blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP4288455

EP4288455 - BINDING AGENTS AND METHODS OF USING THE SAME [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  10.11.2023
Database last updated on 15.06.2024
FormerThe international publication has been made
Status updated on  12.08.2022
Formerunknown
Status updated on  05.03.2022
Most recent event   Tooltip05.04.2024Change: Validation statespublished on 08.05.2024  [2024/19]
05.04.2024Change - extension statespublished on 08.05.2024  [2024/19]
Applicant(s)For all designated states
Mozart Therapeutics, Inc.
500 Fairview Avenue, Suite 600
Seattle, Washington 98109 / US
[2023/50]
Inventor(s)01 / CRANE, Courtney
Seattle, Washington 98109 / US
02 / SWIDEREK, Kristine
Seattle, Washington 98109 / US
03 / JULIEN, Susan
Seattle, Washington 98109 / US
 [2023/50]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2023/50]
Application number, filing date22705939.102.02.2022
[2023/50]
WO2022US14881
Priority number, dateUS202163145394P03.02.2021         Original published format: US 202163145394 P
US202163148016P10.02.2021         Original published format: US 202163148016 P
US202163161325P15.03.2021         Original published format: US 202163161325 P
US202163209949P11.06.2021         Original published format: US 202163209949 P
US202263298028P10.01.2022         Original published format: US 202263298028 P
[2023/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022169825
Date:11.08.2022
Language:EN
[2022/32]
Type: A1 Application with search report 
No.:EP4288455
Date:13.12.2023
Language:EN
The application published by WIPO in one of the EPO official languages on 11.08.2022 takes the place of the publication of the European patent application.
[2023/50]
Search report(s)International search report - published on:EP11.08.2022
ClassificationIPC:C07K16/28, A61P37/06
[2023/50]
CPC:
C07K16/2815 (EP,IL,KR,US); A61P35/00 (US); A61P37/06 (EP,IL,KR,US);
C07K16/2803 (EP,IL,KR,US); A61K2039/505 (KR,US); C07K2317/31 (EP,IL,KR,US);
C07K2317/526 (EP,IL,KR); C07K2317/74 (US); C07K2317/76 (EP,IL,KR,US);
C07K2317/92 (EP,IL,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/50]
TitleGerman:BINDEMITTEL UND VERFAHREN ZUR VERWENDUNG DAVON[2023/50]
English:BINDING AGENTS AND METHODS OF USING THE SAME[2023/50]
French:AGENTS DE LIAISON ET LEURS MÉTHODES D'UTILISATION[2023/50]
Entry into regional phase23.08.2023National basic fee paid 
23.08.2023Designation fee(s) paid 
23.08.2023Examination fee paid 
Examination procedure23.08.2023Examination requested  [2023/50]
23.08.2023Date on which the examining division has become responsible
02.04.2024Amendment by applicant (claims and/or description)
Fees paidRenewal fee
27.02.2024Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[A]WO2012160448  (INNATE PHARMA SA [FR], et al) [A] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * paragraphs [0025] - [0027] - [0061] , [0 64] , [0 65] , [0 76] - [0078] - [0 80] , [0 81] , [0089] , [0180] , [0594]; examples 1-4; sequences 1,2 *;
 [A]WO2014066532  (BRISTOL MYERS SQUIBB CO [US], et al) [A] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * page 3, line 14 - page 4, line 7 * * page 14, line 1 - page 15, line 13 * * page 17, line 5 - line 10; examples 1-5,8,10,11 *;
