Extract from the Register of European Patents

EP About this file: EP4289938

EP4289938 - CELL-DERIVED VESICLES WITH INCREASED CELLULAR UPTAKE CAPACITY AND METHOD FOR PRODUCING SAME [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  14.11.2025
Database last updated on 24.03.2026
FormerRequest for examination was made
Status updated on  10.11.2023
FormerThe international publication has been made
Status updated on  12.08.2022
Most recent event   Tooltip14.11.2025Application deemed to be withdrawnpublished on 17.12.2025  [2025/51]
Applicant(s)For all designated states
MDimune Inc.
1001, 49 Achasan-ro
Seongdong-gu
Seoul 04790 / KR
[2023/50]
Inventor(s)01 / BAE, Shin Gyu
Seoul 04790 / KR
02 / OH, Seung Wook
Seoul 04790 / KR
03 / PARK, Jung Eun
Seoul 04790 / KR
04 / PARK, Sung Soo
Seoul 04790 / KR
05 / KWON, Ye Rim
Seoul 04790 / KR
06 / LAU, Hui Chong
Seoul 04791 / KR
07 / PARK, Jin Hee
Seoul 04790 / KR
 [2023/50]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[2023/50]
Application number, filing date22750007.128.01.2022
[2023/50]
WO2022KR01673
Priority number, dateKR2021001450002.02.2021         Original published format: KR 20210014500
[2023/50]
Filing languageKO
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2022169258
Date:11.08.2022
Language:KO
[2022/32]
Type: A1 Application with search report 
No.:EP4289938
Date:13.12.2023
Language:EN
[2023/50]
Search report(s)International search report - published on:KR11.08.2022
(Supplementary) European search report - dispatched on:EP13.01.2025
ClassificationIPC:C12N5/0775, C07K14/705, A61K47/69, C12N5/071
[2025/07]
CPC:
C12N5/0668 (EP); C12N5/0605 (KR); A61K47/6901 (US);
A61K35/22 (US); A61K35/28 (US); A61K9/127 (EP,KR);
A61K9/5068 (EP); C07K14/705 (EP); C07K14/70596 (EP);
C12N5/0662 (KR); C12N5/0684 (EP); C12N5/0687 (EP);
C12N2502/137 (EP); C12N2502/256 (EP); C12N2527/00 (KR) (-)
Former IPC [2023/50]C12N5/0775, C07K14/705, A61K47/69
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2023/50]
TitleGerman:AUS ZELLEN ABGELEITETE VESIKEL MIT ERHÖHTER ZELLAUFNAHMEKAPAZITÄT UND VERFAHREN ZUR HERSTELLUNG DAVON[2023/50]
English:CELL-DERIVED VESICLES WITH INCREASED CELLULAR UPTAKE CAPACITY AND METHOD FOR PRODUCING SAME[2023/50]
French:VÉSICULES DÉRIVÉES DE CELLULES AYANT UNE CAPACITÉ D'ABSORPTION CELLULAIRE ACCRUE ET PROCÉDÉ POUR LES PRODUIRE[2023/50]
Entry into regional phase24.08.2023Translation filed 
24.08.2023National basic fee paid 
24.08.2023Search fee paid 
24.08.2023Designation fee(s) paid 
24.08.2023Examination fee paid 
Examination procedure24.08.2023Examination requested  [2023/50]
31.07.2025Application deemed to be withdrawn, date of legal effect  [2025/51]
14.08.2025Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2025/51]
Fees paidRenewal fee
17.01.2024Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.01.202504   M06   Not yet paid
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Documents cited:Search[X] US2019167587  (BAE SHIN GYU et al.)
 [X] CN109913407  (UNIV ZHEJIANG et al.) [X] 1-15 * example 1 *
 [X]   NASIRI KENARI AMIRMOHAMMAD ET AL: "Methods for loading therapeutics into extracellular vesicles and generating extracellular vesicles mimetic-nanovesicles", METHODS, ACADEMIC PRESS, NL, vol. 177, 7 January 2020 (2020-01-07), pages 103 - 113, XP086150058, ISSN: 1046-2023, [retrieved on 20200107], DOI: 10.1016/J.YMETH.2020.01.001

DOI:   http://dx.doi.org/10.1016/j.ymeth.2020.01.001
 [X]   WANG LIXUE ET AL: "Preparation of Engineered Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells with Ultrasonication for Skin Rejuvenation", ACS OMEGA, vol. 4, no. 27, 19 December 2019 (2019-12-19), US, pages 22638 - 22645, XP055846123, ISSN: 2470-1343, Retrieved from the Internet DOI: 10.1021/acsomega.9b03561

DOI:   http://dx.doi.org/10.1021/acsomega.9b03561
International search[XY] KR20110002443  (AEON MEDIX INC et al.) [X] 1,3-7,12-13 * See abstract; claims 1-11 and 27-33; and paragraphs [0110] and [0143]-[0147]. *[Y] 2,8-11
 [XY] KR20180003322  (AMOREPACIFIC CORP et al.) [X] 1,3-7,12-13 * See claims 1-14. *[Y] 2,8-11
 [XY] KR20140118524  (POSTECH ACAD IND FOUND et al.) [X] 1,3-7,12-13 * See claims 1-5 and 10; and paragraphs [0006] and [0040]-[0041]. *[Y] 2,8-11
 [Y]   BURBIDGE KEVIN, ET AL: "Cargo and cellspecific differences in extracellular vesicle populations identified by multiplexed immunofluorescent analysis", JOURNAL OF EXTRACELLULAR VESICLES, TAYLOR & FRANCIS, UK, vol. 9, no. 1, 1 September 2020 (2020-09-01), UK , pages 1789326, XP055955660, ISSN: 2001-3078, DOI: 10.1080/20013078.2020.1789326 [Y] 2,8-11 * See page 10; and figure 1. *

DOI:   http://dx.doi.org/10.1080/20013078.2020.1789326
 [PX]   HAN, DONG WOO; PARK, JINHEE; LEE, JINJU; YOON, JUN-SIK; KIM, DAYEON; LAU, HUI-CHONG; YOON, JEONG SEON; OH, SEUNG WOOK: "PS02.10 BioDrone, a novel drug delivery platform: From the basic science to potential therapeutic promises", JOURNAL OF EXTRACELLULAR VESICLES, TAYLOR & FRANCIS, UK, vol. 10, no. S1, 15 May 2021 (2021-05-15), UK , pages 126 - 127, XP009538683, ISSN: 2001-3078 [PX] 1-13 * See entire document. * * This document is a known document declaring exceptions to lack of novelty by the applicant. *
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