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Extract from the Register of European Patents

EP About this file: EP0030815

EP0030815 - Hybrid cell line for producing monoclonal antibody to a human prothymocyte antigen, antibody, method of preparation of this antibody, diagnostic and therapeutic uses, and pharmaceutical compositions comprising this antibody [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  23.10.1998
Database last updated on 03.04.2025
Most recent event   Tooltip17.04.2015Change - lapse in a contracting state
State(s) deleted from list of lapses: CH, LI
published on 20.05.2015  [2015/21]
Applicant(s)For all designated states
ORTHO PHARMACEUTICAL CORPORATION
U.S. Route 202 P.O. Box 300 Raritan
New Jersey 08869-0602 / US
[N/P]
Former [1981/25]For all designated states
ORTHO PHARMACEUTICAL CORPORATION
U.S. Route 202 P.O. Box 300
Raritan New Jersey 08869-0602 / US
Inventor(s)01 / Kung, Patrick Chung-Shu
1096 Rector Road
Bridgewater New Jersey / US
02 / Goldstein, Gideon
30 Dorison Drive
Short Hills New Jersey / US
[1981/25]
Representative(s)Jones, Alan John, et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London, WC1A 2RA / GB
[N/P]
Former [1981/25]Jones, Alan John, et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London, WC1A 2RA / GB
Application number, filing date80304350.403.12.1980
[1981/25]
Priority number, dateUS1979010007204.12.1979         Original published format: US 100072
[1981/25]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0030815
Date:24.06.1981
Language:EN
[1981/25]
Type: A3 Search report 
No.:EP0030815
Date:30.12.1981
Language:EN
[1981/52]
Type: B1 Patent specification 
No.:EP0030815
Date:15.05.1985
Language:EN
[1985/20]
Search report(s)(Supplementary) European search report - dispatched on:EP26.10.1981
ClassificationIPC:C12P1/00, C12N5/00, C12N15/00, G01N33/50, A61K39/395, // C12R1/91
[1985/20]
CPC:
C07K16/2896 (EP,US); A61P37/00 (EP); A61K38/00 (EP,US);
Y10S530/808 (EP,US)
Former IPC [1981/25]C12P1/00, C12N5/00, C12N15/00, G01N33/54, A61K39/395, // C12R1/91
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   NL,   SE [1981/25]
TitleGerman:Hybridzellinie zur Herstellung monoklonaler Antikörper gegen ein menschliches Prothymozyt-Antigen; Antikörper und Verfahren zu seiner Herstellung; diagnostische und therapeutische Verwendungen und diesen Antikörper enthaltende pharmazeutische Zusammensetzungen[1981/25]
English:Hybrid cell line for producing monoclonal antibody to a human prothymocyte antigen, antibody, method of preparation of this antibody, diagnostic and therapeutic uses, and pharmaceutical compositions comprising this antibody[1981/25]
French:Lignée de cellules hybrides pour la préparation d'anticorps monoclonaux contre un antigène prothymocyte humain; anticorps; procédé pour préparer cet anticorps, applications diagnostiques et thérapeutiques et compositions pharmaceutiques contenant cet anticorps[1981/25]
Biological materialThis application mentions deposited biological material, check the file for details
Examination procedure03.06.1982Examination requested  [1982/33]
26.09.1983Despatch of a communication from the examining division (Time limit: M04)
07.11.1983Reply to a communication from the examining division
25.05.1984Despatch of communication of intention to grant (Approval: )
31.07.1984Communication of intention to grant the patent
19.09.1984Fee for grant paid
19.09.1984Fee for publishing/printing paid
Opposition(s)Opponent(s)01  11.02.1986  23.04.1986  ADMISSIBLE
Behringwerke Aktiengesellschaft
Postfach 11 40
D-35001 Marburg / DE
 02  11.02.1986  23.04.1986  ADMISSIBLE
Dolder, Fritz
Rosenbergstrasse 6 Postfach 558
CH-8304 Wallisellen / CH
 03  13.02.1986  23.04.1986  ADMISSIBLE
Becton, Dickinson and Company
Mack Centre Drive
Paramus, New Jersey 07652 / US
Opponent's representative
