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Extract from the Register of European Patents

EP About this file: EP3967698

EP3967698 - SALT AND CRYSTAL FORM OF MTORC1/2 DUAL KINASE ACTIVITY INHIBITOR AND PREPARATION METHOD THEREFOR [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  11.02.2022
Database last updated on 04.06.2024
FormerThe international publication has been made
Status updated on  14.11.2020
Most recent event   Tooltip28.05.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Medshine Discovery Inc.
Room 218, No. 9 Gaoxin Road
Jiangbei New District
Nanjing, Jiangsu 210032 / CN
[2022/11]
Inventor(s)01 / CHEN, Kevin X
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
02 / CHEN, Zhaoguo
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
03 / ZHANG, Li
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
04 / YU, Yanxin
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
05 / ZHOU, Kai
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
06 / JIANG, Fen
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
07 / XIA, Shanghua
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
08 / WANG, Xiaofei
288 Futezhong Road, Pudong New Area
Shanghai 200131 / CN
 [2022/11]
Representative(s)Greaves Brewster LLP
Copa House
Station Road
Cheddar, Somerset BS27 3AH / GB
[2022/11]
Application number, filing date20802767.206.05.2020
[2022/11]
WO2020CN88748
Priority number, dateCN20191037307106.05.2019         Original published format: CN201910373071
CN20191038049108.05.2019         Original published format: CN201910380491
[2022/11]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020224585
Date:12.11.2020
Language:ZH
[2020/46]
Type: A1 Application with search report 
No.:EP3967698
Date:16.03.2022
Language:EN
[2022/11]
Search report(s)International search report - published on:CN12.11.2020
(Supplementary) European search report - dispatched on:EP15.09.2022
ClassificationIPC:C07D519/00, C07D471/04, A61K31/5386, A61K31/5377, A61P35/00, A61P35/02
[2022/11]
CPC:
A61P35/00 (EP); C07D471/04 (EP,US); A61K31/5377 (EP);
A61K31/5386 (EP); A61P35/02 (EP); C07C59/255 (EP);
C07B2200/13 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/11]
TitleGerman:SALZ UND KRISTALLFORM EINES INHIBITORS DER DUALEN KINASEAKTIVITÄT MTORC1/2 UND VERFAHREN ZUR HERSTELLUNG DAVON[2022/11]
English:SALT AND CRYSTAL FORM OF MTORC1/2 DUAL KINASE ACTIVITY INHIBITOR AND PREPARATION METHOD THEREFOR[2022/11]
French:SEL ET FORME CRISTALLINE D'UN INHIBITEUR D'ACTIVITÉ DE DOUBLE KINASE MTORC1/2 ET SON PROCÉDÉ DE PRÉPARATION[2022/11]
Entry into regional phase05.11.2021Translation filed 
01.12.2021National basic fee paid 
01.12.2021Search fee paid 
01.12.2021Designation fee(s) paid 
01.12.2021Examination fee paid 
Examination procedure01.12.2021Examination requested  [2022/11]
10.02.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
27.04.2022Renewal fee patent year 03
26.04.2023Renewal fee patent year 04
27.05.2024Renewal fee patent year 05
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Documents cited:Search   [ ] - No further relevant documents disclosed
International search[A]CN103030653  (SHANGHAI HENGRUI PHARM CO LTD, et al) [A] 1-26* claims 1, 15, description paragraphs [0305]-[0314] *;
 [A]CN103588792  (SHANGHAI INST MATERIA MEDICA, et al) [A] 1-26 * claims 1, 15, description paragraphs [0286]-[0289] *;
 [PX]WO2019085996  (MEDSHINE DISCOVERY INC [CN]) [PX] 1-26 * claims 1, 20, description page 76 lines 13-20 *;
 [A]  - PIKE Kurt G. et al., "Optimization of Potent and Selective Dual mTORC1 and mTORC2 Inhibitors: The Discovery of AZD8055 and AZD2014", Bioorganic & Medicinal Chemistry Letters, (20130118), vol. 23, no. 5, doi:20200612143929, ISSN 1464-3405, XP028976469 [A] 1-26 * page 1214, compound 21 in table 5, page 1215, left-hand column, paragraph 4, page 1216, left-hand column, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2013.01.019
by applicantUS2017281637
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.