blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP4065593

EP4065593 - ON-LINE ULTRA PERFORMANCE HYDROPHOBIC INTERACTION CHROMATOGRAPHY FOR MONITORING AT LEAST ONE PRODUCT ATTRIBUTE [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  02.09.2022
Database last updated on 02.09.2024
FormerThe international publication has been made
Status updated on  04.06.2021
Most recent event   Tooltip02.03.2024Supplementary search reportpublished on 03.04.2024  [2024/14]
Applicant(s)For all designated states
Merck Sharp & Dohme LLC
126 East Lincoln Avenue
Rahway, New Jersey 07065-0907 / US
[2022/40]
Inventor(s)01 / BROWER, Mark, A.
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
02 / DESAI, Jayesh
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
03 / DOS SANTOS PINTO, Nuno Jorge
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
04 / DUNN, Zachary, D.
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
05 / GOSPODAREK, Adrian
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
06 / HUA, Xiaoqing
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
07 / PATEL, Bhumit, A.
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
08 / RICHARDSON, Douglas, D. II
770 Sumneytown Pike
West Point, Pennsylvania 19486 / US
 [2022/40]
Representative(s)Merck Sharp & Dohme LLC
120 Moorgate
London EC2M 6UR / GB
[N/P]
Former [2022/40]Hussain, Deeba, et al
Merck Sharp & Dohme Corp.
120 Moorgate
London, EC2M 6UR / GB
Application number, filing date20893866.220.11.2020
[2022/40]
WO2020US61435
Priority number, dateUS201962940588P26.11.2019         Original published format: US 201962940588 P
US202062981707P26.02.2020         Original published format: US 202062981707 P
[2022/40]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021108237
Date:03.06.2021
Language:EN
[2021/22]
Type: A1 Application with search report 
No.:EP4065593
Date:05.10.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 03.06.2021 takes the place of the publication of the European patent application.
[2022/40]
Search report(s)International search report - published on:US03.06.2021
(Supplementary) European search report - dispatched on:EP01.03.2024
ClassificationIPC:C07K1/20, G01N30/88
[2024/14]
CPC:
C07K1/20 (EP); G01N30/88 (EP,US); G01N30/14 (US);
G01N30/24 (US); G01N2030/027 (US); G01N2030/8831 (EP,US);
G01N2030/8886 (EP) (-)
Former IPC [2022/40]C07K1/20
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/40]
TitleGerman:ULTRALEISTUNGSSTARKE HYDROPHOBE ONLINE-INTERAKTIONSCHROMATOGRAFIE ZUR ÜBERWACHUNG MINDESTENS EINES PRODUKTMERKMALS[2022/40]
English:ON-LINE ULTRA PERFORMANCE HYDROPHOBIC INTERACTION CHROMATOGRAPHY FOR MONITORING AT LEAST ONE PRODUCT ATTRIBUTE[2022/40]
French:CHROMATOGRAPHIE D'INTERACTION HYDROPHOBE À ULTRA-PERFORMANCE EN LIGNE POUR SURVEILLER AU MOINS UN ATTRIBUT DE PRODUIT[2022/40]
Entry into regional phase27.06.2022National basic fee paid 
27.06.2022Search fee paid 
27.06.2022Designation fee(s) paid 
27.06.2022Examination fee paid 
Examination procedure27.06.2022Examination requested  [2022/40]
Fees paidRenewal fee
10.11.2022Renewal fee patent year 03
14.11.2023Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[I]  - WEI BINGCHUAN ET AL, "Native Hydrophobic Interaction Chromatography Hyphenated to Mass Spectrometry for Characterization of Monoclonal Antibody Minor Variants", ANALYTICAL CHEMISTRY, US, (20191120), vol. 91, no. 24, doi:10.1021/acs.analchem.9b04467, ISSN 0003-2700, pages 15360 - 15364, XP093130724 [I] 1-15 * abstract * * page 15360 - page 15361 * * page 15363, paragraph last *

DOI:   http://dx.doi.org/10.1021/acs.analchem.9b04467
 [I]  - FEKETE SZABOLCS ET AL, "Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, ELSEVIER B.V, AMSTERDAM, NL, (20160404), vol. 130, doi:10.1016/J.JPBA.2016.04.004, ISSN 0731-7085, pages 3 - 18, XP029761128 [I] 1-15 * abstract * * page 3 * * 4. Application of HIC for protein separation; page 10 - page 13 *

DOI:   http://dx.doi.org/10.1016/j.jpba.2016.04.004
International search[A]US2005161399  (DILLON THOMAS [US], et al) [A] 1-6 * , entire document *;
 [A]US2012309040  (MADIAN ASHRAF G [US], et al) [A] 1-6 * , entire document *;
 [A]US2019242877  (WANG SHUNHAI [US], et al) [A] 1-6 * , entire document *;
 [XE]WO2020247790  (AMGEN INC [US]) [XE] 1-6* , entire document *;
 [X]  - HAVERICK et al., "Separation of mAbs molecular variants by analytical hydrophobic interaction chromatography HPLC", mAbs, (20140000), vol. 6, no. 4, doi:10.4161/mabs.28693, pages 852 - 858, XP055407190 [X] 1-6 * , entire document esp pg 852-853 *

DOI:   http://dx.doi.org/10.4161/mabs.28693
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.