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Extract from the Register of European Patents

EP About this file: EP4004040

EP4004040 - METHODS AND COMPOSITIONS FOR INDUCING NOTCH SIGNALING IN TUMOR MICROENVIRONMENTS [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  29.04.2022
Database last updated on 16.09.2024
FormerThe international publication has been made
Status updated on  05.02.2021
Most recent event   Tooltip29.07.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Fred Hutchinson Cancer Center
1100 Fairview Avenue North
Seattle, WA 98109 / US
[2022/35]
Former [2022/22]For all designated states
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North
Seattle, WA 98109 / US
Inventor(s)01 / BERNSTEIN, Irwin D.
c/o Fred Hutchinson Cancer Research Center 1100
Fairview Avenue North
Seattle, Washington 98109 / US
02 / FURUYAMA, Suzanne
c/o Fred Hutchinson Cancer Research Center 1100
Fairview Avenue North
Seattle, Washington 98109 / US
 [2022/22]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[2022/22]
Application number, filing date20847148.228.07.2020
[2022/22]
WO2020US43900
Priority number, dateUS201962880014P29.07.2019         Original published format: US 201962880014 P
US202063001136P27.03.2020         Original published format: US 202063001136 P
[2022/22]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021021825
Date:04.02.2021
Language:EN
[2021/05]
Type: A1 Application with search report 
No.:EP4004040
Date:01.06.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 04.02.2021 takes the place of the publication of the European patent application.
[2022/22]
Search report(s)International search report - published on:US04.02.2021
(Supplementary) European search report - dispatched on:EP14.07.2023
ClassificationIPC:C07K16/22, A61K39/00, A61P35/00
[2022/22]
CPC:
C07K16/2803 (EP,US); A61P35/00 (EP); C07K14/705 (EP,US);
A61K38/00 (EP); C07K2317/24 (US); C07K2317/55 (US);
C07K2317/622 (US); C07K2317/70 (EP); C07K2317/75 (EP,US);
C07K2317/92 (US); C07K2319/74 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/22]
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN ZUR INDUZIERUNG VON NOTCH-SIGNALISIERUNG IN TUMORMIKROUMGEBUNGEN[2022/22]
English:METHODS AND COMPOSITIONS FOR INDUCING NOTCH SIGNALING IN TUMOR MICROENVIRONMENTS[2022/22]
French:PROCÉDÉS ET COMPOSITIONS PERMETTANT D'INDUIRE UNE SIGNALISATION NOTCH DANS DES MICROENVIRONNEMENTS TUMORAUX[2022/22]
Entry into regional phase16.02.2022National basic fee paid 
16.02.2022Search fee paid 
16.02.2022Designation fee(s) paid 
16.02.2022Examination fee paid 
Examination procedure16.02.2022Examination requested  [2022/22]
08.02.2024Amendment by applicant (claims and/or description)
08.02.2024Date on which the examining division has become responsible
Fees paidRenewal fee
27.07.2022Renewal fee patent year 03
27.07.2023Renewal fee patent year 04
29.07.2024Renewal fee patent year 05
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Documents cited:Search[X]WO2018017827  (HUTCHINSON FRED CANCER RES [US], et al) [X] 1-15 * page 31, line 19 - line 24 *;
 [A]  - OWEN DWIGHT H. ET AL, "DLL3: an emerging target in small cell lung cancer", JOURNAL OF HEMATOLOGY & ONCOLOGY, vol. 12, no. 1, doi:10.1186/s13045-019-0745-2, (20190618), URL: http://link.springer.com/article/10.1186/s13045-019-0745-2/fulltext.html, XP093061358 [A] 1-15 * abstract * * page 2, column l, paragraph 2 * * page 5, column r, paragraph 2 *

DOI:   http://dx.doi.org/10.1186/s13045-019-0745-2
 [A]  - WIERSMA REBECCA E ET AL, "A Novel DLL1-Anti-CD19 Chimeric Protein Effectively Targets Notch Activation to B-Cell Acute Lymphoblastic Leukemia and Induces Cell Death", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (20151203), vol. 126, no. 23, doi:10.1182/BLOOD.V126.23.4833.4833, ISSN 0006-4971, page 4833, XP086647942 [A] 1-15 * Background * * Methods * * Results * * Conclusions *

DOI:   http://dx.doi.org/10.1182/blood.V126.23.4833.4833
International search[Y]US2015259433  (KAHNERT ANTJE [DE], et al) [Y] 40* Especially para [0050] *;
 [Y]US2016009824  (LO KIN-MING [US], et al) [Y] 1-28, 31-33, 37, 39-42 * Especially para [0087], claim 14 *;
 [Y]WO2018017827  (HUTCHINSON FRED CANCER RES [US], et al) [Y] 1-28, 31-33, 37, 39-42 * Especially abstract; pg 4, In 25-28; pg 6, In 1-3, pg 21, In 26-29; pg 2, In 4-5; pg 4 In 9-11, pg 6, In 26-32; pg 2, In 20-21; pg 2, In 20-21, Figs.2A, 2B, 7 *;
 [Y]  - Hossain Fokhrul, Majumder Samarpan, Ucar Deniz A., Rodriguez Paulo C., Golde Todd E., Minter Lisa M., Osborne Barbara A., Miele Lucio, "Notch Signaling in Myeloid Cells as a Regulator of Tumor immune Responses", Front. Immunol., (20180604), vol. 9, page 1288, XP055790932 [Y] 4-17, (18-28, 31-33, 37,39-42)/(4-17) * . Especially abstract; pg 2, col 2, para 1; pg 5, col 2, para 3; pg 4, col 1, para 1; pg 4, col 2, para 2; pg 4, col 1, para 1; pg 5, col 2, para 3 *

DOI:   http://dx.doi.org/10.3389/fimmu.2018.01288
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