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EP About this file: EP0133403

EP0133403 - Necleotide sequence coding for the signal peptide of diphteria toxine, vector containing this nucleotide sequence, its use in the transformation of microorganisms and peptide compositions obtained [Right-click to bookmark this link]
Status	The application has been refused Status updated on 02.08.1993 Database last updated on 07.10.2024
Most recent event Tooltip	07.07.2007	Change - inventor	published on 08.08.2007 [2007/32]
Applicant(s)	For all designated states INSTITUT PASTEUR 25-28, rue du Docteur Roux 75724 Paris Cedex 15 / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac 75654 Paris Cédex 13 / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac 75654 Paris Cédex 13 / FR
	[N/P]
Former [1990/07]	For all designated states INSTITUT PASTEUR 25-28, rue du Docteur Roux F-75724 Paris Cédex 15 / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac F-75654 Paris Cédex 13 / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac F-75654 Paris Cédex 13 / FR
Former [1985/08]	For all designated states GROUPEMENT DE GENIE GENETIQUE (G3) 28, rue du Docteur Roux F-75015 Paris / FR
	For all designated states INSTITUT PASTEUR 25-28, rue du Docteur Roux F-75724 Paris Cédex 15 / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac F-75654 Paris Cédex 13 / FR
Inventor(s)	01 / Kaczorek, Michel 6, rue Mayran F-75009 Paris / FR
	02 / Tiollais, Pierre 16, rue de la Glacière F-75013 Paris / FR
	03 / Chenciner, Nicole 11, Quai Bourbon F-75004 Paris / FR
	04 / Streeck, Rolf E. 17 bis, avenue Foch F-75116 Paris / FR
	05 / Boquet, Patrice 1, rue du Puits Georget F-94000 Creteil / FR
	[1985/08]
Representative(s)	Gutmann, Ernest, et al Ernest Gutmann - Yves Plasseraud S.A.S. 3, rue Auber 75009 Paris / FR
	[N/P]
Former [1985/48]	Gutmann, Ernest, et al Ernest Gutmann - Yves Plasseraud S.A. 3, rue Chauveau-Lagarde F-75008 Paris / FR
Former [1985/08]	Gutmann, Ernest Ernest Gutmann - Yves Plasseraud S.A. 3, rue Chauveau-Lagarde F-75008 Paris / FR
Application number, filing date	84401593.3	30.07.1984
	[1985/08]
Priority number, date	FR19830012597	29.07.1983 Original published format: FR 8312597
	[1985/08]
Filing language	FR
Procedural language	FR
Publication	Type:	A2 Application without search report
	No.:	EP0133403
	Date:	20.02.1985
	Language:	FR
	[1985/08]
	Type:	A3 Search report
	No.:	EP0133403
	Date:	14.01.1987
	Language:	FR
	[1987/03]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	26.11.1986
Classification	IPC:	C12N15/00, C12P21/02, C07K7/04, C07H21/04, C12N1/20, A61K39/05, A61K39/385, // (C12N1/20, C12R1:16, 1:19)	[1985/08]
	CPC:	C07K14/005 (EP); C07K14/34 (EP); C12N15/70 (EP); C12N15/77 (EP); C07K2319/00 (EP); C07K2319/02 (EP); (+) C07K2319/61 (EP); C12N2730/10122 (EP) (-)
Designated contracting states	AT, BE, CH, DE, GB, IT, LI, LU, NL, SE [1985/08]
Title	German:	Für das Signalpeptid von Diphtherie-Toxin kodierende Nukleotid-Sequenz, diese Nukleotid-Sequenz enthaltender Vektor, deren Verwendung bei der Transformation von Mikroorganismen und die erhaltenen Peptid-Zusammensetzungen	[1985/08]
	English:	Necleotide sequence coding for the signal peptide of diphteria toxine, vector containing this nucleotide sequence, its use in the transformation of microorganisms and peptide compositions obtained	[1985/08]
	French:	Séquence nucléotidique codant pour le peptide signal de la toxine diphtérique, vecteur contenant cette séquence nucléotidique, leur application à la transformation de micro-organismes et compositions peptidiques obtenues	[1985/08]
File destroyed:	12.06.1999
Examination procedure	09.07.1987	Examination requested [1987/36]
	22.03.1989	Despatch of a communication from the examining division (Time limit: M04)
	13.11.1989	Reply to a communication from the examining division
	04.07.1990	Despatch of a communication from the examining division (Time limit: M04)
	28.02.1991	Reply to a communication from the examining division
	24.07.1991	Despatch of a communication from the examining division (Time limit: M04)
	20.01.1992	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
	03.02.1992	Reply to a communication from the examining division
	27.03.1992	Despatch of a communication from the examining division (Time limit: M02)
	09.06.1992	Reply to a communication from the examining division
	08.09.1992	Despatch of communication of intention to grant (Approval: )
	21.04.1993	Despatch of communication that the application is refused, reason: formalities examination [1993/38]
	01.05.1993	Application refused, date of legal effect [1993/38]
Request for further processing for:	29.02.1992	Request for further processing filed
	20.02.1992	Full payment received (date of receipt of payment) Request granted
	12.03.1992	Decision despatched
Fees paid	Renewal fee
	28.07.1986	Renewal fee patent year 03
	20.07.1987	Renewal fee patent year 04
	15.07.1988	Renewal fee patent year 05
	14.07.1989	Renewal fee patent year 06
	19.07.1990	Renewal fee patent year 07
	17.07.1991	Renewal fee patent year 08
	17.07.1992	Renewal fee patent year 09
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[XP]WO8303971 ;
		[A]EP0006694
		[X] - SCIENCE, vol. 220, 29 avril 1983, pages 515-517, Washington, D.C., US; D. LEONG et al.: "Cloned fragment A of diphtheria toxin is expressed and secreted into the periplasmic space of Escherichia coli K12"
		[XD] - JOURNAL OF BACTERIOLOGY, vol. 141, no. 1, janvier 1980, pages 184-189; W.P. SMITH et al.: "Precursor in cotranslational secretion of diphtheria toxin"
		[XP] - SCIENCE, vol. 221, 26 août 1983, pages 855-858; M. KACZOREK et al.: "Nucleotide sequence and expression of the Diphtheria tox228 gene in Escherichia coli"
		[A] - JOURNAL OF VIROLOGY, vol. 42, no. 2, mai 1982, pages 510-518; J.L. MICHEL et al.: "Restriction endonuclease map of the nontoxigenic corynephage gamma-c and its relationship to the toxigenic corynephage beta-c"
		[A] - JOURNAL OF BACTERIOLOGY, vol. 148, no. 1, octobre 1981, pages 153-162; G.A. BUCK et al.: "Identification of deoxyribonucleic acid restriction fragments of beta-converting corynebacteriophages that carry the gene for diphtheria toxin"
		[A] - JOURNAL OF BACTERIOLOGY, vol. 148, octobre 1981, pages 124-130; J.J. COSTA et al.: "Restriction map of corynebacteriophages beta-c and beta-vir and physical localization of the diphtheria tox operon"
		[A] - JOURNAL OF BACTERIOLOGY, vol. 141, mars 1980, pages 1142-1147; W.P. SMITH: "Cotranslational secretion of diphtheria toxin and alkaline phosphatase in vitro: Involvement of membrane protein"

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