EP4168409 - VMAT2 INHIBITORS AND METHODS OF USE [Right-click to bookmark this link] | Status | Grant of patent is intended Status updated on 31.01.2024 Database last updated on 20.05.2024 | |
Former | Request for examination was made Status updated on 10.01.2024 | ||
Former | Grant of patent is intended Status updated on 12.06.2023 | ||
Former | Request for examination was made Status updated on 24.03.2023 | ||
Former | The international publication has been made Status updated on 30.09.2022 | ||
Former | unknown Status updated on 19.04.2022 | Most recent event Tooltip | 28.03.2024 | New entry: Renewal fee paid | Applicant(s) | For all designated states Neurocrine Biosciences, Inc. 12780 El Camino Real San Diego, California 92130 / US | [2023/17] | Inventor(s) | 01 /
HARRIOTT, Nicole San Diego, California 92130 / US | 02 /
PAGANO, Nicholas San Diego, California 92130 / US | 03 /
BOON, Byron A. San Diego, California 92130 / US | [2023/17] | Representative(s) | Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | [2023/17] | Application number, filing date | 22715479.6 | 21.03.2022 | [2023/17] | WO2022US21080 | Priority number, date | US202163164135P | 22.03.2021 Original published format: US 202163164135 P | [2023/17] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2022203984 | Date: | 29.09.2022 | Language: | EN | [2022/39] | Type: | A1 Application with search report | No.: | EP4168409 | Date: | 26.04.2023 | Language: | EN | The application published by WIPO in one of the EPO official languages on 29.09.2022 takes the place of the publication of the European patent application. | [2023/17] | Search report(s) | International search report - published on: | EP | 29.09.2022 | Classification | IPC: | C07D471/04, A61K31/4745, A61P25/00 | [2023/17] | CPC: |
C07D471/04 (EP,IL,KR,US);
A61K31/4745 (KR);
A61P25/00 (EP,IL,KR);
A61P25/18 (IL,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2023/17] | Extension states | BA | 19.01.2023 | ME | 19.01.2023 | Validation states | MA | 19.01.2023 | MD | 19.01.2023 | TN | 19.01.2023 | Title | German: | VMAT2-INHIBITOREN UND VERFAHREN ZUR VERWENDUNG | [2023/17] | English: | VMAT2 INHIBITORS AND METHODS OF USE | [2023/17] | French: | INHIBITEURS DE VMAT2 ET PROCÉDÉS D'UTILISATION | [2023/17] | Entry into regional phase | 19.01.2023 | National basic fee paid | 19.01.2023 | Designation fee(s) paid | 19.01.2023 | Examination fee paid | Examination procedure | 22.09.2022 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 19.01.2023 | Amendment by applicant (claims and/or description) | 19.01.2023 | Examination requested [2023/17] | 19.01.2023 | Date on which the examining division has become responsible | 13.06.2023 | Communication of intention to grant the patent | 14.11.2023 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time | 10.01.2024 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 01.02.2024 | Communication of intention to grant the patent | Request for further processing for: | The application is deemed to be withdrawn due to failure to fulfill actions required for granting the patent | 10.01.2024 | Request for further processing filed | 10.01.2024 | Full payment received (date of receipt of payment) Request granted | 17.01.2024 | Decision despatched | Fees paid | Renewal fee | 27.03.2024 | Renewal fee patent year 03 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [Y]WO2009070552 (GEN ELECTRIC [US], et al) [Y] 1-138 * claim 2 *; | [Y]WO2021027792 (SHANDONG LUYE PHARMACEUTICAL CO LTD [CN]) [Y] 1-138 * claim 1 *; | [A] - DIMITRI E. GRIGORIADIS ET AL, "Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, US, (20170412), vol. 361, no. 3, doi:10.1124/jpet.116.239160, ISSN 0022-3565, pages 454 - 461, XP055486504 [A] 1-138 * figure 1 * DOI: http://dx.doi.org/10.1124/jpet.116.239160 | [A] - ZHANGYU YAO ET AL, "Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 46, no. 5, doi:10.1016/J.EJMECH.2011.02.046, ISSN 0223-5234, (20110217), pages 1841 - 1848, (20110223), XP028370954 [A] 1-138 * the whole document * DOI: http://dx.doi.org/10.1016/j.ejmech.2011.02.046 | by applicant | WO2008058261 | WO2018195121 | - SCHERMAN et al., Proc. Natl. Acad. Sci. USA, (19830000), vol. 80, pages 584 - 8 | - PETTIBONE et al., Eur. J. Pharmacol., (19840000), vol. 102, pages 431 - 6 | - LOGIN et al., Ann. Neurology, (19820000), vol. 12, pages 257 - 62 | - RECHES et al., J. Pharmacol. Exp. Ther., (19830000), vol. 225, pages 515 - 521 | - ZHU, G-D, J. Org. Chem., (20020000), vol. 67, pages 943 - 948 | - ORTHO, "Iodination of phenols: This procedure allows for the incorporation of I at the ortho position of a phenol as reported by Collier, T. L. and co-workers in J. Labelled Compd", Radiopharm, (19990000), vol. 42, pages S264 - S266 | - BAS, M.-D, "J. Labelled Compd", Radiopharm, (20010000), vol. 44, pages S280 - S282 | - NEAR, Mol. Pharmacol., (19860000), vol. 30, pages 252 - 57 | - TENG et al., J. Neurochem., (19980000), vol. 71, pages 258 - 65 | - HOARE et al., Peptides, (20030000), vol. 24, pages 1881 - 97 | - WADENBERGHICKS, Neuroscience and Biobehavioral Reviews, (19990000), vol. 23, pages 851 - 862 |