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EP4276172
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| EP4276172 - MEDIUM FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, METHOD FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, AND METHOD FOR PRODUCING RENAL ORGANOIDS [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 13.10.2023 Database last updated on 09.09.2024 | |
| Former | The international publication has been made Status updated on 15.07.2022 | Most recent event Tooltip | 15.03.2024 | Change: Validation states | published on 17.04.2024 [2024/16] | 15.03.2024 | Change - extension states | published on 17.04.2024 [2024/16] | Applicant(s) | For all designated states Kyoto University 36-1, Yoshida-honmachi Sakyo-ku Kyoto-shi, Kyoto 606-8501 / JP | For all designated states Rege Nephro Co., Ltd. Med-Pharm Collaboration bldg, Kyoto University 46-29, Yoshidashimoadachi-cho, Sakyo-ku Kyoto-shi, Kyoto, 606-8501 / JP | [2023/46] | Inventor(s) | 01 /
OSAFUNE, Kenji Kyoto-shi, Kyoto 606-8501 / JP | 02 /
ARAOKA, Toshikazu Kyoto-shi, Kyoto 606-8501 / JP | 03 /
KOBAYASHI, Yoshifumi Kyoto-shi, Kyoto 606-8501 / JP | 04 /
RYOSAKA, Makoto Kyoto-shi, Kyoto 606-8501 / JP | 05 /
TSUJIMOTO, Hiraku Kyoto-shi, Kyoto 606-8501 / JP | [2023/46] | Representative(s) | Cabinet Becker et Associés 25, rue Louis le Grand 75002 Paris / FR | [2023/46] | Application number, filing date | 22736784.4 | 11.01.2022 | [2023/46] | WO2022JP00564 | Priority number, date | JP20210002203 | 08.01.2021 Original published format: JP 2021002203 | [2023/46] | Filing language | JA | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2022149616 | Date: | 14.07.2022 | Language: | JA | [2022/28] | Type: | A1 Application with search report | No.: | EP4276172 | Date: | 15.11.2023 | Language: | EN | [2023/46] | Search report(s) | International search report - published on: | JP | 14.07.2022 | Classification | IPC: | C12N5/077, C12N5/10 | [2023/46] | CPC: |
C12N5/0686 (EP);
C12N5/0687 (US);
C12N2501/115 (EP,US);
C12N2501/119 (US);
C12N2501/15 (EP,US);
C12N2501/155 (EP,US);
C12N2501/385 (EP);
C12N2501/727 (EP);
C12N2506/45 (EP,US);
C12N2513/00 (EP)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2023/46] | Title | German: | MEDIUM ZUR KULTIVIERUNG UND EXPANSION VON NEPHRONVORLÄUFERZELLEN, VERFAHREN ZUR KULTIVIERUNG UND EXPANSION VON NEPHRONVORLÄUFERZELLEN UND VERFAHREN ZUR HERSTELLUNG VON NIERENORGANOIDEN | [2023/46] | English: | MEDIUM FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, METHOD FOR CULTURING AND EXPANDING NEPHRON PROGENITOR CELLS, AND METHOD FOR PRODUCING RENAL ORGANOIDS | [2023/46] | French: | MILIEU DE CULTURE ET DE MULTIPLICATION DE CELLULES PROGÉNITRICES DE NÉPHRON, PROCÉDÉ DE CULTURE ET DE MULTIPLICATION DE CELLULES PROGÉNITRICES NÉPHRONIQUES, ET PROCÉDÉ DE PRODUCTION D'ORGANOÏDES RÉNAUX | [2023/46] | Entry into regional phase | 13.07.2023 | Translation filed | 13.07.2023 | National basic fee paid | 13.07.2023 | Search fee paid | 13.07.2023 | Designation fee(s) paid | 13.07.2023 | Examination fee paid | Examination procedure | 13.07.2023 | Amendment by applicant (claims and/or description) | 13.07.2023 | Examination requested [2023/46] | Fees paid | Renewal fee | 22.01.2024 | Renewal fee patent year 03 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [YX]US2015275168 (OXBURGH LEIF [US], et al) [Y] 2-4 * claims, paragraphs [0012], [0048], [0059] * [X] 1, 5, 6, 8-12, 16-18, 22; | [YX]WO2017010448 (NAT UNIV CORP KUMAMOTO UNIV [JP]) [Y] 2-4 * claims, paragraphs [0035], [0042] * [X] 1, 5, 6, 8-12, 16-18, 