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Extract from the Register of European Patents

EP About this file: EP4024048

EP4024048 - METHOD FOR DIAGNOSING AND TREATING ATHEROSCLEROSIS BY USING NANOVESICLE TARGETING SITE OF CHANGE IN BLOOD FLOW [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  14.06.2024
Database last updated on 26.07.2024
FormerRequest for examination was made
Status updated on  03.06.2022
FormerThe international publication has been made
Status updated on  05.03.2021
Most recent event   Tooltip14.06.2024Application deemed to be withdrawnpublished on 17.07.2024  [2024/29]
Applicant(s)For all designated states
Numais Co., Ltd.
201, 202, 203, 2 FL., SK V1 center II, 31
Gwangnaru-ro 8-gil
Seongdong-gu
Seoul 04799 / KR
[2022/27]
Inventor(s)01 / SUNG, Hak Joon
101-502, 22, Seolleung-ro 126-gil Gangnam-gu
Seoul 06092 / KR
02 / YOON, Jeong Kee
504, 107, Gwanak-ro Gwanak-gu
Seoul 08833 / KR
 [2022/27]
Representative(s)Mathys & Squire
The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2022/27]Miller, David James, et al
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
Application number, filing date20856044.128.08.2020
[2022/27]
WO2020KR11581
Priority number, dateKR2019010721830.08.2019         Original published format: KR 20190107218
[2022/27]
Filing languageKO
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021040473
Date:04.03.2021
Language:KO
[2021/09]
Type: A1 Application with search report 
No.:EP4024048
Date:06.07.2022
Language:EN
[2022/27]
Search report(s)International search report - published on:KR04.03.2021
(Supplementary) European search report - dispatched on:EP17.11.2023
ClassificationIPC:G01N33/554, G01N33/68, A61K35/28, A61K38/17, A61P9/10, C07K7/08
[2022/27]
CPC:
G01N33/6893 (EP,KR,US); G01N33/554 (KR,US); C12N5/0607 (EP,US);
A61K35/28 (EP,KR,US); A61K38/177 (KR,US); A61P9/10 (EP,KR,US);
C07K7/08 (EP,KR,US); C12N5/0663 (EP,US); A61K38/00 (EP);
C07K2319/02 (KR); C07K2319/03 (EP,KR); C07K7/06 (EP);
C12N2501/65 (EP); C12N2503/00 (EP); G01N2800/323 (EP,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/27]
TitleGerman:VERFAHREN ZUR DIAGNOSE UND BEHANDLUNG VON ATHEROSKLEROSE DURCH VERWENDUNG EINER NANOVESIKEL-ZIELSTELLE ZUR VERÄNDERUNG DES BLUTFLUSSES[2022/27]
English:METHOD FOR DIAGNOSING AND TREATING ATHEROSCLEROSIS BY USING NANOVESICLE TARGETING SITE OF CHANGE IN BLOOD FLOW[2022/27]
French:MÉTHODE DE DIAGNOSTIC ET DE TRAITEMENT DE L'ATHÉROSCLÉROSE À L'AIDE D'UN SITE DE CIBLAGE DE NANOVÉSICULE DANS LE FLUX SANGUIN[2022/27]
Entry into regional phase18.03.2022Translation filed 
18.03.2022National basic fee paid 
18.03.2022Search fee paid 
18.03.2022Designation fee(s) paid 
18.03.2022Examination fee paid 
Examination procedure18.03.2022Amendment by applicant (claims and/or description)
18.03.2022Examination requested  [2022/27]
01.03.2024Application deemed to be withdrawn, date of legal effect  [2024/29]
22.03.2024Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2024/29]
Fees paidRenewal fee
25.08.2022Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.08.202304   M06   Not yet paid
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Documents cited:Search[A]WO2018004143  (AMOREPACIFIC CORP [KR], et al) [A] 1-10;
 [I]  - HOFMEISTER LUCAS H. ET AL, "Phage-Display-Guided Nanocarrier Targeting to Atheroprone Vasculature", ACS NANO, US, vol. 9, no. 4, doi:10.1021/acsnano.5b01048, ISSN 1936-0851, (20150313), pages 4435 - 4446, URL: https://pubs.acs.org/doi/abs/10.1021/acsnano.5b01048, XP055787394 [I] 1-10 * abstract, table 1 *

