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Extract from the Register of European Patents

EP About this file: EP4008005

EP4008005 - METHODS AND SYSTEMS FOR DETECTING MICROSATELLITE INSTABILITY OF A CANCER IN A LIQUID BIOPSY ASSAY [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  06.05.2022
Database last updated on 19.10.2024
FormerThe international publication has been made
Status updated on  05.02.2021
Most recent event   Tooltip05.07.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago, IL 60654 / US
[2024/10]
Former [2022/23]For all designated states
Tempus Labs, Inc.
600 West Chicago Ave., Suite 510
Chicago IL 60654 / US
Inventor(s)01 / LOZAC'HMEUR, Ariane
435 West North Ave, Apt 2
Chicago, IL 60610 / US
02 / KHAN, Aly A.
1437 S. Prairie, Unit: I
Chicago, IL 60605 / US
03 / PERERA, Jason
1009 N Washtenaw Ave., Apt. 1S
Chicago, IL 60622 / US
04 / LAU, Denise
1817 Euclid St., Apt. 1
Santa Monica, CA 90404 / US
05 / HAFEZ, Ashraf
14815 219th Ave NE
Woodinville, WA 98077 / US
 [2022/23]
Representative(s)Grund, Martin, et al
Grund Intellectual Property Group
Patentanwälte und Solicitor PartG mbB
Steinsdorfstraße 2
80538 München / DE
[N/P]
Former [2022/23]Grund, Martin
Grund Intellectual Property Group
Patentanwälte und Solicitor PartG mbB
Steindorfstraße 2
80538 München / DE
Application number, filing date20847239.931.07.2020
[2022/23]
WO2020US44637
Priority number, dateUS201962881845P01.08.2019         Original published format: US 201962881845 P
US201962931600P06.11.2019         Original published format: US 201962931600 P
US202062978130P18.02.2020         Original published format: US 202062978130 P
[2022/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021022225
Date:04.02.2021
Language:EN
[2021/05]
Type: A1 Application with search report 
No.:EP4008005
Date:08.06.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 04.02.2021 takes the place of the publication of the European patent application.
[2022/23]
Search report(s)International search report - published on:US04.02.2021
(Supplementary) European search report - dispatched on:EP30.08.2023
ClassificationIPC:G16B20/00, G16B30/00, G16B40/20, G16H50/30
[2023/39]
CPC:
G16H50/30 (EP); G16B30/10 (US); G16B20/00 (EP);
G16B30/00 (EP); G16B40/00 (US); G16B40/20 (EP)
Former IPC [2022/23]G16B30/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/23]
TitleGerman:VERFAHREN UND SYSTEME ZUM NACHWEIS VON MIKROSATELLITENINSTABILITÄT VON KREBS IN EINEM FLÜSSIGEN BIOPSIETEST[2022/23]
English:METHODS AND SYSTEMS FOR DETECTING MICROSATELLITE INSTABILITY OF A CANCER IN A LIQUID BIOPSY ASSAY[2022/23]
French:PROCÉDÉS ET SYSTÈMES DE DÉTECTION D'INSTABILITÉ DE MICROSATELLITES D'UN CANCER DANS UN DOSAGE DE BIOPSIE LIQUIDE[2022/23]
Entry into regional phase25.02.2022National basic fee paid 
25.02.2022Search fee paid 
25.02.2022Designation fee(s) paid 
25.02.2022Examination fee paid 
Examination procedure25.02.2022Examination requested  [2022/23]
18.03.2024Amendment by applicant (claims and/or description)
18.03.2024Date on which the examining division has become responsible
Fees paidRenewal fee
16.06.2022Renewal fee patent year 03
14.06.2023Renewal fee patent year 04
04.07.2024Renewal fee patent year 05
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Documents cited:Search[A]  - Artyomenko A ET AL, "Microsatellite instability detection with cell-free DNA nextgeneration sequencing", (20181024), URL: https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534(19)49647-6, (20230816), XP093074387 [A] 1-17 * abstract *
 [A]  - ATKINS ALEXANDER ET AL, "Detection of Circulating Tumor DNA with a Single-Molecule Sequencing Analysis Validated for Targeted and Immunotherapy Selection", MOLECULAR DIAGNOSIS AND THERAPY, NZ, (20190617), vol. 23, no. 4, doi:10.1007/s40291-019-00406-0, ISSN 1177-1062, pages 521 - 535, XP055780866 [A] 1-17 * whole document, in particular abstract, paragraphs 2.11.4 and 3.6 *

DOI:   http://dx.doi.org/10.1007/s40291-019-00406-0
 [XP]  - LOZAC'HMEUR A ET AL, "Microsatellite instability detection with cell-free DNA nextgeneration sequencing", EMBASE, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, (20191106), Database accession no. EMB-629890407, XP002809978 [XP] 1-17 * abstract *
    [ ] - JOURNAL FOR IMMUNOTHERAPY OF CANCER 2019 BIOMED CENTRAL LTD. NLD, (2019), vol. 7, no. Supplement 1, ISSN 2051-1426
 [AP]  - Jason Willis ET AL, "Validation of Microsatellite Instability Detection Using a Comprehensive Plasma-Based Genotyping Panel", Clinical cancer research : an official journal of the American Association for Cancer Research, United States, doi:10.1158/1078-0432.CCR-19-1324, (20190804), pages 7035 - 7045, URL: https://clincancerres.aacrjournals.org/content/25/23/7035.full-text.pdf, XP055662308 [AP] 1-17 * whole document, in particular abstract and Materials and methods *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-19-1324
International search[A]WO2019079624  (NANTOMICS LLC [US]) [A] 1-3, 26-30, 48-50, 108-110, 127-129* claim 1; para [0010]; [0011]; [0032]-[0035]; [0043]-[0049] *;
 [X]US2019169685  (GEORGIADIS ANDREW [US], et al) [X] 1-3, 26-30, 48-50, 108- 110, 127-129 * . abstract; para [0008]-[0013]; [0031]; [0049]-[0051]; [0065]; [0073]-[0075] . *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.