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Extract from the Register of European Patents

EP About this file: EP0327378

EP0327378 - Domain-modified constant region antibodies [Right-click to bookmark this link]
Status	Patent revoked Status updated on 17.02.2006 Database last updated on 05.10.2024
Most recent event Tooltip	17.02.2006	Revocation of patent	published on 05.04.2006 [2006/14]
Applicant(s)	For all designated states The Trustees of Columbia University in the City of New York West 116th Street and Broadway New York New York 10027 / US
	[N/P]
Former [1997/38]	For all designated states THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK West 116th Street and Broadway New York, New York 10027 / US
Former [1991/02]	For all designated states THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK West 116th Street and Broadway New York, New York 10027 / US
	For all designated states Becton Dickinson and Company One Becton Drive Franklin Lakes, New Jersey 07417-1880 / US
Former [1989/32]	For all designated states The Trustees of Columbia University in the City of New York Broadway and West 116th Street New York, NY 10027 / US
	For all designated states Becton Dickinson and Company One Becton Drive Franklin Lakes, New Jersey 07417-1880 / US
Inventor(s)	01 / Morrison, Sherie L 31,Claremont Road Scardsdale New York 10583 / US
	02 / Oi, Vernon T. 1259 Marilyn Court Mount View, California 94040 / US
	[1989/32]
Representative(s)	Harrison, David Christopher, et al Mewburn Ellis LLP City Tower 40 Basinghall Street London EC2V 5DE / GB
	[N/P]
Former [1994/28]	Harrison, David Christopher, et al MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP / GB
Former [1989/32]	Harrison, David Christopher MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP / GB
Application number, filing date	89301052.0	03.02.1989
	[1989/32]
Priority number, date	US19880152741	05.02.1988 Original published format: US 152741
	[1989/32]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	EP0327378
	Date:	09.08.1989
	Language:	EN
	[1989/32]
	Type:	B1 Patent specification
	No.:	EP0327378
	Date:	11.12.1996
	Language:	EN
	[1996/50]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	08.06.1989
Classification	IPC:	C12N15/00, C12P21/00	[1989/32]
	CPC:	C07K16/00 (EP)
Designated contracting states	AT, BE, CH, DE, FR, GB, LI, LU, NL [1996/38]
Former [1996/03]	AT, BE, CH, DE, FR, GB, IT, LI, LU, NL, SE
Former [1989/32]	AT, BE, CH, DE, ES, FR, GB, GR, IT, LI, LU, NL, SE
Title	German:	Modifikation der Domäne der Konstantregion der Antikörpern	[1989/32]
	English:	Domain-modified constant region antibodies	[1989/32]
	French:	Modification du domain de la region constant des anticorps	[1989/32]
Examination procedure	09.02.1990	Examination requested [1990/21]
	18.02.1993	Despatch of a communication from the examining division (Time limit: M06)
	29.09.1993	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
	07.12.1993	Reply to a communication from the examining division
	26.05.1994	Despatch of a communication from the examining division (Time limit: M04)
	05.10.1994	Reply to a communication from the examining division
	13.07.1995	Despatch of communication of intention to grant (Approval: No)
	08.05.1996	Despatch of communication of intention to grant (Approval: later approval)
	10.06.1996	Communication of intention to grant the patent
	02.09.1996	Fee for grant paid
	02.09.1996	Fee for publishing/printing paid
Opposition(s)	Opponent(s)	01 09.09.1997 ADMISSIBLE Celltech Therapeutics Ltd 216 Bath Road Slough, Berkshire SL1 4EN / GB Opponent's representative Mercer, Christopher Paul Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB
