstract, section "Methods", Figure 1. *

DOI:   http://dx.doi.org/10.1039/C5AY00453E
 [X]  - SOTO, M. et al., "Multicomponent chimeric antigen for serodiagnosis of canine visceral leishmaniasis", J Clin Microbiol, (19980000), vol. 36, no. 1, pages 58 - 63, XP002547231 [X] 1, 2, 9 and 17 * . PMCID: PMC124807. cited in the description. Abstract, section "Materials and Methods", Figure 2. *

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 [X]  - DIAS, D. S. et al., "Vaccination with a CD 4+ and CD 8+ T- cell epitopes-based recombinant chimeric protein derived from Leishmania infantum proteins confers protective immunity against visceral leishmaniasis", Transl Res, (20180000), vol. 200, pages 18 - 34, XP085489721 [X] 1, 2, 9 and 17 * Abstract, section "Materials and Methods", Figure 1. *

DOI:   http://dx.doi.org/10.1016/j.trsl.2018.05.001
 [A]  - OLIVEIRA, G. G. et al., "Characterization of novel Leishmania infantum recombinant proteins encoded by genes from five families with distinct capacities for serodiagnosis of canine and human visceral leishmaniasis", Am J Trop Med Hyg., vol. 85, no. 6, page 2011, XP055733941 [A] 1, 2, 9 and 17 * cited in the description. Abstract, Table 1, Figures 1 and 3. *

DOI:   http://dx.doi.org/10.4269/ajtmh.2011.11-0102
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DOI:   http://dx.doi.org/10.1128/CDLI.12.5.647-653.2005
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