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Extract from the Register of European Patents

EP About this file: EP4188349

EP4188349 - COMPOSITIONS COMPRISING THYMOL AND AMINO ACIDS FOR USE IN THE TREATMENT OF INFLAMMATORY OR FUNCTIONAL INTESTINAL DISORDERS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  01.03.2024
Database last updated on 03.10.2024
FormerRequest for examination was made
Status updated on  05.05.2023
FormerThe international publication has been made
Status updated on  04.02.2022
Formerunknown
Status updated on  03.09.2021
Most recent event   Tooltip17.07.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Vetagro International S.r.l.
Via Ignazio Porro 2
42124 Reggio Emilia (RE) / IT
[2023/23]
Inventor(s)01 / PIVA, Andrea
42124 Reggio nell'Emilia / IT
02 / GRILLI, Ester
42124 Reggio nell'Emilia / IT
 [2023/23]
Representative(s)Benedetto, Marco
Marben S.r.l.
Via Larga, 16
20122 Milano / IT
[2023/23]
Application number, filing date21759132.026.07.2021
[2023/23]
WO2021IB56723
Priority number, dateIT2020001891331.07.2020         Original published format: IT202000018913
[2023/23]
Filing languageIT
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022023932
Date:03.02.2022
Language:EN
[2022/05]
Type: A1 Application with search report 
No.:EP4188349
Date:07.06.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 03.02.2022 takes the place of the publication of the European patent application.
[2023/23]
Search report(s)International search report - published on:EP03.02.2022
ClassificationIPC:A61K31/055, A23K20/142, A23K20/158, A23K50/30, A23L33/175, A61K9/16, A61K31/198, A61K31/405, A61P1/00, A61P1/06, A61P1/08, A61P1/10, A61P1/12, A61P1/14
[2023/23]
CPC:
A61P1/06 (EP); A61K31/05 (US); A23K10/30 (US);
A23K20/105 (EP); A23K20/111 (EP); A23K20/142 (EP);
A23K50/30 (EP); A23K50/60 (EP); A23K50/75 (EP);
A23K50/80 (EP); A23L33/175 (EP); A61K31/055 (EP);
A61K31/198 (EP); A61K31/405 (EP,US); A61K45/06 (US);
A61K9/0056 (EP); A61K9/1617 (EP); A61K9/1664 (EP);
A61P1/00 (EP); A61P1/08 (EP); A61P1/10 (EP);
A61P1/12 (EP); A61P1/14 (EP); A61P29/00 (US);
B65B63/08 (EP); B65B9/02 (EP); Y02A40/818 (EP) (-)
C-Set:
A61K31/055, A61K2300/00 (EP);
A61K31/198, A61K2300/00 (EP);
A61K31/405, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/23]
TitleGerman:ZUSAMMENSETZUNGEN MIT THYMOL UND AMINOSÄUREN ZUR VERWENDUNG BEI DER BEHANDLUNG VON ENTZÜNDLICHEN ODER FUNKTIONELLEN DARMERKRANKUNGEN[2023/23]
English:COMPOSITIONS COMPRISING THYMOL AND AMINO ACIDS FOR USE IN THE TREATMENT OF INFLAMMATORY OR FUNCTIONAL INTESTINAL DISORDERS[2023/23]
French:COMPOSITIONS COMPRENANT DU THYMOL ET DES ACIDES AMINÉS POUR UNE UTILISATION DANS LE TRAITEMENT DE TROUBLES INTESTINAUX INFLAMMATOIRES OU FONCTIONNELS[2023/23]
Entry into regional phase02.02.2023National basic fee paid 
02.02.2023Designation fee(s) paid 
02.02.2023Examination fee paid 
Examination procedure02.02.2023Examination requested  [2023/23]
02.02.2023Date on which the examining division has become responsible
15.09.2023Amendment by applicant (claims and/or description)
29.02.2024Despatch of a communication from the examining division (Time limit: M04)
27.06.2024Reply to a communication from the examining division
Fees paidRenewal fee
28.07.2023Renewal fee patent year 03
17.07.2024Renewal fee patent year 04
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Cited inInternational search[A]US2013323352  (MERCIER YVES [FR], et al) [A] 1,8,9 * page 1, paragraphs [0008], [0012]-[0015], [0019], [0027] * * page 2, paragraphs [0029]-[0031], [0035]-[0039], [0056] * * claims 1, 4-5, 15 *;
 [Y]WO2018089516  (UNIV NORTH CAROLINA STATE [US], et al) [Y] 1-9 * page 2, paragraph [0005]; claims 1-3, 8-10 * * page 5, paragraph [0023] * * pages 12-13; example 2 *;
 [Y]CN111406835  (UNIV FOSHAN) [Y] 1-9 * example 5 * * claims 1, 4 *;
 [Y]WO2020146587  (NOVUS INT INC [US]) [Y] 9 * pages 23-24, paragraph [0080] * * page 32; example 1 * * claims 1, 5, 9, 11, 13, 14, 20, 21 *;
 [XP]WO2021019510  (VETAGRO INT S R L [IT]) [XP] 1-7,9 * page 9, lines 29-32 * * pages 27-29; example - * * claims 1-16 *;
 [XP]WO2021019506  (VETAGRO INT S R L [IT]) [XP] 1-7,9 * page 7, paragraph 2 * * page 11, paragraph 2 * * pages 30-32; example - ** claims 1-16 *;
 [A]  - DU ENCUN ET AL, "Effects of thymol and carvacrol supplementation on intestinal integrity and immune responses of broiler chickens challenged with Clostridium perfringens", vol. 7, no. 1, doi:10.1186/s40104-016-0079-7, (20161201), JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, URL: https://jasbsci.biomedcentral.com/track/pdf/10.1186/s40104-016-0079-7.pdf, XP055810404 [A] 1-4,9 * abstract * * page 2, column 2, paragraph 2 * * page 3; table 2 * * page 6, column 2, paragraph 1 * * page 7, column 1, paragraph 2 * * page 9, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1186/s40104-016-0079-7
 [Y]  - Pourya Tahmasebi ET AL, "Thymol has beneficial effects on the experimental model of ulcerative colitis", Avicenna journal of phytomedicine, doi:10.22038/AJP.2019.13383, (20191101), pages 538 - 550, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823534/pdf/AJP-9-538.pdf, XP055762265 [Y] 1-9 * abstract *

