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Extract from the Register of European Patents

EP About this file: EP3965832

EP3965832 - COMPOSITIONS AND METHODS FOR TREATING HEPATITIS B [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  11.02.2022
Database last updated on 03.10.2024
FormerThe international publication has been made
Status updated on  20.11.2020
Most recent event   Tooltip30.07.2024Amendment by applicant 
Applicant(s)For all designated states
Beam Therapeutics, Inc.
26 Landsdowne Street 2nd Floor
Cambridge, MA 02139 / US
[2022/11]
Inventor(s)01 / SMEKALOVA, Elena
c/o Beam Therapeutics Inc. 26 Landsdowne St. 2nd.
Floor
Cambridge, Massachusetts 02139 / US
02 / PACKER, Michael
c/o Beam Therapeutics Inc. 26 Landsdowne St. 2nd
Floor
Cambridge, Massachusetts 02139 / US
03 / GREGOIRE, Francine
c/o Beam Therapeutics Inc. 26 Landsdowne St. 2nd
Floor
Cambridge, Massachusetts 02139 / US
04 / BARRERA, Luis
c/o Beam Therapeutics Inc. 26 Landsdowne St. 2nd
Floor
Cambridge, Massachusetts 02139 / US
05 / CIARAMELLA, Giuseppe
c/o Beam Therapeutics Inc. 26 Landsdowne St. 2nd
Floor
Cambridge, Massachusetts 02139 / US
 [2022/11]
Representative(s)Simmons & Simmons LLP (Munich), et al
Lehel Carré
Gewürzmühlstraße 11
80538 Munich / DE
[N/P]
Former [2022/11]Lahrtz, Fritz, et al
Simmons & Simmons LLP
Prinzregentenstraße 68
81675 München / DE
Application number, filing date20806106.908.05.2020
[2022/11]
WO2020US32226
Priority number, dateUS201962846422P10.05.2019         Original published format: US 201962846422 P
US201962927585P29.10.2019         Original published format: US 201962927585 P
[2022/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020231863
Date:19.11.2020
Language:EN
[2020/47]
Type: A1 Application with search report 
No.:EP3965832
Date:16.03.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 19.11.2020 takes the place of the publication of the European patent application.
[2022/11]
Search report(s)International search report - published on:US19.11.2020
(Supplementary) European search report - dispatched on:EP10.01.2024
ClassificationIPC:A61K48/00, C12N15/113, C12N15/85, C12N15/90, C12N15/10, C12N9/22
[2022/11]
CPC:
C12N15/102 (EP,KR,US); A61K31/7088 (KR,US); A61K48/00 (KR);
A61P31/20 (KR,US); C07K14/005 (KR,US); C12N15/113 (EP);
C12N15/1131 (KR,US); C12N15/90 (EP,KR,US); C12N9/22 (EP,US);
C12N9/78 (EP,KR,US); C12Y305/04004 (EP,KR,US); C12Y305/04005 (EP,US);
C07K2319/80 (EP); C12N2310/20 (EP); C12N2730/10121 (KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/11]
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON HEPATITIS B[2022/11]
English:COMPOSITIONS AND METHODS FOR TREATING HEPATITIS B[2022/11]
French:COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE L'HÉPATITE B[2022/11]
Entry into regional phase12.11.2021National basic fee paid 
12.11.2021Search fee paid 
12.11.2021Designation fee(s) paid 
12.11.2021Examination fee paid 
Examination procedure12.11.2021Examination requested  [2022/11]
29.07.2024Amendment by applicant (claims and/or description)
Fees paidRenewal fee
18.07.2022Renewal fee patent year 03
14.03.2023Renewal fee patent year 04
13.03.2024Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.05.202203   M06   Fee paid on   18.07.2022
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Documents cited:Search[XI]WO2018129129  (UNIV RUTGERS [US]) [X] 1,2,8-18,24 * page 43, paragraph 2; claims 1-28 *[I] 1-3,6,8-26;
 [I]  - PENG CHENG ET AL, "CRISPR/Cas9-based tools for targeted genome editing and replication control of HBV", VIROLOGICA SINICA, SPRINGER, DE, vol. 30, no. 5, doi:10.1007/S12250-015-3660-X, ISSN 1674-0769, (20151022), pages 317 - 325, (20151022), XP035577004 [I] 1-3,6,8-26 * the whole document *

DOI:   http://dx.doi.org/10.1007/s12250-015-3660-x
 [I]  - AYMAN EID ET AL, "CRISPR base editors: genome editing without double-stranded breaks", BIOCHEMICAL JOURNAL, GB, (20180611), vol. 475, no. 11, doi:10.1042/BCJ20170793, ISSN 0264-6021, pages 1955 - 1964, XP055638645 [I] 1-3,6,8-26 * the whole document *

DOI:   http://dx.doi.org/10.1042/BCJ20170793
International search[Y]US2018236103  (FRIEDLAND ARI E [US], et al) [Y] 1-3, 38-40, 78-82, 97 * claims 32, 33, 139, 140; para [0034], [0139], [0246] *;
 [Y]WO2019023680  (HARVARD COLLEGE [US], et al) [Y] 1-3, 38-40, 97 * claims 65-67; para [0325], [0677], [0678] *;
 [Y]US2019093099  (LIU DAVID R [US], et al) [Y] 78-82 * claims 307-313; para [0078], [0106], [0236], [0393], [0419]; [0337], Table 27, SEQ ID NO: 703 *;
 [Y]  - KOSTIUSHEV et al., "A novel CRISPR/Cas9-based approach to transient activation of intracellular host restriction factors results in strong suppression of hepatitis B virus and degradation of cccDNA", Journal of Viral Hepatitis, (20180601), vol. 25, pages 16 - 17, XP055761872 [Y] 1-3, 38-40, 78-82, 97 * ; in entirety *
 [XP]  - YANG et al., "Permanent Inactivation of HBV Genomes by CRISPR/Cas9-Mediated Non-cleavage Base Editing", Mol Ther Nucleic Acids, (20200319), vol. 20, pages 480 - 490, XP055761877 [XP] 1-3, 38-40, 78-82, 97 * ; in entirety *

DOI:   http://dx.doi.org/10.1016/j.omtn.2020.03.005
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.