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Extract from the Register of European Patents

EP About this file: EP4103692

EP4103692 - NOVEL TDZD ANALOGS AS AGENTS THAT DELAY, PREVENT, OR REVERSE AGE-ASSOCIATED DISEASES; AND AS ANTI-CANCER AND ANTILEUKEMIC AGENTS [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  18.11.2022
Database last updated on 24.08.2024
FormerThe international publication has been made
Status updated on  20.08.2021
Most recent event   Tooltip01.05.2024Supplementary search reportpublished on 29.05.2024  [2024/22]
Applicant(s)For all designated states
Bowroju, Suresh, Kuarm
325 Jack Stephens Dr.
Uams Biomed-i
Little Rock, AR 72205 / US
For all designated states
Crooks, Peter
22 Ridgefield Cove
Little Rock, AZ 72223 / US
For all designated states
Penthalla, Narsimha
1300 Westhampton Drive
Little Rock, AZ 72211 / US
For all designated states
Ayyadevara, Srinivas
14203 Overcreek Pass
Little Rock, AZ 72211 / US
For all designated states
Guzman, Monica
450E 63rd St. Apartment 11a
New York, NY 10065 / US
For all designated states
Shmookler Reis, Robert, J.
14 Pinnacle View Cove
Little Rock, AZ 72223 / US
For all designated states
Lopes, Eloisi
413 East 69th Street
New York, NY 10021 / US
For all designated states
Kakraba, Samuel
629 Jack Stephens Drive
Little Rock, AZ 72205 / US
[2022/51]
Inventor(s)01 / see applicant
...
 [2022/51]
Representative(s)CH Kilger Anwaltspartnerschaft mbB
Fasanenstraße 29
10719 Berlin / DE
[2022/51]
Application number, filing date21754449.312.02.2021
[2022/51]
WO2021US17970
Priority number, dateUS202062976604P14.02.2020         Original published format: US 202062976604 P
[2022/51]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2021163572
Date:19.08.2021
Language:EN
[2021/33]
Type: A1 Application with search report 
No.:EP4103692
Date:21.12.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 19.08.2021 takes the place of the publication of the European patent application.
[2022/51]
Search report(s)International search report - published on:US19.08.2021
(Supplementary) European search report - dispatched on:EP30.04.2024
ClassificationIPC:C12N5/071, C12N5/077, C12N5/0775
[2022/51]
CPC:
C07D417/12 (EP,US); C07D285/08 (EP,US); A61P25/28 (US);
A61P29/00 (EP); A61P35/00 (EP); A61P35/02 (US);
C07D493/04 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/51]
TitleGerman:NEUARTIGE TDZD-ANALOGE ALS MITTEL ZUR VERZÖGERUNG, VORBEUGUNG ODER UMKEHRUNG VON ALTERSBEDINGTEN KRANKHEITEN SOWIE ALS MITTEL GEGEN KREBS UND LEUKÄMIE[2022/51]
English:NOVEL TDZD ANALOGS AS AGENTS THAT DELAY, PREVENT, OR REVERSE AGE-ASSOCIATED DISEASES; AND AS ANTI-CANCER AND ANTILEUKEMIC AGENTS[2022/51]
French:NOUVEAUX ANALOGUES DE TDZD EN TANT QU'AGENTS QUI RETARDENT, PRÉVIENNENT OU INVERSENT DES MALADIES ASSOCIÉES À L'ÂGE; ET EN TANT QU'AGENTS ANTICANCÉREUX ET ANTILEUCÉMIQUES[2022/51]
Entry into regional phase14.09.2022National basic fee paid 
14.09.2022Search fee paid 
14.09.2022Designation fee(s) paid 
14.09.2022Examination fee paid 
Examination procedure14.09.2022Examination requested  [2022/51]
06.04.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
09.02.2023Renewal fee patent year 03
13.02.2024Renewal fee patent year 04
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Cited inInternational search[A]WO2005024755  (DECIPHERA PHARMACEUTICALS LLC [US], et al) [A] 1,4-6,13,18,20,39-76* , especially: pg 51, In 25-35, Example 78. *;
 [A]  - Jessica Nicole Ponder, "Phenotypic Screening of Parthenolide Derivatives Reveals the Chemoprotective Role of Galectin-1 in Acute Myeloid Leukemia", Thesis, (20180101), ISBN 978-0-438-00313-2, pages 1 - 240, XP055847532 [A] 1,4-6,13,18,20,39-76 * , BSK 1-40. *
 [A]  - Anna Martinez , Mercedes Alonso , Ana Castro , Concepcion Perez , Francisco J Moreno, "First Non-ATP Competitive Glycogen Synthase Kinase 3-beta (GSK-3-beta) Inhibitors: Thiadiazolidinones (TDZD) as Potential Drugs for the Treatment of Alzheimer's Disease", Journal of Medicinal Chemistry, US, (20020101), vol. 45, no. 6, doi:10.1021/jm011020u, ISSN 0022-2623, pages 1292 - 1299, XP002292084 [A] 1,4-6,13,18,20,39-76 * , especially: pg 1294, Table 1, compound 14. *

DOI:   http://dx.doi.org/10.1021/jm011020u
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.