Ruffles, Graham Keith
Marks & Clerk LLP 62-68 Hills Road Cambridge
CB2 1LA / GB
 04  14.02.1986  23.04.1986  ADMISSIBLE
Boehringer Mannheim GmbH Patentabteilung
Sandhofer Strasse 116
D-68298 Mannheim / DE
Opponent's representative
Fincke, Karl Theodor
Patentanwälte H. Weickmann, Dr. K. Fincke F.A. Weickmann, B. Huber Dr. H. Liska, Dr. J. Prechtel, Dr. B. Böhm Postfach 86 08 20
D-81635 München / DE
 [N/P]
Former [1986/15]
Opponent(s)01  11.02.1986  23.04.1986  ADMISSIBLE
Behringwerke Aktiengesellschaft
Postfach 11 40
D-35001 Marburg / DE
 02  11.02.1986  23.04.1986  ADMISSIBLE
Dolder, Fritz
Rosenbergstrasse 6 Postfach 558
CH-8304 Wallisellen / CH
 03  13.02.1986  23.04.1986  ADMISSIBLE
Becton, Dickinson and Company
Mack Centre Drive
Paramus, New Jersey 07652 / US
Opponent's representative
Ruffles, Graham Keith
MARKS & CLERK, 57-60 Lincoln's Inn Fields
London WC2A 3LS / GB
 04  14.02.1986  23.04.1986  ADMISSIBLE
Boehringer Mannheim GmbH Patentabteilung
Sandhofer Strasse 116
D-68298 Mannheim / DE
Opponent's representative
Fincke, Karl Theodor, Dipl.-Phys. Dr.
Patentanwälte H. Weickmann, Dr. K. Fincke F.A. Weickmann, B. Huber Dr. H. Liska, Dr. J. Prechtel, Dr. B. Böhm Postfach 86 08 20
D-81635 München / DE
24.04.1986Invitation to proprietor to file observations on the notice of opposition
01.10.1987Reply of patent proprietor to notice(s) of opposition
04.07.1988Despatch of a communication from the opposition division (Time limit: M06)
13.01.1989Reply to a communication from the opposition division
20.08.1991Despatch of a communication from the opposition division (Time limit: M11)
23.07.1992Reply to a communication from the opposition division
06.05.1993Despatch of a communication from the opposition division (Time limit: M04)
16.09.1993Reply to a communication from the opposition division
09.03.1994Date of oral proceedings
22.04.1994Despatch of minutes of oral proceedings
23.06.1998Legal effect of revocation of patent [1998/50]
23.06.1998Despatch of communication that the patent will be revoked
Appeal following opposition31.05.1994Appeal received No.  T0512/94
18.08.1994Statement of grounds filed
23.06.1998Result of appeal procedure: revocation of the patent
23.06.1998Date of oral proceedings
11.03.1998Minutes of the oral proceedings despatched
Fees paidRenewal fee
18.12.1982Renewal fee patent year 03
10.12.1983Renewal fee patent year 04
13.12.1984Renewal fee patent year 05
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Lapses during opposition  Tooltipdeleted
[2015/21]
Former [2000/52]CH15.05.1985
LI15.05.1985
Documents cited:Search   [ ] - BIOLOGICAL ABSTRACTS, vol. 69, no. 10, 1980, Philadelphia, USA, P. LAKE et al."Production and characterization of cytotoxic Thy-1 antibody secreting hybrid cell lines: detection of thymus derived cell subsets", page 6917, abstract 64810 & EUR. J. IMMUNOL. 9 (11), 875-86, 1979
    [ ] - BIOLOGICAL ABSTRACTS, vol. 68, no. 5, 1979, Philadelphia, USA, R. DULBECCO et al " Role of Thy-1 antigen in the in vitro differentiation of a rat mammary cell line", page 2853, abstract 28600 & PROC. NATL. ACAD. SCI, USA 76(4), 1848-52, 1979
 [D]  - SCIENCE, vol. 206, October 19, 1979, P.C. KUNG et al. "Monoclonal antibodies defining distinctive human T cell surface antigens", pages 347-349
 [AD]  - NATURE, vol. 256, August 7, 1975, G. KOHLER et al. "Continuous cultures of fused cells secreting antibody of predefined specificity", pages 495-497.
 [AD]  - CHEMICAL & ENGINEERING NEWS, vol. 57, no. 1, January 1, 1979, J.L. FOX "Antibody reagents revolutionizing immunology", pages 15-17.
 [XP]  - TRANSPLANTATION PROCEEDINGS, vol. 12, no. 3, Suppl. 1, September 1980, P.C. KUNG et al. "Strategies for generating monoclonal antibodies defining human T-lymphocyte differentiation antigens", pages 141-146.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.