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EP4051698
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EP About this file: EP4051698
| EP4051698 - COMPOSITIONS AND METHODS FOR TREATING SENSORINEURAL HEARING LOSS USING OTOFERLIN DUAL VECTOR SYSTEMS [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 05.08.2022 Database last updated on 15.06.2024 | |
| Former | The international publication has been made Status updated on 10.05.2021 | Most recent event Tooltip | 29.02.2024 | Supplementary search report | published on 27.03.2024 [2024/13] | Applicant(s) | For all designated states Decibel Therapeutics, Inc. 1325 Boylston Street, Suite 500 Boston, MA 02215 / US | For all designated states Regeneron Pharmaceuticals, Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | [2022/36] | Inventor(s) | 01 /
BURNS, Joseph 1325 Boylston St Suite 500 Boston, MA 02215 / US | 02 /
ELLIS, Kathryn 1325 Boylston St Suite 500 Boston, MA 02215 / US | 03 /
GIBSON, Tyler 1325 Boylston St Suite 500 Boston, MA 02215 / US | 04 /
PALERMO, Adam 1325 Boylston St Suite 500 Boston, MA 02215 / US | 05 /
SCHWANDER, Martin 1325 Boylston St Suite 500 Boston, MA 02215 / US | 06 /
WHITTON, Jonathon 1325 Boylston St Suite 500 Boston, MA 02215 / US | 07 /
SABIN, Leah C/o Regeneron Pharmaceuticals, Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | 08 /
KYRATSOUS, Christos C/o Regeneron Pharmaceuticals, Inc 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | 09 /
DRUMMOND SAMUELSON, Meghan C/o Regeneron Pharmaceuticals, Inc 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | [2022/36] | Representative(s) | Hoffmann Eitle Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München / DE | [2022/36] | Application number, filing date | 20883297.2 | 30.10.2020 | [2022/36] | WO2020US58265 | Priority number, date | US201962928290P | 30.10.2019 Original published format: US 201962928290 P | US202062965776P | 24.01.2020 Original published format: US 202062965776 P | US202062971504P | 07.02.2020 Original published format: US 202062971504 P | US202063023058P | 11.05.2020 Original published format: US 202063023058 P | [2022/36] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2021087296 | Date: | 06.05.2021 | Language: | EN | [2021/18] | Type: | A1 Application with search report | No.: | EP4051698 | Date: | 07.09.2022 | Language: | EN | The application published by WIPO in one of the EPO official languages on 06.05.2021 takes the place of the publication of the European patent application. | [2022/36] | Search report(s) | International search report - published on: | US | 06.05.2021 | (Supplementary) European search report - dispatched on: | EP | 28.02.2024 | Classification | IPC: | C07K14/47, C12N15/63, C12N15/86 | [2022/36] | CPC: |
C07K14/705 (EP,IL,KR);
C12N15/86 (EP,IL,KR,US);
A61K48/0075 (EP,IL,KR,US);
A61K48/005 (EP,IL,KR);
A61P27/16 (KR);
C07K14/4716 (EP,IL,KR,US);
A01K2217/075 (EP,IL);
A01K2227/105 (EP,IL,US);
A01K2267/0306 (EP,IL,US);
C12N2750/14143 (EP,IL,KR,US);
C12N2800/40 (EP,IL,KR,US);
C12N2830/008 (EP,IL,KR,US);
C12N2840/44 (EP,IL,KR,US)
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| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2022/36] | Title | German: | ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON SENSORINEURALEM HÖRVERLUST UNTER VERWENDUNG VON OTOFERLIN-DOPPELVEKTORSYSTEMEN | [2022/36] | English: | COMPOSITIONS AND METHODS FOR TREATING SENSORINEURAL HEARING LOSS USING OTOFERLIN DUAL VECTOR SYSTEMS | [2022/36] | French: | COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE LA SURDITÉ NEUROSENSORIELLE À L'AIDE DE SYSTÈMES À DEUX VECTEURS POUR L'OTOFERLINE | [2022/36] | Entry into regional phase | 13.05.2022 | National basic fee paid | 13.05.2022 | Search fee paid | 13.05.2022 | Designation fee(s) paid | 13.05.2022 | Examination fee paid | Examination procedure | 13.05.2022 | Examination requested [2022/36] | 19.12.2022 | Amendment by applicant (claims and/or description) | Fees paid | Renewal fee | 27.10.2022 | Renewal fee patent year 03 | 27.10.2023 | Renewal fee patent year 04 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]WO2017100791 (MASSACHUSETTS EYE & EAR INFIRMARY [US], et al) [A] 1-15 * Whole doc., in partic. p.16-19; claim 17 *; | [IP]WO2019210181 (DECIBEL THERAPEUTICS INC [US]) [IP] 1-15* Whole doc., in partic. p.3, 16-22,29-30; Examples 1 and 2 *; | [XP]US2020155705 (BURNS JOSEPH [US], et al) [XP] 1-15 * Whole doc., in partic. para. [0175,0178,0192-0205]; Seq. ID No.5 *; | [A] - E. CABERLOTTO ET AL, "Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20110321), vol. 108, no. 14, doi:10.1073/pnas.1017114108, ISSN 0027-8424, pages 5825 - 5830, XP055647801 [A] 1-15 * p.5827, col.1, 1st para. in partic. * DOI: http://dx.doi.org/10.1073/pnas.1017114108 | [A] - CABERLOTTO E. ET AL, "Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia; Supporting Information", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 108, no. 14, doi:10.1073/pnas.1017114108, ISSN 0027-8424, (20110405), pages 5825 - 5830, URL: https://www.pnas.org/highwire/filestream/605692/field_highwire_adjunct_files/0/pnas.201017114SI.pdf, XP055867195 [A] 1-15 * Fig. S1C in partic. * DOI: http://dx.doi.org/10.1073/pnas.1017114108 | [A] - CORNS LAURA F. ET AL, "Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation", NATURE COMMUNICATIONS, UK, vol. 9, no. 1, doi:10.1038/s41467-018-06307-w, ISSN 2041-1723, (20181001), URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167318/pdf/41467_2018_Article_6307.pdf, XP093133183 [A] 1-15 * p.3, col.1 * DOI: http://dx.doi.org/10.1038/s41467-018-06307-w | International search | [Y]WO2018039375 (AKOUOS INC [US], et al) [Y] 1-3, 29, 32, 33 * entire document *; | [Y]WO2018204734 (UNIV FLORIDA [US], et al) [Y] 29, 32, 33 * entire document *; | [A]WO2019165292 (AKOUOS INC [US], et al) [A] 1-3, 28-33* entire document *; | [PX]WO2020163743 (DECIBEL THERAPEUTICS INC [US], et al) [PX] 1-3, 28-33 * entire document *; | [Y] - MICHALSKI et al., "Genetics of auditory mechano-electrical transduction", Pflugers Archives, (20140625), vol. 467, doi:10.1007/s00424-014-1552-9, pages 49 - 72, XP035416827 [Y] 1-3, 29, 32, 33 * . entire document * DOI: http://dx.doi.org/10.1007/s00424-014-1552-9 | [Y] - SKARNES et al., "A conditional knockout resource for the genome-wide study of mouse gene function", Nature, (20110615), vol. 474, no. 7351, doi:10.1038/nature10163, pages 337 - 342, XP009157945 [Y] 3 * . entire document * DOI: http://dx.doi.org/10.1038/nature10163 |