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Extract from the Register of European Patents

EP About this file: EP0366451

EP0366451 - The use of oxidized polyamines, especially NN'-Bis-(3-propionaldehyde)-1-4-diaminobutane (sperminedialdehyde) as immunosuppressive agents [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.02.1995
Database last updated on 03.06.2024
Most recent event   Tooltip09.02.1995No opposition filed within time limitpublished on 29.03.1995 [1995/13]
Applicant(s)For all designated states
ORTHO PHARMACEUTICAL CORPORATION
U.S. Route 202 P.O. Box 300 Raritan
New Jersey 08869-0602 / US
[N/P]
Former [1990/18]For all designated states
ORTHO PHARMACEUTICAL CORPORATION
U.S. Route 202 P.O. Box 300
Raritan New Jersey 08869-0602 / US
Inventor(s)01 / Lau, Catherine Y.
1 Decourcy Court
Unionville Ontario, M3L 246 / CA
[1990/18]
Representative(s)Fisher, Adrian John, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [1990/18]Fisher, Adrian John, et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date89311013.025.10.1989
[1990/18]
Priority number, dateUS1988026276026.10.1988         Original published format: US 262760
[1990/18]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0366451
Date:02.05.1990
Language:EN
[1990/18]
Type: A3 Search report 
No.:EP0366451
Date:15.01.1992
Language:EN
[1992/03]
Type: B1 Patent specification 
No.:EP0366451
Date:06.04.1994
Language:EN
[1994/14]
Search report(s)(Supplementary) European search report - dispatched on:EP26.11.1991
ClassificationIPC:A61K31/13, C07C217/40
[1990/18]
CPC:
A61K31/13 (EP); A61P37/06 (EP); C07C217/40 (EP);
C07C223/02 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1990/18]
TitleGerman:Verwendung von oxydierten Polyamiden, speziell NN'-Bis-(3-propionaldehyd)-1-4-diaminobutan als Immunsuppressiva[1990/18]
English:The use of oxidized polyamines, especially NN'-Bis-(3-propionaldehyde)-1-4-diaminobutane (sperminedialdehyde) as immunosuppressive agents[1990/18]
French:Utilisation des polyamides oxydés, en particulier NN'-Bis-(3-propionaldéhyde)-1-4-diaminobutane (spermine dialdéhyde) comme agents immunosuppresseurs[1990/18]
Examination procedure19.06.1992Examination requested  [1992/33]
09.09.1992Despatch of a communication from the examining division (Time limit: M04)
08.01.1993Reply to a communication from the examining division
19.05.1993Despatch of communication of intention to grant (Approval: Yes)
08.10.1993Communication of intention to grant the patent
01.12.1993Fee for grant paid
01.12.1993Fee for publishing/printing paid
Opposition(s)10.01.1995No opposition filed within time limit [1995/13]
Fees paidRenewal fee
10.10.1991Renewal fee patent year 03
09.10.1992Renewal fee patent year 04
11.10.1993Renewal fee patent year 05
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Documents cited:Search[X]JP46024365  ;
 [X]DE2908032  (NICHOLAS IND LTD)
 [X]  - BR. J CANCER, vol. 39, 1978, pages 548-557; J. M. GAUGAS et al.: "Evidence for serum binding of oxidized spermine and its potent G1-phase inhibition of cell proliferation".
 [AD]  - EUR. J. IMMUNOL., vol. 11, no. 3, 1981, pages 266-269; R. S. LABIB et al.: "Exzymatic oxidation of polyamines. Relationship to immunosuppressive properties".
 [AD]  - ISREAL J. MED. SCI., vol. 1, no. 4, 1965, pages 541-551; U. BACHRACH et al.: "Antiphage action of oxidized polyamines".
 [X]  - CHEMICAL ABSTRACTS, vol. 75, no. 19, 8th November 1971, page 190, abstract no. 117960c, Columbus, Ohio, US; & JP-A-46 024 365 (TAKEDA CHEMICAL INDUSTRIE, LTD) 13-06-1971, & JP46024365 A 00000000
ExaminationJP7124365
    - CHEMICAL ABSTRACTS, vol. 75, no. 19, 8th November 1971, page 190, abstract no. 117960c, Columbus, Ohio, US; & JP-A-71 24 365 (TAKEDA CHEMICAL INDUSTRIES, LTD) 13-06-1971, & JP7124365 A 00000000
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