DOI:   http://dx.doi.org/10.1021/acsnano.5b01048
 [A]  - FUJITA YU ET AL, "Clinical Application of Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapeutics for Inflammatory Lung Diseases", JOURNAL OF CLINICAL MEDICINE, CH, vol. 7, no. 10, doi:10.3390/jcm7100355, ISSN 2077-0383, (20181001), pages 1 - 21, URL: https://www.mdpi.com/2077-0383/7/10/355, XP055787398 [A] 1-10

DOI:   http://dx.doi.org/10.3390/jcm7100355
 [A]  - CONSUELO MERINO-GONZÁLEZ ET AL, "Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Angiogenesis: Potencial Clinical Application", FRONTIERS IN PHYSIOLOGY, CH, (20160209), vol. 7, doi:10.3389/fphys.2016.00024, ISSN 1664-042X, XP055398494 [A] 1-10

DOI:   http://dx.doi.org/10.3389/fphys.2016.00024
 [A]  - ARSALAN SHABBIR ET AL, "Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro", STEM CELLS AND DEVELOPMENT, US, (20150715), vol. 24, no. 14, doi:10.1089/scd.2014.0316, ISSN 1547-3287, pages 1635 - 1647, XP055583096 [A] 1-10

DOI:   http://dx.doi.org/10.1089/scd.2014.0316
International search[A]KR20180003322  (AMOREPACIFIC CORP [KR], et al) [A] 1-8,11* See entire document. *;
 [AY]  - Hofmeister Lucas H., Lee Sue Hyun, Norlander Allison E., Montaniel Kim Ramil C., Chen Wei, Harrison David G., Sung Hak-Joon ACS Nano, "Phage-Display-Guided Nanocarrier Targeting to Atheroprone Vasculature", ACS Nano, (20150313), vol. 9, no. 4, doi:10.1021/acsnano.5b01048, pages 4435 - 4446, XP055787394 [A] 3,4,6 * See abstract; pages 4436-4438 and 4442-4444; and table 1. * [Y] 1,2,5,7,8,11

DOI:   http://dx.doi.org/10.1021/acsnano.5b01048
 [Y]  - Fujita Yu, Kadota Tsukasa, Araya Jun, Ochiya Takahiro, Kuwano Kazuyoshi, "Clinical Application of Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapeutics for Inflammatory Lung Diseases", Journal of Clinical Medicine, (20181014), vol. 7, no. 10, doi:10.3390/jcm7100355, pages 1 - 21, XP055787398 [Y] 1,2,5,7,8,11 * See abstract; and pages 3, 5, 6 and 14. *

DOI:   http://dx.doi.org/10.3390/jcm7100355
 [A]  - Kelley William J., Safari Hanieh, Lopez-Cazares Genesis, Eniola-Adefeso Omolola, "Vascular‐targeted nanocarriers: design considerations and strategies for successful treatment of atherosclerosis and other vascular diseases", Nanomedicine and Nanobiotechnology, United States, (20160519), vol. 8, no. 6, doi:10.1002/wnan.1414, ISSN 1939-5116, pages 909 - 926, XP055787402 [A] 1-8,11 * See entire document. *

DOI:   http://dx.doi.org/10.1002/wnan.1414
 [A]  - Gupta Mukesh K., Lee Yunki, Boire Timothy C., Lee Jung-Bok, Kim Won Shik, Sung Hak-Joon, "Recent strategies to design vascular theranostic nanoparticles", Nanotheranostics, (20170406), vol. 1, no. 2, doi:10.7150/ntno.18531, ISSN 2206-7418, pages 166 - 177, XP055787408 [A] 1-8,11 * See entire document. *

DOI:   http://dx.doi.org/10.7150/ntno.18531
by applicant   - SEI, Y. J. et al., Sci Rep, (20170000), vol. 7, page 10019
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.