blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP4060023

EP4060023 - METHOD FOR DIRECT TRANSDIFFERENTIATION OF SOMATIC CELL [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  19.08.2022
Database last updated on 17.07.2024
FormerThe international publication has been made
Status updated on  21.05.2021
Most recent event   Tooltip20.06.2024Change - representative 
Applicant(s)For all designated states
Juntendo Educational Foundation
2-1-1, Hongo
Bunkyo-ku
Tokyo 113-8421 / JP
[2022/38]
Inventor(s)01 / OKAZAKI, Yasushi
c/o Juntendo University,
2-1-1, Hongo, Bunkyo-ku
Tokyo 113-8421 / JP
02 / MATSUMOTO, Masahito
c/o Juntendo University,
2-1-1, Hongo, Bunkyo-ku
Tokyo 113-8421 / JP
03 / HAGIWARA, Hiroko
c/o Juntendo University,
2-1-1, Hongo, Bunkyo-ku
Tokyo 113-8421 / JP
 [2022/38]
Representative(s)Wächtershäuser & Hartz Patentanwaltspartnerschaft mbB
Weinstraße 8
80333 München / DE
[N/P]
Former [2022/38]Schiener, Jens
Wächtershäuser & Hartz
Patentanwaltspartnerschaft mbB
Weinstraße 8
80333 München / DE
Application number, filing date20886657.412.11.2020
[2022/38]
WO2020JP42289
Priority number, dateJP2019020501512.11.2019         Original published format: JP 2019205015
[2022/38]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021095811
Date:20.05.2021
Language:JA
[2021/20]
Type: A1 Application with search report 
No.:EP4060023
Date:21.09.2022
Language:EN
[2022/38]
Search report(s)International search report - published on:JP20.05.2021
(Supplementary) European search report - dispatched on:EP14.11.2023
ClassificationIPC:C12N5/071, C12N5/077, C12N5/0775, C12N5/078, C12N5/079, C12N5/10, C12N15/12, C07K14/47, C12N5/0793
[2023/50]
CPC:
C07K14/4702 (EP); C12N5/067 (EP,US); C12N15/907 (US);
C12N5/0619 (EP,US); C12N5/0653 (EP,US); C12N5/0654 (EP,US);
C12N5/0657 (EP,US); C12N2500/02 (US); C12N2501/11 (EP,US);
C12N2501/115 (EP,US); C12N2501/119 (US); C12N2501/12 (EP,US);
C12N2501/165 (EP,US); C12N2501/33 (US); C12N2501/392 (EP);
C12N2501/60 (EP); C12N2506/1307 (EP); C12N2506/1353 (EP,US);
C12N2510/00 (EP); C12N5/0622 (EP) (-)
Former IPC [2022/38]C12N5/071, C12N5/077, C12N5/0775, C12N5/078, C12N5/079, C12N5/10, C12N15/12
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/38]
TitleGerman:VERFAHREN ZUR DIREKTEN TRANSDIFFERENZIERUNG EINER SOMATISCHEN ZELLE[2022/38]
English:METHOD FOR DIRECT TRANSDIFFERENTIATION OF SOMATIC CELL[2022/38]
French:PROCÉDÉ DE TRANSDIFFÉRENCIATION DIRECTE DE CELLULE SOMATIQUE[2022/38]
Entry into regional phase20.05.2022Translation filed 
20.05.2022National basic fee paid 
20.05.2022Search fee paid 
20.05.2022Designation fee(s) paid 
20.05.2022Examination fee paid 
Examination procedure20.05.2022Examination requested  [2022/38]
29.05.2024Amendment by applicant (claims and/or description)
29.05.2024Date on which the examining division has become responsible
Fees paidRenewal fee
30.11.2022Renewal fee patent year 03
29.11.2023Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XI]US2016160180  (YAMAMOTO KENTA [JP], et al) [X] 10-12,14 * Items 1-6; paragraphs [0019] - [0024]; figure 31 * * Osteoblast transdifferentiation from fibroblast.; paragraph [0052]; figure 31 * * Oct4LMGlis1 One preferred gene combination; paragraph [0119] * [I] 13;
 [XI]US2017002319  (D'ALESSIO ANA C [US], et al) [X] 10-12,14 * paragraphs [0029] - [0030]; claim 15; table 1 * * paragraph [0163]; figure Fig4B; table 8 * [I] 13;
 [XI]US2018312812  (MATSUMOTO MASAHITO [JP], et al) [X] 10-12,14 * Points 1 and 2 of paragraph [0010]; paragraphs [0009] - [0012] - [ 0280]; figures 1-8; claims 1-14 * [I] 13;
 [X]  - MOMOKO MAEKAWA ET AL, "Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1", CLEO: APPLICATIONS AND TECHNOLOGY 2019 SAN JOSE, CALIFORNIA UNITED STATES 5-10 MAY 2019, (20110601), vol. 474, no. 7350, doi:10.1038/nature10106, pages 225 - 229, XP055572349 [X] 10,14 * abstract *

