EP About this file: EP0278776

EP0278776 - Methods and deoxyribonucleic acid for the preparation of tissue factor protein [Right-click to bookmark this link]
Status	Patent maintained as amended Status updated on 27.02.2004 Database last updated on 05.04.2025
Most recent event Tooltip	05.10.2005	Change: Appeal number
Applicant(s)	For all designated states Genentech, Inc. 460 Point San Bruno Boulevard South San Francisco CA 94080 / US
	[N/P]
Former [1988/33]	For all designated states GENENTECH, INC. 460 Point San Bruno Boulevard South San Francisco California 94080 / US
Inventor(s)	01 / Lawn, Richard Mark 1927 8th Avenue San Francisco, CA 94116 / US
	02 / Wion, Karen Lynne 663 Santa Barbara Avenue Millbrae, CA 94030 / US
	03 / Vehar, Gorden Allen 110 Leslie Drive San Carlos, CA 94070 / US
	[1997/22]
Former [1988/33]	01 / Lawn, Richard Mark 1927 8th Avenue San Francisco California 94116 / US
	02 / Wion, Karen Lynne 663 Santa Barbara Avenue Millbrae California 94030 / US
	03 / Vehar, Gorden Allen 110 Leslie Drive San Carlos California 94070 / US
Representative(s)	Miles, John Stephen, et al Potter Clarkson LLP The Belgrave Centre Talbot Street Nottingham NG1 5GG / GB
	[N/P]
Former [2003/31]	Miles, John Stephen, et al Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD / GB
Former [1997/22]	Bassett, Richard Simon, et al ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate Nottingham NG1 1LE / GB
Former [1988/33]	Armitage, Ian Michael, et al MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP / GB
Application number, filing date	88301190.0	12.02.1988
	[1988/33]
Priority number, date	US19870013743	12.02.1987 Original published format: US 13743
	US19870035409	07.04.1987 Original published format: US 35409
	US19880152698	05.02.1988 Original published format: US 152698
	[1988/33]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	EP0278776
	Date:	17.08.1988
	Language:	EN
	[1988/33]
	Type:	A3 Search report
	No.:	EP0278776
	Date:	13.09.1989
	Language:	EN
	[1989/37]
	Type:	B1 Patent specification
	No.:	EP0278776
	Date:	28.05.1997
	Language:	EN
	[1997/22]
	Type:	B2 New European patent specification
	No.:	EP0278776
	Date:	14.04.2004
	Language:	EN
	[2004/16]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	26.07.1989
Classification	IPC:	C12N15/12, C07K14/745, C12N5/10, C12N1/21	[1997/22]
	CPC:	C12N15/85 (EP); A61P7/04 (EP); C07K14/005 (EP); C07K14/475 (EP); C07K14/745 (EP); C12N9/6429 (EP); (+) C12Y304/21005 (EP); A61K38/00 (EP); C07K2319/00 (EP); C07K2319/02 (EP); C07K2319/32 (EP); C07K2319/50 (EP); C12N2710/16622 (EP); C12N2800/108 (EP); C12N2830/42 (EP); C12N2840/44 (EP) (-)
	Former IPC [1988/33]	C12N15/00, C12P21/02, C12N5/00, C12N1/20, C07K13/00, A61K37/02
Designated contracting states	AT, BE, CH, DE, ES, FR, GB, GR, IT, LI, LU, NL, SE [1988/33]
Title	German:	Verfahren und Desoxyribonukleinsäure zur Herstellung von Gewebefaktor-Protein	[1988/33]
	English:	Methods and deoxyribonucleic acid for the preparation of tissue factor protein	[1988/33]
	French:	Méthodes et acide desoxyribonucléique pour la préparation de la protéine du facteur tissulaire	[1988/33]
Miscellaneous	EPB 2004/16: (deleted)
	EPB 2004/16: (deleted)
	EPB 2004/16: (deleted)
	EPB 1997/15: Teilanmeldung 97200009.5 eingereicht am 03/01/97
	EPB 1997/15: Divisional application 97200009.5 filed on 03/01/97
	EPB 1997/15: Demande divisionnaire 97200009.5 déposée le 03/01/97
Examination procedure	deleted	Decision about request for accelerated examination - accepted: No
	03.03.1990	Examination requested [1990/18]
	05.06.1992	Despatch of a communication from the examining division (Time limit: M06)
	15.01.1993	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
	17.03.1993	Reply to a communication from the examining division
	04.10.1993	Despatch of a communication from the examining division (Time limit: M06)
	12.04.1994	Reply to a communication from the examining division
	16.06.1994	Despatch of a communication from the examining division (Time limit: M04)
	20.10.1994	Reply to a communication from the examining division
	18.01.1995	Request for accelerated examination filed
	16.02.1995	Despatch of a communication from the examining division (Time limit: M04)
	08.06.1995	Reply to a communication from the examining division
	24.07.1995	Despatch of a communication from the examining division (Time limit: M02)
	05.09.1995	Reply to a communication from the examining division
	04.12.1995	Despatch of a communication from the examining division (Time limit: M06)
	12.06.1996	Reply to a communication from the examining division
	19.12.1996	Despatch of communication of intention to grant (Approval: Yes)
	14.01.1997	Communication of intention to grant the patent
	21.03.1997	Fee for grant paid
