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Extract from the Register of European Patents

EP About this file: EP4341406

EP4341406 - COMPOUNDS FOR MODULATING UNC13A EXPRESSION [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  23.02.2024
Database last updated on 15.07.2024
FormerThe international publication has been made
Status updated on  26.11.2022
Most recent event   Tooltip12.07.2024Amendment by applicant 
Applicant(s)For all designated states
Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
[2024/13]
Inventor(s)01 / VALAS, Ruben, E.
Oceanside, CA 92056 / US
02 / LING, Kar, Yun Karen
Carlsbad, CA 92010 / US
 [2024/13]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2024/13]
Application number, filing date22805616.420.05.2022
[2024/13]
WO2022US30335
Priority number, dateUS202163191905P21.05.2021         Original published format: US 202163191905 P
[2024/13]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2022246251
Date:24.11.2022
Language:EN
[2022/47]
Type: A2 Application without search report 
No.:EP4341406
Date:27.03.2024
Language:EN
The application published by WIPO in one of the EPO official languages on 24.11.2022 takes the place of the publication of the European patent application.
[2024/13]
Search report(s)International search report - published on:US29.12.2022
ClassificationIPC:C12N15/113, A61K31/712, A61K31/7125, A61P25/28
[2024/13]
CPC:
C12N15/113 (EP); C12N2310/11 (EP); C12N2310/315 (EP);
C12N2310/322 (EP); C12N2310/3341 (EP)
C-Set:
C12N2310/322, C12N2310/3525 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2024/13]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:VERBINDUNGEN ZUR MODULATION DER UNC13A-EXPRESSION[2024/13]
English:COMPOUNDS FOR MODULATING UNC13A EXPRESSION[2024/13]
French:COMPOSÉS POUR MODULER L'EXPRESSION D'UNC13A[2024/13]
Entry into regional phase15.12.2023National basic fee paid 
15.12.2023Search fee paid 
15.12.2023Designation fee(s) paid 
15.12.2023Examination fee paid 
Examination procedure15.12.2023Examination requested  [2024/13]
10.07.2024Amendment by applicant (claims and/or description)
Fees paidRenewal fee
13.03.2024Renewal fee patent year 03
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Cited inInternational search[YA]US2011195848  (ROOPRA AVTAR S [US], et al) [Y] 3, 5, 6, 8/(5,6), 10 * . Especially SEQ ID NO: 221 *[A] 7, 8/7;
 [YA]WO2019051173  (IONIS PHARMACEUTICALS INC [US]) [Y] 1-3, 5, 6, 8/(5,6), 10 * . Especially claims 1, 11 * [A] 7, 8/7;
 [Y]  - Deng Lunbin, Kaeser Pascal S., Xu Wei, Südhof Thomas C., "RIM Proteins Activate Vesicle Priming by Reversing Auto-Inhibitory Homodimerization of Munc13", Neuron, ELSEVIER, AMSTERDAM, NL, AMSTERDAM, NL, (20110127), vol. 69, no. 2, doi:10.1016/j.neuron.2011.01.005, ISSN 0896-6273, pages 317 - 331, XP093020823 [Y] 1-3 * . Especially pg 325 col 2 para 2, pg 329 col 2 para 3. *

DOI:   http://dx.doi.org/10.1016/j.neuron.2011.01.005
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.