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Extract from the Register of European Patents

EP About this file: EP4017857

EP4017857 - METTL16 INHIBITORS AND USES THEREOF [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  27.05.2022
Database last updated on 15.06.2024
FormerThe international publication has been made
Status updated on  26.02.2021
Most recent event   Tooltip03.05.2024New entry: Application deemed to be withdrawn: despatch of communication + time limit 
Applicant(s)For all designated states
City of Hope
1500 E. Duarte Road
Duarte, CA 91010 / US
[2022/26]
Inventor(s)01 / CHEN, Jianjun
1218 S. Fifth Ave
Monrovia, CA 91016 / US
02 / DENG, Xiaolan
1218 S. Fifth Ave
Monrovia, CA 91016 / US
03 / HAN, Li
1218 S. Fifth Ave
Monrovia, CA 91016 / US
04 / LI, Hongzhi
1500 E. Duarte Road
Duarte, CA 91010-3000 / US
05 / SU, Rui
1218 S. Fifth Ave
Monrovia, CA 91016 / US
 [2022/26]
Representative(s)HGF
HGF Limited
1 City Walk
Leeds LS11 9DX / GB
[2022/26]
Application number, filing date20853634.220.08.2020
[2022/26]
WO2020US47185
Priority number, dateUS201962889431P20.08.2019         Original published format: US 201962889431 P
[2022/26]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021035045
Date:25.02.2021
Language:EN
[2021/08]
Type: A1 Application with search report 
No.:EP4017857
Date:29.06.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 25.02.2021 takes the place of the publication of the European patent application.
[2022/26]
Search report(s)International search report - published on:US25.02.2021
(Supplementary) European search report - dispatched on:EP11.09.2023
ClassificationIPC:C07D487/04, A61K31/517, A61P35/00
[2022/26]
CPC:
A61K31/519 (EP,US); A61P35/00 (EP); C07D487/04 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/26]
TitleGerman:METTL16-INHIBITOREN UND VERWENDUNGEN DAVON[2022/26]
English:METTL16 INHIBITORS AND USES THEREOF[2022/26]
French:INHIBITEURS DE METTL 16 ET LEURS UTILISATIONS[2022/26]
Entry into regional phase17.03.2022National basic fee paid 
17.03.2022Search fee paid 
17.03.2022Designation fee(s) paid 
17.03.2022Examination fee paid 
Examination procedure17.03.2022Examination requested  [2022/26]
26.10.2022Amendment by applicant (claims and/or description)
02.05.2024Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
Fees paidRenewal fee
18.07.2022Renewal fee patent year 03
24.08.2023Renewal fee patent year 04
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Documents cited:Search[XI]GB1579678  (AMERICAN HOME PROD) [X] 12,13 * compound 16 table IV, page 29: 4-cyanophenyl is compound E 65796-08-9 compound 8 table I, page 10: 4-chlorobenzyl is compound F 65795-43-9 pharmaceutical compositions in claims 162-164 * [I] 1-15;
 [IP]WO2019226773  (HENRY M JACKSON FOUND ADVANCEMENT MILITARY MEDICINE INC [US]) [IP] 1-15* paragraph [0050] - paragraph [0064] *
International search[XY]US4118561  (LEDIG KURT W) [X] 44-46 * Col 1, In 40-45; Col 3, In 30; Col 4, In 7-8; Col 4, In 22-30 ; Col 4, In 62 to Col 5, Table; Col 6, In 55-64 * [Y] 1-43; 49; 50;
 [A]US2004039000  (GANGJEE ALEEM [US]) [A] 1-50* ENTIRE DOCUMENT *;
 [Y]US2014378486  (XIAO XIANGSHU [US], et al) [Y] 47; 48 * para [0005]; [0017]; [0020]; [0028]; [0050]; pg. 8, Table 4 *;
 [Y]  - IANNIELLO et al., "N6-Methyladenosine (M6A): A Promising New Molecular Target in Acute Myeloid Leukemia", Frontiers in Oncology, (20190409), vol. 9, pages 1 - 11, XP055795614 [Y] 1-43; 49; 50 * . pg. 4, Col 2, para 2; pg. 5, Table 1 *

DOI:   http://dx.doi.org/10.3389/fonc.2019.00251
 [Y]  - WANG et al., "Novel insights on m6A RNA methylation in tumorigenesis: a double-edged sword", Molecular Cancer, (20180000), vol. 17, no. 101, pages 1 - 10, XP055795619 [Y] 47; 48 * . pg. 2, Figure 1; pg. 10, Col 2, para 1 *

DOI:   http://dx.doi.org/10.1186/s12943-018-0847-4
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.