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Extract from the Register of European Patents

EP About this file: EP4122467

EP4122467 - THX-B FOR TREATING AND PREVENTING CANCER AND METASTASIS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  01.12.2023
Database last updated on 13.07.2024
FormerThe application has been published
Status updated on  23.12.2022
Most recent event   Tooltip01.12.2023Application deemed to be withdrawnpublished on 03.01.2024  [2024/01]
Applicant(s)For all designated states
Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO)
Melchor Fernández Almagro, 3
28029 Madrid / ES
For all designated states
Saragovi, Horacio Uri
3421 Marlowe Avenue
Montréal, Québec H4A 3L8 / CA
[2023/04]
Inventor(s)01 / SARAGOVI, Horacio Uri
Montreal, Québec H4A3L8 / CA
02 / PEINADO SELGAS, Héctor
28029 Madrid / ES
03 / GARCÍA SILVA, Susana
28029 Madrid / ES
04 / NOGUÉS VERA, Laura
28029 Madrid / ES
05 / HERNÁNDEZ BARRANCO, Alberto
28029 Madrid / ES
 [2023/04]
Representative(s)Elzaburu S.L.P.
Edificio Torre de Cristal
Paseo de la Castellana 259 C, planta 28
28046 Madrid / ES
[2023/04]
Application number, filing date21382669.622.07.2021
[2023/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP4122467
Date:25.01.2023
Language:EN
[2023/04]
Search report(s)(Supplementary) European search report - dispatched on:EP22.02.2022
ClassificationIPC:A61K31/522, A61K45/06, A61P35/00, A61P35/04, G01N33/50
[2023/04]
CPC:
A61K31/522 (EP); A61K39/39558 (EP); A61K45/06 (EP);
A61P35/00 (EP); A61P35/04 (EP); C07K16/2827 (EP);
G01N33/5743 (EP); G01N2333/82 (EP); G01N2800/54 (EP) (-)
C-Set:
A61K31/522, A61K2300/00 (EP);
A61K39/39558, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/04]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:THX-B ZUR BEHANDLUNG UND VORBEUGUNG VON KREBS UND METASTASEN[2023/04]
English:THX-B FOR TREATING AND PREVENTING CANCER AND METASTASIS[2023/04]
French:THX-B POUR LE TRAITEMENT ET LA PRÉVENTION DU CANCER ET DES MÉTASTASES[2023/04]
Examination procedure19.10.2021Loss of particular rights, legal effect: Claims
02.11.2021Despatch of communication of loss of particular rights: Claims {1}
26.07.2023Application deemed to be withdrawn, date of legal effect  [2024/01]
16.08.2023Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2024/01]
Fees paidPenalty fee
Additional fee for renewal fee
31.07.202303   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XDY]WO2011041453  (UNIV LELAND STANFORD JUNIOR [US], et al) [XD] 9-12 * example 1; claims 1-9,16 * [Y] 5,6;
 [XI]WO2012048417  (SARAGOVI HORACIO URI [CA], et al) [X] 1-5,13 * page 1, paragraph 1 * * page 5; compound (Ib) * * page 10, paragraph l * * page 11, paragraph 1 * * page 19; table 1; compounds I-B * * page 29, paragraph 2 * * page 30, paragraph 1; example -; claims 1,3,13,17 * * page 25, paragraph 2 - page 28, paragraph 1 * [I] 7,8;
 [Y]  - VIDAL ANNA ET AL, "Decoding the Role of CD271 in Melanoma", CANCERS, vol. 12, no. 9, doi:10.3390/cancers12092460, (20200831), page 2460, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564075/pdf/cancers-12-02460.pdf, XP055890310 [Y] 5,6 * whole document and more particularly page 12, point 8 *

DOI:   http://dx.doi.org/10.3390/cancers12092460
 [X]  - BERETTI F ET AL, "CD271 is expressed in melanomas with more aggressive behaviour, with correlation of characteristic morphology by in vivo reflectance confocal microscopy", BRITISH JOURNAL OF DERMATOLOGY, JOHN WILEY, HOBOKEN, USA, (20150122), vol. 172, no. 3, doi:10.1111/BJD.13301, ISSN 0007-0963, pages 662 - 668, XP071158886 [X] 9-12 * the whole document *

DOI:   http://dx.doi.org/10.1111/bjd.13301
 [X]  - Guo Ruifeng ET AL, "Original Article Increased expression of melanoma stem cell marker CD271 in metastatic melanoma to the brain", Int J Clin Exp Pathol, (20140101), URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313973/pdf/ijcep0007-8947.pdf, (20220210), XP055890389 [X] 9-12 * the whole document *
 [A]  - María Platón-Corchado ET AL, "p75NTR antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa", Cell Death and Disease (2017), (20170713), URL: https://www.nature.com/articles/cddis2017306.pdf, (20220210), XP055890305 [A] 1-14 * the whole document *
 [T]  - GARCÍA-SILVA SUSANA ET AL, "Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism", NATURE CANCER, vol. 2, no. 12, doi:10.1038/s43018-021-00272-y, (20211201), pages 1387 - 1405, URL: https://www.nature.com/articles/s43018-021-00272-y.pdf, XP055890412 [T] 1-14 * the whole document *

DOI:   http://dx.doi.org/10.1038/s43018-021-00272-y
by applicantWO2011041453
 US9296691
 AU2019203598
    - VIDAL, A. et al., Cancers, (20200000), vol. 12, page 2460
    - ZHONG, M. et al., FEBS Open Bio, (20200000), vol. 2021, pages 226 - 236
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.