 [AD]WO2014164553  (IMAGINAB INC [US]) [AD] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * paragraphs [0001] - [0008] - [0 11] , [0 79] , [ 107] - [0111] - [0114] - [0117] - [0172] , [0193] , [0200]; figures 12D, 12G; examples 4-10, 14-16,20; sequences 42, 48 *;
 [I]WO2016196912  (DANA FARBER CANCER INST INC [US]) [I] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * page 2, line 23 - page 3, line 22 * * page 4, line 3 - line 6 * * page 19, line 31 - page 22, line 13 * * example 11; claims 9-13, 22-26 *;
 [A]WO2019032661  (ORIONIS BIOSCIENCES INC [US], et al) [A] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * page 45, line 14 - line 26 * * page 46, line 25 - page 47, line 16 * * page 48, line 33 - page 49, line 31 * * page 55, line 13 - line 25 * * page 88, line 6 - line 30 * * page 90, line 16 - line 22 *;
 [AP]WO2021026233  (UNIV LELAND STANFORD JUNIOR [US]) [AP] 1-8,12-14,27-54,60-83,89-113,119-142,148-161* paragraphs [0009] - [0012] - [0 37] , [0 38]; example 2 *;
 [A]  - SALIGRAMA NARESHA ET AL, "Opposing T cell responses in experimental autoimmune encephalomyelitis", NATURE, NATURE PUBLISHING GROUP UK, LONDON, vol. 572, no. 7770, doi:10.1038/S41586-019-1467-X, ISSN 0028-0836, (20190807), pages 481 - 487, (20190807), XP036867488 [A] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * the whole document, in particular page 484, right-hand column, 2nd paragraph - page 485, left-hand column, first paragraph and figure 6 *

DOI:   http://dx.doi.org/10.1038/s41586-019-1467-x
 [A]  - PENDE DANIELA, "Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation", FRONT. IMMUNOL., (20190528), vol. 10, no. Article 1179, doi:https://doi.org/10.3389/fimmu.2019.01179, pages 1 - 18, XP055918423 [A] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * the whole document *

DOI:   http://dx.doi.org/https://doi.org/10.3389/fimmu.2019.01179
 [A]  - LOURDES GIMENO ET AL, "KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling", CANCERS, (20201015), vol. 12, doi:10.3390/cancers12102991, pages 1 - 20, XP055918429 [A] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * the whole document, in particular page 3, second paragraph *

DOI:   http://dx.doi.org/
 [AP]  - MISHRA SHRUTI ET AL, "CD8+ Regulatory T Cell - A Mystery to Be Revealed", FRONT. IMMUNOL., (20211018), vol. 12, no. Article 708874, doi:https://doi.org/10.3389/fimmu.2021.708874, pages 1 - 7, XP055918437 [AP] 1-8,12-14,27-54,60-83,89-113,119-142,148-161 * the whole document, in particular page 2, left-hand column, second paragraph - right-hand column, last paragraph *

DOI:   http://dx.doi.org/https://doi.org/10.3389/fimmu.2021.708874
by applicantUS4518584
 WO8702671
 US4676980
 US4704692
 US4737462
 US4946778
 WO9308829
 US5500362
 US5731168
 US5770387
 US5821337
 US5885573
 US5929212
 WO9951642
 US6080560
 US6194551
 WO0129242
 US2001018041
 US2002168362
 US6512162
 US2003031668
 US2003167531
 US2003232009
 US6737056
 US2004132028
 WO2004056312
 WO2004106381
 WO2005061547
 US2005158305
 WO2005100402
 US2005266001
 WO2006003179
 US2006025576
 WO2006029879
 EP1691833
 US2006270045
