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Extract from the Register of European Patents

EP About this file: EP4355747

EP4355747 - (R)-N-ETHYL-5-FLUORO-N-ISOPROPYL-2-((5-(2-(6-((2-METHOXYETHYL)(METHYL)AMINO)-2-METHYLHEXAN-3-YL)-2,6-DIAZASPIRO[3.4]OCTAN-6-YL)-1,2,4-TRIAZIN-6-YL)OXY)BENZAMIDE BESYLATE SALT FOR THE TREATMENT OF DISEASES SUCH AS CANCER [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  22.03.2024
Database last updated on 05.10.2024
FormerThe international publication has been made
Status updated on  23.12.2022
Formerunknown
Status updated on  04.07.2022
Most recent event   Tooltip30.07.2024Amendment by applicant 
Applicant(s)For all designated states
JANSSEN Pharmaceutica NV
Turnhoutseweg 30
2340 Beerse / BE
[2024/17]
Inventor(s)01 / CAI, Wei
Shanghai 200233 / CN
02 / DAI, Xuedong
Shanghai 200233 / CN
03 / QUEROLLE, Olivier Alexis Georges
92787 Issy-les Moulineaux Cedex 9 / FR
04 / THURING, Johannes Wilhelmus J.
2340 Beerse / BE
05 / NG, Alicia Tee Fuay
Shanghai 200233 / CN
06 / DARVILLE, Nicolas Freddy Jacques Bruno
2340 Beerse / BE
07 / GEERTMAN, Robert Michael
2340 Beerse / BE
08 / AHUJA, Dipali
2340 Beerse / BE
09 / LIU, Yingtao
Shanghai 200233 / CN
10 / PANDE, Vineet
2340 Beerse / BE
11 / CLEATOR, Edward
High Wycombe, HP12 4EG / GB
12 / BEN HAIM, Cyril
2340 Beerse / BE
13 / SMOLDERS, Simon Jan C
2340 Beerse / BE
 [2024/17]
Representative(s)Lenaerts, Philip
Johnson & Johnson Patent Law Department
Turnhoutseweg 30
2340 Beerse / BE
[2024/17]
Application number, filing date22733288.916.06.2022
[2024/17]
WO2022CN99089
Priority number, dateWO2021CN10046617.06.2021         Original published format: PCT/CN2021/100466
WO2022CN9167709.05.2022         Original published format: PCT/CN2022/091677
[2024/17]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022262796
Date:22.12.2022
Language:EN
[2022/51]
Type: A1 Application with search report 
No.:EP4355747
Date:24.04.2024
Language:EN
The application published by WIPO in one of the EPO official languages on 22.12.2022 takes the place of the publication of the European patent application.
[2024/17]
Search report(s)International search report - published on:EP22.12.2022
ClassificationIPC:C07D487/04, A61P35/00, A61K31/53, C07C1/00, C07D487/10
[2024/17]
CPC:
C07D487/10 (EP,IL,KR); A61K31/53 (KR); A61P35/00 (EP,IL,KR);
A61P35/02 (KR); C07C231/02 (EP,IL,KR); C07C235/46 (KR);
C07C235/60 (IL); C07B2200/13 (KR) (-)
C-Set:
C07C231/02, C07C235/60 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2024/17]
Extension statesBA17.01.2024
ME17.01.2024
Validation statesKH17.01.2024
MA17.01.2024
MD17.01.2024
TN17.01.2024
TitleGerman:(R)-N-ETHYL-5-FLUOR-N-ISOPROPYL-2-(5-(2-((2-METHOXYETHYL)(METHYL)AMINO)-2-METHYLHEXAN-3-YL)-2,6-DIAZASPIRO[3.4 OCTAN-6-YL)1,2,4-TRIAZIN-6-YL)OXY)BENZAMID-BESYLATSALZ[2024/17]
English:(R)-N-ETHYL-5-FLUORO-N-ISOPROPYL-2-((5-(2-(6-((2-METHOXYETHYL)(METHYL)AMINO)-2-METHYLHEXAN-3-YL)-2,6-DIAZASPIRO[3.4]OCTAN-6-YL)-1,2,4-TRIAZIN-6-YL)OXY)BENZAMIDE BESYLATE SALT FOR THE TREATMENT OF DISEASES SUCH AS CANCER[2024/17]
French:SEL DE BÉSYLATE (R)-N-ÉTHYL-5-FLUORO-N-ISOPROPYL-2-((5-(2-(6-((2-MÉTHOXYÉTHYL)(MÉTHYL)AMINO)-2-M ÉTHYLHEXAN-3-YL)-2,6-DIAZASPIRO[3.4]OCTAN-6-YL)-1,2,4-TRIAZIN-6-YL)OXY)BENZAMIDE POUR LE TRAITEMENT DE MALADIES TELLES QUE LE CANCER[2024/17]
Entry into regional phase17.01.2024National basic fee paid 
17.01.2024Designation fee(s) paid 
17.01.2024Examination fee paid 
Examination procedure17.01.2024Examination requested  [2024/17]
17.01.2024Date on which the examining division has become responsible
29.07.2024Amendment by applicant (claims and/or description)
Fees paidRenewal fee
01.07.2024Renewal fee patent year 03
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[AD]EP3394064  (VITAE PHARMACEUTICALS INC [US]);
 [IDA]EP3468966  (VITAE PHARMACEUTICALS INC [US]);
 [XP]WO2021121327  (JANSSEN PHARMACEUTICA NV [BE], et al)
by applicantWO2011029054
 WO2014164543
 WO2016040330
 WO2016195776
 WO2016197027
 WO2017112768
 WO2017132398
 WO2017161002
 WO2017161028
 WO2017192543
 WO2017207387
 WO2017214367
 WO2018024602
 WO2018053267
 WO2018050686
 WO2018050684
 WO2018106818
 WO2018106820
 WO2018109088
 WO2018153312
 WO2018175746
 WO2018226976
 WO2019060365
 WO2020069027
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.