	21.03.1997	Fee for publishing/printing paid
Divisional application(s)	EP97200009.5 / EP0787802
Opposition(s)	Opponent(s)	01 23.02.1998 Diagnostica Stago 9, rue des Frères Chausson BP 226 92602 Asnieres / FR Opponent's representative Robert, Jean-Pierre Cabinet Boettcher 16, rue Médéric 75017 Paris / FR
		02 27.02.1998 ADMISSIBLE The Scripps Research Institute 10666 North Torrey Pines Road La Jolla, California 92037 / US Opponent's representative Vossius, Volker ZSP Patentanwälte PartG mbB Radlkoferstrasse 2 81373 München / DE
		[N/P]
	Former [1998/17]
	Opponent(s)	01 23.02.1998 Diagnostica Stago 9, rue des Frères Chausson BP 226 92602 Asnieres / FR Opponent's representative Robert, Jean-Pierre Cabinet Boettcher 16, rue Médéric 75017 Paris / FR
		02 27.02.1998 ADMISSIBLE The Scripps Research Institute 10666 North Torrey Pines Road La Jolla, California 92037 / US Opponent's representative Vossius, Volker Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6 81679 München / DE
	Former [1998/16]
	Opponent(s)	01 23.02.1998 WITHDRAWN Diagnostica Stago 9, rue des Frères Chausson BP 226 92602 Asnieres / FR Opponent's representative Robert, Jean-Pierre Cabinet Boettcher 16, rue Médéric 75017 Paris / FR
	07.04.1998	Invitation to proprietor to file observations on the notice of opposition
	27.11.1998	Reply of patent proprietor to notice(s) of opposition
	16.05.2000	Date of oral proceedings
	29.06.2000	Despatch of a communication from the opposition division (Time limit: M02)
	29.06.2000	Despatch of minutes of oral proceedings
	22.08.2000	Reply to a communication from the opposition division
	29.01.2001	Despatch of interlocutory decision in opposition
	02.07.2003	Legal effect of interlocutory decision in opposition
	14.11.2003	Despatch of communication that the patent will be maintained as amended
	05.02.2004	Fee for printing new specification paid
Appeal following opposition	20.03.2001	Appeal received No. T0351/01
	08.06.2001	Statement of grounds filed
	02.07.2003	Result of appeal procedure: maintenance in amended form
	02.07.2003	Date of oral proceedings
	09.07.2003	Minutes of the oral proceedings despatched
Request for further processing for:	17.03.1993	Request for further processing filed
	17.03.1993	Full payment received (date of receipt of payment) Request granted
	02.04.1993	Decision despatched
Fees paid	Renewal fee
	18.01.1990	Renewal fee patent year 03
	21.01.1991	Renewal fee patent year 04
	20.01.1992	Renewal fee patent year 05
	08.02.1993	Renewal fee patent year 06
	25.02.1994	Renewal fee patent year 07
	24.02.1995	Renewal fee patent year 08
	26.02.1996	Renewal fee patent year 09
	26.02.1997	Renewal fee patent year 10
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Documents cited:	Search	[AD]EP0139416 (GENENTECH INC [US]);
		[E]WO8809817 (SINAI SCHOOL MEDICINE [US], et al)
		[ ] - Thrombosis and Haemostasis, Vol. 58, No. 1, January 1987, page 258, Ref. No. 941; Stuttgart, DE, T.S. EDGINGTON et al.: "Molecular cloning of human tissue factor cDNA", Abstract.
		[ ] - Proc. Natl. Acad. Sci. USA, Vol. 83, January 1986, Biochemistry, pages 299-302; Washington, US, A. GUHA et al.: "Affinity purification of human tissue factor: Interaction of factor VII and tissue factor in detergent micelles", whole article.
		[ ] - Federation Proceedings, Vol. 46, No. 3, March 1, 1987, page 716, Ref. No. 2338; Bethesda, US, J.H. MORRISSEY et al.: "Molecular cloning of the cDNA for human tissue factor", Abstract.
		[ ] - Federation Proceedings, Vol. 46, No. 6, May 1, 1987, page 2242, Ref. No. 1846, Bethesda, US, E.M. SCARPATI et al.: "Human tissue factor: Cona cloning, primary structure, and chromosome localization", Abstract.
		[ ] - Cell, Vol. 50, July 3, 1987, pages 129-135; Cambridge, US, J.H. MORRISSEY et al.: "Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade", whole article.
		[ ] - Biochemistry, Vol. 26, No. 17, August 25, 1987, pages 5234-5238; Washington, US, E.M. SCARPATI et al.: "Human tissue factor: cDNA sequence and chromosome localization of the gene", whole article.
		[ ] - Proc. Natl. Acad. Sci. USA, Vol. 84, No. 15, August 1987, pages 5148-5152; Washington, US, E.K. SPICER et al.: "Isolation of cDNA clones coding for human tissue factor: Primary structure of the protein and cDNA", whole article.
		[ ] - Thrombosis Research, Vol. 48, No. 1, October 1987, pages 89-99; New York, US, K.L. FISHER et al.: "Cloning and expression of human tissue factor cDNA", whole article.
		[ ] - Federation Proceedings, Vol. 45, No. 6, May 1986, page 1639, Ref. No. 927; Bethesda, US, J.M. KITTLER et al.: "Identification of a cDNA clone for bovine tissue factor", Abstract.

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