 WO2007024715
 WO2007042261
 US7250297
 US2007224633
 US7332581
 WO2008024188
 US2008069820
 WO2008119567
 US2008254027
 WO2009080251
 WO2009080252
 WO2009080253
 WO2009080254
 WO2009089004
 US2009269787
 US2009304710
 US7695936
 US2010092482
 US2010196359
 US2010303828
 US2011171215
 US2011243929
 US2011250203
 US2011250213
 WO2012130831
 WO2013026833
 US2013216540
 US2013236476
 US2013251733
 US2013251711
 US8551478
 US2013273062
 WO2014164553
 US2014308276
 US2014377284
 US2015086574
 US2015232556
 US2015290316
 US2015344580
 US2016053014
 US2016145350
 EP3072522
 US2016304610
 US2016355587
 US2017198050
 WO2017134306
 US2017306016
 US2017313774
 US2018072804
 US2018104308
 WO2018148223
 US2018237529
 US2018256710
 WO2018223004
 US2018355043
 US2018362655
 US2019008955
 US2019048078
 US2019062448
 US2019071500
 US2019071503
 US2019079077
 US2019092868
 US10253095
 US2019119391
 US2019125832
 US2019169283
 US2019256598
 US2019276538
 US2019309069
 US2019322749
 US2019382488
 US2020023045
 US2020071404
 US2020071403
 US2020131272
 US2020148781
 US10668180
 US2020199228
 US2020216548
 US2020247898
 US2020277372
 US2020347144
 US2020399391
 US2020408765
 US2021009706
 US2021009687
    - HUSTON, Sci. U.S.A., (19880000), vol. 85, pages 5879 - 5883
    - JOHNSTON et al., Science, (19880000), vol. 242, pages 1038 - 1041
    - HOLLIGER, R et al., Proc. Natl. Acad. Sci. USA, (19930000), vol. 90, pages 64446448 - 6448
    - POLJAK, R. J, Structure, (19940000), vol. 2, pages 1121 - 1123
    - MILSTEINCUELLO, Nature, (19830000), vol. 305, page 537
    - TRAUNECKER et al., EMBO J., (19910000), vol. 10, page 3655
    - BRENNAN et al., Science, (19850000), vol. 229, page 81
    - KOSTELNY et al., J. Immunol., (19920000), vol. 148, no. 5, pages 1547 - 1553
    - GRUBER et al., J. Immunol., (19940000), vol. 152, page 5368
    - TUTT et al., J. Immunol., (19910000), vol. 147, page 60
    - BOSTROM et al., Science, (20090000), vol. 323, pages 1610 - 14
    - RIDGWAY et al., Prot Eng, (19960000), vol. 9, pages 617 - 621
    - CARTER, J Immunol Meth, (20010000), vol. 248, pages 7 - 15
    - CARTER, J Immunol Methods, (20010000), vol. 248, pages 7 - 15
    - HOUSTON, J. S., Methods in Enzymol., (19910000), vol. 203, pages 46 - 96
    - RAAGWHITLOW, FASEB, (19950000), vol. 9, pages 73 - 80
    - BIRDWALKER, TIBTECH, (19910000), vol. 9, pages 132 - 137
    - SOKOLOWSKA-WEDZINA et al., Mol. Cancer Res., (20170000), vol. 15, no. 8, pages 1040 - 1050
    - HASLER et al., Mol. Immunol., (20160000), vol. 75, pages 28 - 37
    - COSSINS et al., Prot Express Purif, (20060000), vol. 51, pages 253 - 259
    - LI et al., Immunol., (20170000), vol. 188, pages 89 - 95
    - MUYLDERMANS et al., TIBS, (20010000), vol. 26, pages 230 - 235
    - YAU et al., J Immunol Methods, (20030000), vol. 281, pages 161 - 75
    - MAASS et al., J Immunol Methods, (20070000), vol. 324, pages 13 - 25
    - BRINKMANNKONTERMANN, MAbs, (20170000), vol. 9, no. 2, pages 182 - 212
    - WANG et al., Antibodies, (20190000), vol. 8, page 28
    - DONG et al., MAbs, (20110000), vol. 3, pages 273 - 88
    - NATSUME et al., J. Biochem., (20060000), vol. 140, no. 3, pages 359 - 368
