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Extract from the Register of European Patents

EP About this file: EP0194276

EP0194276 - PRODUCTION OF CHIMERIC ANTIBODIES [Right-click to bookmark this link]
StatusPatent maintained as amended
Status updated on  30.11.2001
Database last updated on 23.04.2024
Most recent event   Tooltip19.09.2008Change - opposition data/opponents data or that of the opponents representativepublished on 22.10.2008  [2008/43]
Applicant(s)For all designated states
CELLTECH THERAPEUTICS LIMITED
208 Bath Road Slough
Berkshire SL1 3WE / GB
[N/P]
Former [2002/03]For all designated states
CELLTECH THERAPEUTICS LIMITED
208 Bath Road
Slough, Berkshire SL1 3WE / GB
Former [1997/39]For all designated states
CELLTECH THERAPEUTICS LIMITED
216 Bath Road
Slough, Berkshire SL1 4EN / GB
Former [1986/38]For all designated states
CELLTECH LIMITED
244-250 Bath Road
Slough Berkshire SL1 4DY / GB
Inventor(s)01 / NEUBERGER, Michael, Samuel
34 Bateman Street
Cambridge CB2 1MA / GB
02 / RABBITTS, Terence, Howard
Woodside, High Street
Hildersham Cambridge CB1 6BU / GB
[1986/38]
Representative(s)Mercer, Christopher Paul, et al
Carpmaels & Ransford LLP
One Southampton Row
London
WC1B 5HA / GB
[N/P]
Former [2001/17]Mercer, Christopher Paul, et al
Carpmaels & Ransford 43, Bloomsbury Square
London WC1A 2RA / GB
Former [1986/38]Votier, Sidney David, et al
CARPMAELS & RANSFORD 43, Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date85904274.903.09.1985
[1986/38]
WO1985GB00392
Priority number, dateGB1984002223803.09.1984         Original published format: GB 8422238
[1986/38]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO8601533
Date:13.03.1986
Language:EN
[1986/06]
Type: A1 Application with search report 
No.:EP0194276
Date:17.09.1986
Language:EN
The application published by WIPO in one of the EPO official languages on 13.03.1986 takes the place of the publication of the European patent application.
[1986/38]
Type: B1 Patent specification 
No.:EP0194276
Date:11.08.1993
Language:EN
[1993/32]
Type: B2 New European patent specification 
No.:EP0194276
Date:16.01.2002
Language:EN
[2002/03]
Search report(s)International search report - published on:EP13.03.1986
ClassificationIPC:C12N15/13, C12N15/62, A61K39/395, C12P21/00, G01N33/563
[1993/32]
CPC:
C07K16/44 (EP); C07K16/462 (EP); G01N33/531 (EP);
G01N33/563 (EP); C07K2317/24 (EP); C07K2319/00 (EP);
C07K2319/30 (EP) (-)
Former IPC [1986/38]C12N15/00, C07K15/00, A61K39/395, C07K3/18, C12N5/00, C12P21/00, G01N33/563
Designated contracting statesAT,   BE,   CH,   DE,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1986/38]
TitleGerman:HERSTELLUNG VON CHIMÄREN ANTIKÖRPERN[1993/32]
English:PRODUCTION OF CHIMERIC ANTIBODIES[1986/38]
French:PRODUCTION D'ANTICORPS CHIMERIQUES[1986/38]
Former [1986/38]HERSTELLUNG VON SCHIMÄRISCHEN ANTIKÖRPERN
Entry into regional phase18.04.1986National basic fee paid 
18.04.1986Designation fee(s) paid 
18.04.1986Examination fee paid 
Examination procedure18.04.1986Examination requested  [1986/38]
20.05.1988Despatch of a communication from the examining division (Time limit: M07)
29.12.1988Reply to a communication from the examining division
12.07.1989Despatch of a communication from the examining division (Time limit: M04)
17.11.1989Reply to a communication from the examining division
10.05.1990Despatch of a communication from the examining division (Time limit: M06)
13.11.1990Reply to a communication from the examining division
19.02.1991Despatch of a communication from the examining division (Time limit: M04)
19.06.1991Reply to a communication from the examining division
14.10.1991Despatch of a communication from the examining division (Time limit: M04)
14.02.1992Reply to a communication from the examining division
25.03.1992Despatch of communication of intention to grant (Approval: Yes)
26.11.1992Despatch of communication that the application is refused, reason: formalities examination {1}
17.02.1993Communication of intention to grant the patent
13.04.1993Fee for grant paid
13.04.1993Fee for publishing/printing paid
Opposition(s)Opponent(s)01  11.05.1994  26.05.1994  ADMISSIBLE
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
 02  11.05.1994  27.07.1994  ADMISSIBLE
Aventis Pharma Deutschland GmbH
65926 Frankfurt am Main / DE
Opponent's representative
Müller-Gerger, Thomas
Aventis Pharma Deutschland GmbH
Patent- und Lizenzabteilung
65926 Frankfurt am Main / DE
 03  11.05.1994  24.06.1994  ADMISSIBLE
Roche Diagnostics GmbH
Sandhoferstr. 116
68305 Mannheim / DE
Opponent's representative
Schreiner, Siegfried, et al, et al
Roche Diagnostics GmbH Patent Department (TR-E) Nonnenwald 2
82377 Penzberg / DE
 [N/P]
Former [2008/43]
Opponent(s)01  11.05.1994  26.05.1994  ADMISSIBLE
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
Vossius & Partner
Postfach 86 07 67
81634 München / DE
 02  11.05.1994  27.07.1994  ADMISSIBLE
Aventis Pharma Deutschland GmbH
65926 Frankfurt am Main / DE
Opponent's representative
Müller-Gerger, Thomas, Dr.
