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EP4088727
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EP About this file: EP4088727
| EP4088727 - ANTI-GLYCATION COMPOSITIONS [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 13.03.2026 Database last updated on 18.03.2026 | |
| Former | Request for examination was made Status updated on 19.05.2023 | ||
| Former | The application has been published Status updated on 14.10.2022 | Most recent event Tooltip | 13.03.2026 | Application deemed to be withdrawn | published on 15.04.2026 [2026/16] | Applicant(s) | For all designated states AHAVA - DEAD SEA LABORATORIES LTD. 1 Arava St. P.O.B. 109 7015002 Lod / IL | [2022/46] | Inventor(s) | 01 /
Cohen, Dror 8698000 D.N the Dead Sea / IL | 02 /
Portugal Cohen, Meital 9641210 Jerusalem / IL | 03 /
Blinderman, Alexandra 9066500 M.P. Arvot Ha Yarden / IL | 04 /
Barak, David 7177709 Modi'in / IL | 05 /
Ze'evi, Ma'or 9066600 Dead Sea D.N Arvot Hayarden / IL | [2022/46] | Representative(s) | Vossius & Partner Patentanwälte Rechtsanwälte mbB Siebertstraße 3 81675 München / DE | [2022/46] | Application number, filing date | 21176839.5 | 31.05.2021 | [2022/46] | Priority number, date | US202117319446 | 13.05.2021 Original published format: US202117319446 | [2022/46] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP4088727 | Date: | 16.11.2022 | Language: | EN | [2022/46] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 29.11.2021 | Classification | IPC: | A61K33/00, A61K36/28, A61K36/77, A61P17/00 | [2022/46] | CPC: |
A61P17/00 (EP,CN,IL);
A61K35/08 (IL,US);
A61K8/9789 (CN,IL,US);
A61K33/00 (EP,IL);
A61K33/06 (EP,IL);
A61K33/22 (EP,IL);
A61K33/24 (EP,IL);
A61K35/02 (CN);
A61K36/28 (EP,CN,IL,US);
A61K36/324 (EP,IL);
A61K36/328 (CN,IL,US);
A61K36/725 (CN,IL,US);
A61K36/77 (EP,IL);
A61K8/965 (CN,IL,US);
A61P17/18 (CN);
| C-Set: |
A61K33/00, A61K2300/00 (EP);
A61K33/06, A61K2300/00 (EP);
A61K33/22, A61K2300/00 (EP);
A61K33/24, A61K2300/00 (EP);
A61K35/02, A61K2300/00 (CN);
A61K36/28, A61K2300/00 (EP,CN);
A61K36/324, A61K2300/00 (EP);
A61K36/328, A61K2300/00 (CN); | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2023/25] |
| Former [2022/46] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | KH | Not yet paid | MA | Not yet paid | MD | Not yet paid | TN | Not yet paid | Title | German: | ANTIGLYKIERUNGZUSAMMENSETZUNGEN | [2022/46] | English: | ANTI-GLYCATION COMPOSITIONS | [2022/46] | French: | COMPOSITIONS ANTI-GLYCATION | [2022/46] | Examination procedure | 12.05.2023 | Amendment by applicant (claims and/or description) | 12.05.2023 | Examination requested [2023/25] | 12.05.2023 | Date on which the examining division has become responsible | 02.12.2025 | Application deemed to be withdrawn, date of legal effect [2026/16] | 17.12.2025 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2026/16] | Fees paid | Renewal fee | 21.03.2023 | Renewal fee patent year 03 | 13.03.2024 | Renewal fee patent year 04 | Penalty fee | Additional fee for renewal fee | 31.05.2025 | 05 M06 Not yet paid |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [XY] RU2228771 | [Y] EP2174648 (AHAVA DEAD SEA LAB LTD et al.) | [Y] IL232044 | [XY] DATABASE WPI Week 200443, Derwent World Patents Index; AN 2004-459431, XP002804757 | by applicant | TWI469778 | US2013078202 | US6871805 | US10722461 | US2007203240 | US10512603 | RU2253433 | EP1074245 | US2006002929 | US2003049255 | EA033620 | US2003007939 | US6800292 | US2009093440 | WO02069963 | US2008044373 | US2020214955 | US10842733 | JP2002370963 | JP2002212046 | WO2015030702 | US9511034 | US8846019 | EP3398585 | US7435432 | US7666442 | US2011044920 | NARDA, M.PENO-MAZZARINO, L.KRUTMANN, J.TRULLAS, C.GRANGER, C.: "Novel Facial Cream Containing Carnosine Inhibits Formation of Advanced Glycation End-Products in Human Skin", SKIN PHARMACOLOGY AND PHYSIOLOGY, vol. 31, no. 6, 2018, pages 324 - 331 | SHIN, S.LEE, J.-A.KIM, M.KUM, H.JUNG, E.PARK, D.: "Anti-glycation activities of phenolic constituents from Silybum marianum (Milk Thistle) flower in vitro and on human explants", MOLECULES, vol. 20, no. 3, 2015, pages 3549 - 3564, XP055245503, DOI: 10.3390/molecules20033549 DOI: http://dx.doi.org/10.3390/molecules20033549 | DAVE CHANDLER: "Effects of plant-derived polyphenols on TNF-alpha and nitric oxide production induced by advanced glycation end products", MOL. NUTR. FOOD RES., vol. 54, 2010, pages S141 - S150 | CHI-HAO WU: "Silymarin: a novel antioxidant with antiglycation and anti-inflammatory properties in vitro and in vivo", ANTIOXID. REDOX. SIGNAL., vol. 14, 2011, pages 353 - 366 | AHMED ALHUSBAN: "Silymarin Ameliorates Diabetes-Induced Proangiogenic Response in Brain Endothelial Cells through a GSK-3(3 Inhibition-Induced Reduction of VEGF Release", J. DIABETES RES., 25 October 2017 (2017-10-25), pages 2537216 | SAURABH AWASTHIAN. T. SARASWATHI.: "Silybin, a flavonolignan from milk thistle seeds, restrains the early and advanced glycation end product modification of albumin", RSC ADV, vol. 5, 2015, pages 87660 - 87666 | PORTUGAL-COHEN, M.COHEN, D.ISH-SHALOM, E.LAOR-COSTA, Y.MA'OR, Z. E.: "Dead Sea minerals: New findings on skin and the biology beyond", EXPERIMENTAL DERMATOLOGY, vol. 28, no. 5, 2019, pages 585 - 592 | JESSICA V. VALENCIA: "Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics", ANALYTICAL BIOCHEMISTRY, vol. 324, 2004, pages 68 - 78, XP004476319, DOI: 10.1016/j.ab.2003.09.013 DOI: http://dx.doi.org/10.1016/j.ab.2003.09.013 | G.B. SAJITHLAL: "Advanced glycation end products induce crosslinking of collagen in vitro", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1407, 1998, pages 215 - 224, XP004276781, DOI: 10.1016/S0925-4439(98)00043-X DOI: http://dx.doi.org/10.1016/S0925-4439(98)00043-X | HUANG, D.OU, B.HAMPSCH-WOODILL, M.FLANAGAN, J. A.PRIOR, R. L.: "High-throughput assay of oxygen radical absorbance capacity (ORAC) using a multichannel liquid handling system coupled with a microplate fluorescence reader in 96-well format", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 50, no. 16, 2002, pages 443 - 4444 |