    - CHEAL et al., Mol. Cancer Ther., (20140000), vol. 13, no. 7, pages 1803 - 1812
    - WU et al., Nat Biotechnol, (20070000), vol. 25, pages 1290 - 97
    - CHELIUS et al., MAbs, (20100000), vol. 2, no. 3, pages 309 - 319
    - KONTERMANN et al., Drug Discovery Today, (20150000), vol. 20, no. 7, pages 838 - 847
    - GEBAUERSKERRA, "Engineered protein scaffolds as next-generation antibody therapeutics", Curr Opin Chem Biol, (20090000), vol. 13, pages 245 - 255
    - STUMPP et al., "Darpins: A new generation of protein therapeutics", Drug Discovery Today, (20080000), vol. 13, doi:10.1016/j.drudis.2008.04.013, pages 695 - 701, XP023440383

DOI:   http://dx.doi.org/10.1016/j.drudis.2008.04.013
    - Biochim Biophys Acta, (20000000), vol. 1482, pages 337 - 350
    - J. Mol. Biol., (20030000), vol. 332, pages 489 - 503
    - PNAS, (20030000), vol. 100, no. 4, pages 1700 - 1705
    - J. Mol. Biol., (20070000), vol. 369, pages 1015 - 1028
    - RAVETCHKINET, Annu. Rev. Immunol., (19910000), vol. 9, pages 457 - 492
    - HELLSTROM, I. et al., Proc. Nat'l Acad. Sci. USA, (19860000), vol. 83, pages 7059 - 7063
    - HELLSTROM, I et al., Proc. Nat'l Acad. Sci. USA, (19850000), vol. 82, pages 1499 - 1502
    - BRUGGEMANN, M. et al., J. Exp. Med., (19870000), vol. 166, pages 1351 - 1361
    - CLYNES et al., Proc. Nat'l Acad. Sci. USA, (19980000), vol. 95, pages 652 - 656
    - GAZZANO-SANTORO et al., J. Immunol. Methods, (19960000), vol. 202, page 163
    - CRAGG, M. S. et al., Blood, (20030000), vol. 101, pages 1045 - 1052
    - CRAGG, M. S.M. J. GLENNIE, Blood, (20040000), vol. 103, pages 2738 - 2743
    - SHIELDS et al., J. Biol. Chem., (20010000), vol. 9, no. 2, pages 6591 - 6604
    - IDUSOGIE et al., J. Immunol., (20000000), vol. 164, pages 4178 - 4184
    - A. L. LEHNINGER, Biochemistry, Worth Publishers, (19750000), pages 73 - 75
    - WALDER et al., Gene, (19860000), vol. 42, page 133
    - BAUER et al., Gene, (19850000), vol. 37, page 73
    - CRAIK, BioTechniques, (19850100), pages 12 - 19
    - LOHWASSER et al., International Immunology, (20010000), vol. 13, pages 321 - 327
    - SARANTOPOULOS et al., J. Clin. Invest., (20040000), vol. 114, no. 9, pages 1218 - 1221
    - GORMAN et al., PNAS, (19820000), vol. 79, page 6777
    - WEIDLE et al., Gene, (19870000), vol. 51, page 21
    - SABIN et al., Bio/Technol., (19890000), vol. 7, page 705
    - MILLER et al., Bio/Technol, (19890000), vol. 7, page 698
    - OKAYAMA et al., Mol. Cell. Biol., (19830000), vol. 3, page 280
    - GROSSCHEDL et al., Cell, (19850000), vol. 41, page 885
    - DNA Cloning, IRL Press, (19850000), vol. 45
    - SITARAMAN et al., Methods Mol. Biol., (20090000), vol. 498, pages 229 - 44
    - SPIRIN, Trends Biotechnol., (20040000), vol. 22, pages 538 - 45
    - ENDO et al., Biotechnol. Adv., (20030000), vol. 21, pages 695 - 713
    - HUSTON et al., Proc. Natl. Acad. Sci. USA, (19880000), vol. 85, pages 5879 - 5883
    - WARD et al., Nature, (19890000), vol. 334, pages 544 - 54
    - Immunol. Meth., Acad. Press, (19790000), vol. I & II
    - SALIGRAMA et al., Nature, (20190000), vol. 572, pages 481 - 487
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.