DOI:   http://dx.doi.org/10.22038/AJP.2019.13383
 [Y]  - FAITH A. OMONIJO ET AL, "Development of Novel Microparticles for Effective Delivery of Thymol and Lauric Acid to Pig Intestinal Tract", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, US, (20180824), vol. 66, no. 37, doi:10.1021/acs.jafc.8b02808, ISSN 0021-8561, pages 9608 - 9615, XP055652012 [Y] 1-9 * abstract * * page 9609, column 1, paragraph 2 * * page 9609, column 2, paragraph 2 * * page 9611, column 2, paragraph 2 * * page 9612; figure 5 * * page 9612, column 1, paragraph 2 - column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1021/acs.jafc.8b02808
 [Y]  - JANGHAN CHOI ET AL, "Evaluation of lipid matrix microencapsulation for intestinal delivery of thymol in weaned pigs", TRANSLATIONAL ANIMAL SCIENCE, (20191122), vol. 4, no. 1, doi:10.1093/tas/txz176, pages 411 - 422, XP055762300 [Y] 1-9 * abstract * * Materials; page 412 * * page 415; table 2 * * page 419, column 1, paragraph 2 * * page 419, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1093/tas/txz176
 [Y]  - LIU YULAN ET AL, "Roles of amino acids in preventing and treating intestinal diseases: recent studies with pig models", AMINO ACIDS, SPRINGER VERLAG, AU, vol. 49, no. 8, doi:10.1007/S00726-017-2450-1, ISSN 0939-4451, (20170614), pages 1277 - 1291, (20170614), XP037121510 [Y] 1-9 * abstract * * page 1278, column 1, paragraph 3 - column 2, paragraph 1 * * page 1281, column 2, paragraph 1 * * page 1285, column 1, paragraph 2 * * page 1285, column 2, paragraph l - page 1286, column 1, paragraph 2 * * page 1286, column 2, paragraph 3 - page 1287, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1007/s00726-017-2450-1
 [Y]  - ZHANG BEIBEI ET AL, "Dietary L-arginine inhibits intestinal Clostridium perfringens colonisation and attenuates intestinal mucosal injury in broiler chickens", vol. 118, no. 5, doi:10.1017/S0007114517002094, ISSN 0007-1145, (20170913), pages 321 - 332, BRITISH JOURNAL OF NUTRITION, URL: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/dietary-larginine-inhibits-intestinal-clostridium-perfringens-colonisation-and-attenuates-intestinal-mucosal-injury-in-broiler-chickens/4C025930CA1940D794FBF7D20395D1E6, XP055810405 [Y] 1-9 * abstract * * page 321, column 1, paragraph 1 * * page 321, column 2, paragraph 2 - page 322, column 1 * * page 330, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1017/S0007114517002094
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