DOI:   http://dx.doi.org/10.1038/nature10106
 [A]  - MASAMITSU KONNO ET AL, "Adipose-derived mesenchymal stem cells and regenerative medicine", DEVELOPMENT GROWTH AND DIFFERENTIATION, RICHMOND, VIC. : BLACKWELL PUBL. ASIA, US, (20130303), vol. 55, no. 3, doi:10.1111/DGD.12049, ISSN 0012-1592, pages 309 - 318, XP071144107 [A] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1111/dgd.12049
International search[XA]WO2015012377  (KYOTO PREFECTURAL PUBLIC UNIV CORP [JP]) [X] 1, 3-4, 6-12 * claims, examples, fig. 2, 27 entire text * [A] 2, 5, 13-14;
 [XA]US2017002319  (D'ALESSIO ANA C [US], et al) [X] 2, 6, 8, 10,12-13 * claims, paragraphs [0080], [0164]-[0214], fig. 4, entire text * [A] 1, 3-5, 7, 9,11, 14;
 [XYA]WO2017073740  (UNIV SAITAMA MEDICAL [JP]) [X] 8, 10 * claims, paragraph [0040], examples claims, paragraph [0040], examples entire text * [Y] 2-6, 8, 10, 12-13 [A] 1, 7, 9, 11, 14;
 [XA]JP2018108080  (KYOTO PREFECTURAL PUBLIC UNIV CORP) [X] 10-12 * claims, examples, fig. 2-3, 8 entire text * [A] 1-9, 13-14;
 [A]  - CHAO, J. R. et al., "Human retinal pigment epithelial cells prefer praline as a nutrient and transport metabolic intermediates to the retinal side", J. Biol. Chem., (20170804), vol. 292, no. 31, pages 12895 - 12905, XP055823712 [A] 1-14 * , page 12902, left column, lines 29-31 *
 [YA]  - SUI, L. et al., "Role of EMP signaling in pancreatic progenitor differentiation from human embryonic stem cells", Stem Cell Rev. Rep., (20130307), vol. 9, no. 5, pages 569 - 577, XP055823716 [Y] 2-6, 8, 10, 12-13 * , page 569, abstract, page 570, left column, line 4 from the bottom to page 570, right column, line 17, page 571, right column, line 9 from the bottom to page 572, right column, line 8 entire text * [A] 1, 7, 9, 11, 14

DOI:   http://dx.doi.org/10.1007/s12015-013-9435-6
 [A]  - MAEKAWA, M. et al., "Direct reprogramming of somatic cells is promoted by maternal transcription factor Glisl", Nature, (20110000), vol. 474, no. 7350, doi:10.1038/nature10106, pages 225 - 229, XP055572349 [A] 1-14 * , entire text *

DOI:   http://dx.doi.org/10.1038/nature10106
 [A]  - YASUOKA, Y. et al., "Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis", Mol. Biol. Evol., (20190905), vol. 37, no. 1, pages 100 - 109, XP055823720 [A] 1-14 * , entire text *

DOI:   http://dx.doi.org/10.1093/molbev/msz205
by applicantWO2007069666
 JP2009533047
 JP2013519371
 WO2016002937
 WO2017073740
    - "NCBI", Database accession no. NM 147193
    - KARLIN, S.ALTSCHUL, S.F., Proc. Natl. Acad. Sci. USA, (19900000), vol. 87, pages 2264 - 2268
    - ALTSCHUL, S.F., Proc. Natl. Acad. Sci. USA, vol. 90, page 5873
    - Cell, (20060000), vol. 126, pages 663 - 676
    - Cell, (20070000), vol. 131, pages 861 - 872
    - Science, (20070000), vol. 318, pages 1917 - 1920
    - Science, (20080000), vol. 322, pages 949 - 953
    - Science, (20090000), vol. 324, pages 797 - 801
    - Biochemical and Biophysical Research Communications, (20120000), vol. 426, pages 141 - 147
 WO2007069666
 JP2009533047
 JP2013519371
 WO2016002937
 WO2017073740
    - KARLIN, S.ALTSCHUL, S.F., Proc. Natl. Acad. Sci. USA, (19900000), vol. 87, pages 2264 - 2268
    - ALTSCHUL, S.F., Proc. Natl. Acad. Sci. USA, vol. 90, page 5873
    - Cell, (20060000), vol. 126, pages 663 - 676
    - Cell, (20070000), vol. 131, pages 861 - 872
    - Science, (20070000), vol. 318, pages 1917 - 1920
    - Science, (20080000), vol. 322, pages 949 - 953
    - Science, (20090000), vol. 324, pages 797 - 801
    - Biochemical and Biophysical Research Communications, (20120000), vol. 426, pages 141 - 147
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.