22; | [YX]US2017205396 (IZPISUA BELMONTE JUAN CARLOS [US], et al) [Y] 2-4 * claims, paragraph [0048] * [X] 1, 5, 6, 8-12, 16-18, 22; | [A]WO2018216743 (UNIV KYOTO [JP]) [A] 1-22* entire text *; | [A]WO2020213734 (UNIV KYOTO [JP]) [A] 1-22 * entire text *; | [PX]WO2021125340 (UNIV KYOTO [JP]) [PX] 1-6, 8-12, 16-18, 22 * claims, paragraphs [0008], [0014], [0053], [0055], examples *; | [YX] - Tsujimoto Hiraku; Araoka Toshikazu; Nishi Yohei; Ohta Akira; Nakahata Tatsutoshi; Osafune Kenji, "Small molecule TCS21311 can replace BMP7 and facilitate cell proliferation in in vitro expansion culture of nephron progenitor cells", Biochemical and Biophysical Research Communications, Elsevier, Amsterdam NL, Amsterdam NL , (20200226), vol. 558, doi:10.1016/j.bbrc.2020.02.130, ISSN 0006-291X, pages 231 - 238, XP086572913 [Y] 2-4 * p. 232, left column, fig. 1B, 1C * [X] 1-6, 8-12, 16-18, 22 DOI: http://dx.doi.org/10.1016/j.bbrc.2020.02.130 | by applicant | US2003087919 | US2003125344 | WO03059913 | WO03062227 | WO03062225 | US2004002508 | US2004002507 | US2004014755 | WO2004039796 | US2005192304 | US2005209261 | WO2009146408 | WO2011043405 | WO2014200115 | WO2017043666 | WO2018216743 | WO2020022261 | JP2021002203 | WO2022076976 | - OSAFUNE K. et al., "Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay", Development, (20060000), vol. 133, doi:10.1242/dev.02174, pages 151 - 61, XP002581530 DOI: http://dx.doi.org/10.1242/dev.02174 | - KOBAYASHI A. et al., "Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development", Cell Stem Cell, (20080000), vol. 3, doi:10.1016/j.stem.2008.05.020, pages 169 - 81, XP055078817 DOI: http://dx.doi.org/10.1016/j.stem.2008.05.020 | - "Gene Editing in 3D Cultured Nephron Progenitor Cell Lines", Z. LIT. ARAOKAJ.C.I. BELMONTE, Kidney Organog Methods Protoc, Hummana Press, (20190000), pages 151 - 159 | - OSAFUNE K et al., Development, (20060000), vol. 133, pages 151 - 61 | - Cell Stem Cell, (20080000), vol. 3, pages 169 - 181 | - Nat Commun, vol. 4, page 1367 | - "NCBI", Database accession no. NP_062825.1 | - ISHIZAKI et al., Mol. Pharmacol., (20000000), vol. 57, pages 976 - 983 | - NARUMIYA et al., Methods Enzymol., (20000000), vol. 325, pages 273 - 284 | - UENATA et al., Nature, (19970000), vol. 389, pages 990 - 994 | - SASAKI et al., Pharmacol. Ther., (20020000), vol. 93, pages 225 - 232 | - NAKAJIMA et al., Cancer Chemother Pharmacol., (20030000), vol. 52, no. 4, pages 319 - 324 | - BARAK, H. et al., "FGF9 and FGF20 Maintain the Sternness of Nephron Progenitors in Mice and Man", Dev. Cell, (20120000), vol. 22, doi:10.1016/j.devcel.2012.04.018, pages 1191 - 1207, XP028490953 DOI: http://dx.doi.org/10.1016/j.devcel.2012.04.018 | - CAS , no. 1187594-09-7 | - Cas , no. 58753-54-1 | - TAMURA K et al., Cell Differ. Dev., (19900000), vol. 32, pages 17 - 26 | - STRICKLAND S et al., Cancer Res., (19830000), vol. 43, pages 5268 - 5272 | - TANENAGA, K. et al., Cancer Res., (19800000), vol. 40, pages 914 - 919 | - LINDEMANN et al., Mol. Cancer, (20030000), vol. 2, page 20 | - P. B. YU et al., Circulation, (20070000), vol. 116, page 60 | - P. B. YU et al., Nat. Chem. Biol., (20080000), vol. 4, pages 33 - 41 | - J. HAO et al., PLoS ONE, (20080000), vol. 3, no. 8, page e2904 | - Nat Biotechnol, (20100000), vol. 28, pages 611 - 615 | - EMBO J., (19840000), vol. 3, pages 1463 - 1468 | - J. Cell Biol., (19870000), vol. 105, pages 589 - 598 | - Nature, (20150000), vol. 526, pages 564 - 568 | - Dev Cell, (20120911), vol. 23, no. 3, pages 637 - 651 | - C.A. SCHNEIDER et al., Nat Methods., (20120000), vol. 9, pages 671 - 675 |