		[N/P]
	Former [1997/44]
	Opponent(s)	01 09.09.1997 ADMISSIBLE Celltech Therapeutics Ltd 216 Bath Road Slough, Berkshire SL1 4EN / GB Opponent's representative Mercer, Christopher Paul Carpmaels & Ransford One Southampton Row London WC1B 5HA / GB
	20.10.1997	Invitation to proprietor to file observations on the notice of opposition
	30.07.1998	Reply of patent proprietor to notice(s) of opposition
	19.10.2000	Date of oral proceedings
	13.12.2000	Despatch of minutes of oral proceedings
	13.12.2000	Despatch of communication that the patent will be revoked
	29.01.2006	Legal effect of revocation of patent [2006/14]
Appeal following opposition	21.02.2001	Appeal received No. T0236/01
	23.04.2001	Statement of grounds filed
	15.09.2005	Result of appeal procedure: appeal of the proprietor was rejected
Request for further processing for:	07.12.1993	Request for further processing filed
	08.12.1993	Full payment received (date of receipt of payment) Request granted
	27.12.1993	Decision despatched
Fees paid	Renewal fee
	15.02.1991	Renewal fee patent year 03
	10.02.1992	Renewal fee patent year 04
	22.01.1993	Renewal fee patent year 05
	17.01.1994	Renewal fee patent year 06
	19.01.1995	Renewal fee patent year 07
	16.01.1996	Renewal fee patent year 08
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A]EP0184187 (TEIJIN LTD [JP]);
		[A]EP0239400 (WINTER GREGORY PAUL);
		[XP]WO8807089 (MEDICAL RES COUNCIL [GB]);
		[X]EP0125023
		[X] - CHEMICAL ABSTRACTS, vol. 107, no. 7, 17th August 1987, abstract no. 57101r, Columbus, Ohio, US; MARC J. SCHULMAN et al.: "Completement activation by IgM: evidence for the importance of the third constant domain of the u heavy chain", & Eur. J. Immunol. 1987, vol. 17, no. 4, pages 549-554
		[X] - CHEMICAL ABSTRACTS, vol. 100, no. 15, 9th April 1984, abstract no. 119073z, Columbus, Ohio, US; T. OI et al.: "Hybridoma antibody-producing switch variants: a variant lacking the CH1 domain", & Miles Int. Symp. Ser. 1984, vol. 14, pages 281-287
		[X] - CHEMICAL ABSTRACTS, vol. 105, no. 7, 18th August 1986, abstract no. 59187f, Columbus, Ohio, US; G. SARMY et al.: "CH2 and CH3 domain deleted igG1 paraproteins inhibit differently Fc receptor mediated binding and cytolysis", & Immunol. Lett. 1986, vol. 12, no. 5,6, pages 307-312
		[AD] - PROC. NATL. ACAD. SCI. (USA) vol. 81 November 1984, pages 6851-6855. Washington, USA; SHERIE L. MORRISON et al.: "Chimeric human antibody molecules mouse antigen-binding domains with human constant domains".
		[AD] - NATURE, vol. 312, 13th December 1984, pages 604-608, London, GB; MICHAEL S. NEUBERGER et al.: "Recombinant antibodies possessing novel effector functions".
	Examination	- CHEMICAL ABSTRACTS vol. 107, no.7, 17th August 1987, abstract no. 57101r, Columbus, Ohio, US; MARC J. SCHULMAN et al.: & EUR. J. Immunol. 1987, vol. 17, no. 4, pages 549-554
		- CHEMICAL ABSTRACTS vol. 100, no. 15, 9th April 1984, abstract no. 119073z, Columbus, Ohio, US; T. OI et al; & Miles Int. Symp. Ser. 1984, vol. 14, pages 281-287
		- CHEMICAL ABSTRACTS vol. 105, no. 7, 18th August 1986, abstract no. 59187f, Columbus, Ohio, US; G. SARMAY et al; & Immunol. Lett. 1986, vol. 12, no. 5,6, pages 307-312
		- PROC. NATL. ACAD. SCI. USA vol. 81, November 1984, pages 6851-6855, Washington, USA; SHERIE L. MORRISON et al; abstract, figure 1; page 6854c2
		- NATURE vol. 312, 13th December 1984, pages 604-608, London, GB; MICHAEL S. NEUBERGER et al.: abstract, figure 1; page 605c2, page 607

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