Extract from the Register of European Patents

EP About this file: EP0155096

EP0155096 - 17 Beta-Substituted-4-aza-5-alpha-androstenones and their use as 5-alpha-reductase inhibitors [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  26.07.1990
Database last updated on 26.03.2026
Most recent event   Tooltip26.07.1990No opposition filed within time limitpublished on 12.09.1990 [1990/37]
Applicant(s)For all designated states
Merck & Co., Inc.
126, East Lincoln Avenue P.O. Box 2000 Rahway
New Jersey 07065-0900 / US
[N/P]
Former [1985/38]For all designated states
MERCK & CO. INC.
126, East Lincoln Avenue P.O. Box 2000
Rahway New Jersey 07065-0900 / US
Inventor(s)01 / Rasmusson, Gary H.
155 Park Place
Watchung New Jersey 07060 / US
02 / Reynolds, Glenn F.
252 Edgewood Avenue
Westfield New Jersey 07090 / US
[1985/38]
Representative(s)Crampton, Keith John Allen, et al
D. YOUNG & CO. 21 New Fetter Lane
London EC4A 1DA / GB
[1985/38]
Application number, filing date85301122.920.02.1985
[1985/38]
Priority number, dateUS1984058406227.02.1984         Original published format: US 584062
US1984058406127.02.1984         Original published format: US 584061
[1985/38]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0155096
Date:18.09.1985
Language:EN
[1985/38]
Type: A3 Search report 
No.:EP0155096
Date:02.07.1986
Language:EN
[1986/27]
Type: B1 Patent specification 
No.:EP0155096
Date:04.10.1989
Language:EN
[1989/40]
Search report(s)(Supplementary) European search report - dispatched on:EP14.05.1986
ClassificationIPC:C07J73/00, A61K31/435
[1985/38]
CPC:
C07C62/38 (EP); C07D213/00 (KR); A61P5/00 (EP);
C07D221/18 (KR); C07J73/005 (EP); C07C2603/16 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1985/38]
TitleGerman:17 Beta-substituierte-4-aza-5-alpha-Androstenone und ihre Anwendung als 5-alpha-Reduktase-Inhibitoren[1985/38]
English:17 Beta-Substituted-4-aza-5-alpha-androstenones and their use as 5-alpha-reductase inhibitors[1985/38]
French:4-Aza-5 alpha androsténones substitués en 17 bêta et leur utilisation comme inhibiteurs de 5 alpha réductase[1985/38]
MiscellaneousEPB 1989/40: Teilanmeldung 88119105.0 eingereicht am 20/02/85
EPB 1989/40: Divisional application 88119105.0 filed on 20/02/85
EPB 1989/40: Demande divisionnaire 88119105.0 déposée le 20/02/85
Examination procedure15.11.1986Examination requested  [1987/03]
16.10.1987Despatch of a communication from the examining division (Time limit: M04)
19.02.1988Reply to a communication from the examining division
21.07.1988Despatch of a communication from the examining division (Time limit: M04)
17.11.1988Reply to a communication from the examining division
04.01.1989Despatch of communication of intention to grant (Approval: No)
03.04.1989Despatch of communication of intention to grant (Approval: later approval)
11.04.1989Communication of intention to grant the patent
22.05.1989Fee for grant paid
22.05.1989Fee for publishing/printing paid
Divisional application(s)EP88119105.0  / EP0314199
Opposition(s)05.07.1990No opposition filed within time limit [1990/37]
Fees paidRenewal fee
24.02.1987Renewal fee patent year 03
10.02.1988Renewal fee patent year 04
12.02.1989Renewal fee patent year 05
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Documents cited:Search[X]   CHEMICAL ABSTRACTS, vol. 95, no. 13, 28th September 1981, page 99, abstract no. 109055j, Columbus, Ohio, US; T. LIANG et al.: "Inhibition of 5alpha-reductase, receptor binding, and nuclear uptake of androgens in the prostate by a 4-methyl-4-aza-steroid", & J. BIOL. CHEM. 1981, 256(15), 7998-8005 [X]
 [A]   JOURNAL OF ORGANIC CHEMISTRY, vol. 46, no. 7, July 1981, pages 1442-1446, American Chemical Society, Washington, D.C., US; T.G. BACK: "Oxidation of azasteroid lactams and alcohols with benzeneseleninic anhydride" [A]
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