Aventis Pharma Deutschland GmbH, Patent- und Lizenzabteilung
65926 Frankfurt am Main / DE
 03  11.05.1994  24.06.1994  ADMISSIBLE
Roche Diagnostics GmbH
Sandhoferstr. 116
68305 Mannheim / DE
Opponent's representative
Schreiner, Siegfried, et al, et al
Roche Diagnostics GmbH Patent Department (TR-E) Nonnenwald 2
82377 Penzberg / DE
Former [2008/35]
Opponent(s)01  11.05.1994  26.05.1994  ADMISSIBLE
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
Vossius & Partner
Postfach 86 07 67
81634 München / DE
 02  11.05.1994  27.07.1994  ADMISSIBLE
Aventis Pharma Deutschland GmbH
65926 Frankfurt am Main / DE
Opponent's representative
Müller-Gerger, Thomas, Dr.
Aventis Pharma Deutschland GmbH, Patent- und Lizenzabteilung
65926 Frankfurt am Main / DE
 03  11.05.1994  24.06.1994  ADMISSIBLE
Roche Diagnostics GmbH
Sandhoferstr. 116
68305 Mannheim / DE
Opponent's representative
Schreiner, Siegfried, et al, et al
Roche Diagnostics GmbH, Werk Penzberg, Abt. GE-TB, Postfach 11 52
82372 Penzberg / DE
Former [2001/24]
Opponent(s)01  11.05.1994  26.05.1994  ADMISSIBLE
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
VOSSIUS & PARTNER
P.O. Box 86 07 67
D-81634 München / DE
 02  11.05.1994  27.07.1994  ADMISSIBLE
Aventis Pharma Deutschland GmbH
65926 Frankfurt am Main / DE
Opponent's representative
Müller-Gerger, Thomas, Dr.
Aventis Pharma Deutschland GmbH, Patent- und Lizenzabteilung
65926 Frankfurt am Main / DE
 03  11.05.1994  24.06.1994  ADMISSIBLE
Roche Diagnostics GmbH
Sandhoferstr. 116
68305 Mannheim / DE
Opponent's representative
Schreiner, Siegfried, et al, et al
Roche Diagnostics GmbH, Werk Penzberg, Abt. GE-TB, Postfach 11 52
82372 Penzberg / DE
Former [1999/37]
Opponent(s)01  11.05.1994  26.05.1994  ADMISSIBLE
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
VOSSIUS & PARTNER
P.O. Box 86 07 67
D-81634 München / DE
 02  11.05.1994  27.07.1994  ADMISSIBLE
HOECHST AKTIENGESELLSCHAFT
65926 Frankfurt am Main / DE
Opponent's representative
Müller-Gerger, Thomas, Dr.
Hoechst Marion Roussel Deutschland GmbH Patent- und Lizenzabteilung Gebäude K 801
65926 Frankfurt am Main / DE
 03  11.05.1994  24.06.1994  ADMISSIBLE
Roche Diagnostics GmbH
Sandhoferstr. 116
68305 Mannheim / DE
Opponent's representative
Schreiner, Siegfried, et al, et al
Roche Diagnostics GmbH, Werk Penzberg, Abt. GE-TB, Postfach 11 52
82372 Penzberg / DE
Former [1999/15]
Opponent(s)01  11.05.1994  26.05.1994  ADMISSIBLE
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
VOSSIUS & PARTNER
P.O. Box 86 07 67
D-81634 München / DE
 02  11.05.1994  27.07.1994  ADMISSIBLE
Behringwerke Aktiengesellschaft
Emil-von-Behring-Strasse 76
35041 Marburg / DE
Opponent's representative
Lauppe, Hans Friedrich (DE)
Behringwerke AG Postfach 11 40
D-35001 Marburg / DE
 03  11.05.1994  24.06.1994  ADMISSIBLE
Roche Diagnostics GmbH
Sandhoferstr. 116
68305 Mannheim / DE
Opponent's representative
Schreiner, Siegfried, et al, et al
Roche Diagnostics GmbH, Werk Penzberg, Abt. GE-TB, Postfach 11 52
82372 Penzberg / DE
Former [1995/27]
Opponent(s)01  11.05.1994  26.05.1994  ADMISSIBLE
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
VOSSIUS & PARTNER
P.O. Box 86 07 67
D-81634 München / DE
 02  11.05.1994  27.07.1994  ADMISSIBLE
Behringwerke Aktiengesellschaft
Emil-von-Behring-Strasse 76
35041 Marburg / DE
Opponent's representative
Lauppe, Hans Friedrich (DE)
Behringwerke AG Postfach 11 40
D-35001 Marburg / DE
 03  11.05.1994  24.06.1994  ADMISSIBLE
BOEHRINGER MANNHEIM GMBH Werk Penzberg Abt. GE-TB, Dr. Schreiner
Postfach 1152
82372 Penzberg / DE
Former [1994/27]
Opponent(s)01  11.05.1994   
Xoma Corp.
