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Extract from the Register of European Patents

EP About this file: EP4182024

EP4182024 - USE OF CANNABIDIOL IN THE TREATMENT OF SEIZURES ASSOCIATED WITH MUTATIONS IN THE SYNGAP1 GENE [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  15.03.2024
Database last updated on 11.09.2024
FormerRequest for examination was made
Status updated on  21.04.2023
FormerThe international publication has been made
Status updated on  28.01.2022
Formerunknown
Status updated on  16.08.2021
Most recent event   Tooltip09.07.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
GW Research Limited
Sovereign House Vision Park
Chivers Way
Histon
Cambridge, Cambridgeshire CB24 9BZ / GB
[2023/21]
Inventor(s)01 / CHECKETTS, Daniel, Adam
Cambridge Cambridgeshire CB24 9BZ / GB
02 / CRAIG, Kevin, James
Cambridge Cambridgeshire CB24 9BZ / GB
 [2023/21]
Representative(s)HGF
HGF Limited
1 City Walk
Leeds LS11 9DX / GB
[2023/21]
Application number, filing date21751515.415.07.2021
[2023/21]
WO2021EP69877
Priority number, dateGB2020001117520.07.2020         Original published format: GB 202011175
[2023/21]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022017942
Date:27.01.2022
Language:EN
[2022/04]
Type: A1 Application with search report 
No.:EP4182024
Date:24.05.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 27.01.2022 takes the place of the publication of the European patent application.
[2023/21]
Search report(s)International search report - published on:EP27.01.2022
ClassificationIPC:A61P25/08, A61K45/00, A61K31/05, A61K31/19, A61K31/352
[2023/21]
CPC:
A61P25/08 (EP,GB,US); A61K31/05 (EP,GB); A61K31/658 (US);
A61K31/185 (US); A61K31/19 (EP); A61K31/352 (EP);
A61K31/53 (US); A61K36/185 (GB); A61K45/00 (EP);
A61K45/06 (US); A61P25/10 (GB) (-)
C-Set:
A61K31/05, A61K2300/00 (EP);
A61K31/19, A61K2300/00 (EP);
A61K31/352, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/21]
TitleGerman:VERWENDUNG VON CANNABIDIOL BEI DER BEHANDLUNG VON ANFÄLLEN IM ZUSAMMENHANG MIT MUTATIONEN IM SYNGAP1-GEN[2023/21]
English:USE OF CANNABIDIOL IN THE TREATMENT OF SEIZURES ASSOCIATED WITH MUTATIONS IN THE SYNGAP1 GENE[2023/21]
French:UTILISATION DE CANNABIDIOL DANS LE TRAITEMENT DE CRISES ASSOCIÉES À DES MUTATIONS DANS LE GÈNE SYNGAP1[2023/21]
Entry into regional phase16.02.2023National basic fee paid 
16.02.2023Designation fee(s) paid 
16.02.2023Examination fee paid 
Examination procedure16.02.2023Examination requested  [2023/21]
16.02.2023Date on which the examining division has become responsible
05.09.2023Amendment by applicant (claims and/or description)
18.03.2024Despatch of a communication from the examining division (Time limit: M06)
Fees paidRenewal fee
24.07.2023Renewal fee patent year 03
09.07.2024Renewal fee patent year 04
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Cited inInternational search[Y]US2017231923  (GUY GEOFFREY [GB], et al) [Y] 1-14 * paragraphs [0002] , [0 99] * * claims 1-22 *;
 [Y]WO2019207319  (GW RES LTD [GB]) [Y] 1-14 * claims 1-43 *;
 [XPYI]WO2021055499  (ZYNERBA PHARMACEUTICALS INC [US]) [XP] 14 * claims 1-17 * * example 2; tables 2, 5 * [Y] 1-14[I] 1-14;
 [XYI]  - KUCHENBUCH MATHIEU ET AL, "Add-on cannabidiol significantly decreases seizures in 3 patients with SYNGAP1 developmental and epileptic encephalopathy", EPILEPSIA OPEN, vol. 5, no. 3, doi:10.1002/epi4.12411, ISSN 2470-9239, (20200604), pages 496 - 500, URL: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/epi4.12411, XP055847803 [X] 14 * abstract * * figure 1; table 1 * * 4. Discussion * [Y] 1-14 [I] 1-14

DOI:   http://dx.doi.org/10.1002/epi4.12411
 [XYI]  - VLASKAMP DANIQUE R.M. ET AL, "SYNGAP1 encephalopathy. A distinctive generalized developmental and epileptic encephalopathy", NEUROLOGY, US, vol. 92, no. 2, doi:10.1212/WNL.0000000000006729, ISSN 0028-3878, (20190108), pages e96 - e107, URL: https://n.neurology.org/content/neurology/92/2/e96.full.pdf, XP055808006 [X] 14 * page e102, section "Epilepsy treatment and outcome";; figure 5 * [Y] 1-14 [I] 1-14

DOI:   http://dx.doi.org/10.1212/WNL.0000000000006729
by applicant   - ROGER PERTWEE, Handbook of Cannabis, pages 3 - 15
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.