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EP About this file: EP0260312

EP0260312 - METHOD FOR BLOCKING CALCIUM CHANNELS [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 08.08.1991 Database last updated on 11.09.2024
Most recent event Tooltip	07.07.2007	Change - inventor	published on 08.08.2007 [2007/32]
Applicant(s)	For all designated states NEW YORK UNIVERSITY 70 Washington Square South New York, NY 10012 / US
	[1988/12]
Inventor(s)	01 / LLINAS, Rodolfo, R. 16 Sutton Place, 7A New York, NY 10021 / US
	02 / YAROM, Yosef 25 Kubovi Street Jerusalem / IL
	[1988/12]
Representative(s)	Grünecker Patent- und Rechtsanwälte PartG mbB Leopoldstrasse 4 80802 München / DE
	[N/P]
Former [1988/12]	Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät Maximilianstrasse 58 D-80538 München / DE
Application number, filing date	87902204.4	23.02.1987
	[1988/12]
	WO1987US00413
Priority number, date	US19860837088	06.03.1986 Original published format: US 837088
	[1988/12]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO8705214
	Date:	11.09.1987
	Language:	EN
	[1987/20]
	Type:	A1 Application with search report
	No.:	EP0260312
	Date:	23.03.1988
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 11.09.1987 takes the place of the publication of the European patent application.
	[1988/12]
Search report(s)	International search report - published on:	US	11.09.1987
	(Supplementary) European search report - dispatched on:	EP	07.11.1989
Classification	IPC:	A61K31/045	[1988/12]
	CPC:	A61K31/045 (EP)
Designated contracting states	AT, BE, CH, DE, FR, GB, IT, LI, LU, NL, SE [1988/12]
Title	German:	VERFAHREN ZUM BLOCKIEREN VON KALZIUMKANÄLEN	[1988/12]
	English:	METHOD FOR BLOCKING CALCIUM CHANNELS	[1988/12]
	French:	PROCEDE DE BLOCAGE DE CANAUX DE CALCIUM	[1988/12]
File destroyed:	05.08.1997
Entry into regional phase	02.11.1987	National basic fee paid
	02.11.1987	Search fee paid
	02.11.1987	Designation fee(s) paid
	02.11.1987	Examination fee paid
Examination procedure	02.11.1987	Examination requested [1988/12]
	30.10.1990	Despatch of a communication from the examining division (Time limit: M04)
	12.03.1991	Application deemed to be withdrawn, date of legal effect [1991/39]
	12.04.1991	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [1991/39]
Fees paid	Renewal fee
	28.02.1989	Renewal fee patent year 03
	22.01.1990	Renewal fee patent year 04
	02.01.1991	Renewal fee patent year 05
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[ ] - Therapie, Vol. 32, 1977, pages 355-364; O. SPREUX-VAROQUAUX et al.: "Ethanol et tremblements experimentaux chez la souris et le rat", Summary; figures 2,3; page 362lines 24-33.
		[ ] - Fed. Proc., Vol. 36, No. 3, 1977, page 353, Abstract 444; W.D. KNOWLES et al.: "Effects of amesthetics on cerebellar neuroms recorded chromically after harmaline"whole Abstract.
		[ ] - Life Sciences, Vol. 34, January 1984, pages 49-56, Pergamon Press, US; M.S. RAPPAPORT et al.: "Ethanol effects on harmaline-induced tremor and increase of cerebellar cyclic GMP", Summary; figures 1,2; pages 51,52, section "Results", page 54last paragraph.
		[ ] - Can. J. Physiol. Pharmacol., Vol. 60, No. 5, May 1982, pages 610-614, Nat. Research Council of Canada, J.G. SINCLAIR et al.: "Ethanol effects on the olivocerebellar system", Summary, page 610, section "Introduction"; figure 2; page 612, right-hand column, lines 12-16; page 613, right-hand column, line 10 - page 614, left-hand columnline 6.
		[ ] - J. Pharm. Exp. Ther., Vol. 225, No. 8, 1983, pages 571-575, US; S.W. LESLIE et al.: "Inhibition of fast- and slow-phase depolarization-dependent synaptosomal calcium uptake by ethanol", Abstract; table 1; pages 572-573, section "Results"; page 573, right-hand column, line 18 - page 574, left-hand columnline 3.
		[ ] - Biochem. Pharmacology, Vol. 32, No. 6, 1983, pages 963-969, Pergamon Press Ltd., GB; M.L. MICHAELIS et al.: "Alcohol and local anesthetic effects on Na dependent Ca2+ fluxes in brain synaptic membrane vesicles", Abstract; figures 2,3,4a,4b; page 965, left-hand column, line 1 - page 965, right-hand column, line 47; page 967, right-hand column, line 50 - page 968, left-hand columnline 2.
		[ ] - Soc. Neurosci. Abstr., Vol. 12, No. 1, November 1986, page 174; Abstr. 49.3, R. LLINAS et al.: "Specific blockage of the low threshold calcium channel by high molecular weight alcohols"whole Abstract.
		[ ] - Pfluegers Arch, Vol. 414, No. 1, May 1989, pages 31-36, European Journal of Physiology, Springer Verlag, DE, C.M. SINTON et al.: "The effectiveness of different isomers of octanol as blockers of harmalinc-induced tremor", Abstract; page 34, left-hand column, line 9 - page 34, right-hand column, line 27; page 36, left-hand columnlines 7-47.
	International search	[X]US2903396 (CLARKE SAUNDERS JOHN, et al);
		[X]US3041237 (HOFF DONALD A, et al);
		[X]US3778509 (LOYD LEWIS H)
		[X] - Merck Index, 9th Ed (1976)page 879

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