2910 Seventh St.
Berkeley, California 94710 / US
Opponent's representative
VOSSIUS & PARTNER
P.O. Box 86 07 67
D-81634 München / DE
 02  11.05.1994   
Behringwerke Aktiengesellschaft
Emil-von-Behring-Strasse 76
35041 Marburg / DE
Opponent's representative
Lauppe, Hans Friedrich (DE)
Behringwerke AG Postfach 11 40
D-35001 Marburg / DE
 03  11.05.1994   
Boehringer Mannheim GmbH Patentabteilung
Sandhofer Strasse 116
D-68298 Mannheim / DE
24.05.1994No. 02: Notification indicating deficiencies in the notice of opposition
26.05.1994No. 01: Notification indicating deficiencies in the notice of opposition
26.05.1994No. 03: Notification indicating deficiencies in the notice of opposition
01.06.1994No. 01: Reply to notification indicating deficiencies in the notice of opposition
08.06.1994No. 03: Reply to notification indicating deficiencies in the notice of opposition
08.07.1994No. 02: Reply to notification indicating deficiencies in the notice of opposition
01.08.1994Invitation to proprietor to file observations on the notice of opposition
05.04.1995Reply of patent proprietor to notice(s) of opposition
12.11.1996Date of oral proceedings
26.11.1996Despatch of a communication from the opposition division (Time limit: M04)
26.11.1996Despatch of minutes of oral proceedings
23.01.1997Reply to a communication from the opposition division
24.04.1997Despatch of interlocutory decision in opposition
03.05.2001Legal effect of interlocutory decision in opposition
13.07.2001Despatch of communication that the patent will be maintained as amended
07.09.2001Fee for printing new specification paid
Appeal following opposition10.06.1997Appeal received No.  T0669/97
04.09.1997Statement of grounds filed
03.05.2001Result of appeal procedure: continuation of opposition procedure
03.05.2001Date of oral proceedings
16.05.2001Minutes of the oral proceedings despatched
Request for further processing for:28.01.1993Request for further processing filed
29.01.1993Full payment received (date of receipt of payment)
Request granted
12.02.1993Decision despatched
Fees paidRenewal fee
18.09.1987Renewal fee patent year 03
14.09.1988Renewal fee patent year 04
11.09.1989Renewal fee patent year 05
21.09.1990Renewal fee patent year 06
09.09.1991Renewal fee patent year 07
28.09.1992Renewal fee patent year 08
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Cited inInternational searchEP0068763  [ ] (UNIV TEXAS [US]);
 EP0090898  [ ] (GENETIC SYSTEMS CORP [US]);
 WO8303971  [ ] (HARVARD COLLEGE [US]);
 WO8400382  [ ] (US HEALTH [US]);
 EP0105521  [ ] (TAKEDA CHEMICAL INDUSTRIES LTD [JP]);
 EP0120694  [ ] (CELLTECH LTD [GB]);
 EP0150126  [ ] (IMMUNEX CORP [US]);
 EP0125023  [ ]
 [A]  - CHEMICAL ABSTRACTS, Volume 95, No. 4, 27 July 1981, Columbus, Ohio (US) V. RASO et al.: "Hybrid Antibodies with Dual Specificity for the Delivery of Ricin to Immunoglobulin-Bearing Target Cells", see page 363, Abstract 30711m, & Cancer Res. 1981, 41(6) 2073-8 (Eng.)
 [XP]  - Nature, 314, No. 6010, April 1985 London (GB) SHUN-ICHI TAKEDA et al.: "Construction of Chimaeric Processed Immunoglobulin Genes Containing Mouse Variable and Juman Constant Region Sequences", pages 452-454, see the whole article
 [XP]  - Nature 314, No. 6008, 21st March 1985 London (GB) M. NEUBERGER et al.: "A Hapten-Specific Chimaeric Ig E Antibody with Human Physiological Effector Function", pages 268-270, see the whole article
 [XP]  - Nature 312, No. 5995, December 1984 London (GB) G. BOULIANNE et al.: "Production of Functional Chimaeric Mouse/Human Antibody", pages 643-646, see the whole article
 [XP]  - Nature 312, No. 5995, December 1984 London (GB) M. NEUBERGER et al.: "Recombinant Antibodies Possessing Novel Effector Functions", pages 604-608, see the whole article
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.