Extract from the Register of European Patents

EP About this file: EP0343050

EP0343050 - 6-Phenyl-3-piperazinylalkyl 1H,3H-pyrimidinedione-2,4 derivatives, their preparation and their use in therapy [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.10.1993
Database last updated on 28.03.2026
Most recent event   Tooltip07.10.1993No opposition filed within time limitpublished on 24.11.1993 [1993/47]
Applicant(s)For all designated states
SYNTHELABO
22, Avenue Galilée
92350 Le Plessis Robinson / FR
[N/P]
Former [1992/30]For all designated states
SYNTHELABO
22, Avenue Galilée
F-92350 Le Plessis Robinson / FR
Former [1989/47]For all designated states
SYNTHELABO
22, avenue Galilée
F-92350 Le Plessis-Robinson / FR
Inventor(s)01 / Frost, Jonathan
23, Route de Montjean
F-91320 Wissous / FR
02 / Gaudilliere, Bernard
28, rue Zilina
F-92000 Nanterre / FR
03 / Rousseau, Jean
17Bis, Avenue de Montrouge
F-92340 Bourg la Reine / FR
04 / Dupont, Régis
152, Quai Paul Bert
F-37100 Tours / FR
05 / Manoury, Philippe
38, Avenue de Vaupépins
F-91370 Verrieres le Buisson / FR
06 / Obitz, Daniel
91, rue Boucicaut
F-92250 Fontenay aux Roses / FR
[1989/47]
Representative(s)Ludwig, Jacques, et al
SYNTHELABO, Service Brevets, B.P. 72
F-92352 Le Plessis-Robinson Cédex / FR
[N/P]
Former [1989/47]Ludwig, Jacques, et al
SYNTHELABO, Service Brevets, B.P. 72
F-92352 Le Plessis-Robinson Cédex / FR
Application number, filing date89401330.912.05.1989
[1989/47]
Priority number, dateFR1988000656817.05.1988         Original published format: FR 8806568
[1989/47]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report 
No.:EP0343050
Date:23.11.1989
Language:FR
[1989/47]
Type: B1 Patent specification 
No.:EP0343050
Date:02.12.1992
Language:FR
[1992/49]
Search report(s)(Supplementary) European search report - dispatched on:EP31.07.1989
ClassificationIPC:C07D239/54, C07D401/12, C07D217/22, A61K31/505
[1989/47]
CPC:
C07D239/54 (EP,US); C07D401/14 (KR); A61P25/04 (EP);
A61P25/06 (EP); A61P25/18 (EP); A61P25/20 (EP);
A61P25/24 (EP); A61P25/26 (EP); A61P9/12 (EP);
C07D401/12 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   DE,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1989/47]
TitleGerman:6-Phenyl-3-piperazinylalkyl-1H,3H-pyrimidindion-2,4-Derivate, deren Herstellung und Verwendung als Heilmittel[1989/47]
English:6-Phenyl-3-piperazinylalkyl 1H,3H-pyrimidinedione-2,4 derivatives, their preparation and their use in therapy[1989/47]
French:Dérivés de phényl-6 pipérazinyl-alkyl-3 1H,3H-pyrimidinedione-2,4, leur préparation et leur application en thérapeutique[1989/47]
Examination procedure21.08.1989Request for accelerated examination filed
15.05.1990Examination requested  [1990/28]
22.01.1991Despatch of a communication from the examining division (Time limit: M04)
22.01.1991Decision about request for accelerated examination - accepted: Yes
29.04.1991Reply to a communication from the examining division
31.01.1992Despatch of communication of intention to grant (Approval: Yes)
02.06.1992Communication of intention to grant the patent
06.08.1992Fee for grant paid
06.08.1992Fee for publishing/printing paid
Opposition(s)03.09.1993No opposition filed within time limit [1993/47]
Fees paidRenewal fee
18.04.1991Renewal fee patent year 03
06.04.1992Renewal fee patent year 04
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Documents cited:Search[A]   JOURNAL OF THE ORGANIC CHEMICAL SOCIETY, vol. C, no. 10, 1971, pages 1945-1948, Londres, GB; J. CLARK et al.: "Heterocyclic studies. Part XIX. Some 6-(substituted phenyl)-uracil and -thiouracil derivatives" [A]
 [A]   SYNTHESIS - JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, no. 1, janvier 1988, pages 70-72, Thieme Medical Publishers, Inc., New York, US; L. STREKOWSKI et al.: "Facile preparation of 6-substituted uracils" [A]
 [A]   CHEMICAL ABSTRACTS, vol. 106, 1987, page 650, rsum no. 102199w, Columbus, Ohio, US; M.M. AL-ARAB: "Reactions of arylpropiolamides with arylacetamides", & COLLECT. CZECH. CHEM. COMMUN. 1985, 50(12), 2910-13 [A]
Examination  J. MED. CHEM., vol. 29, no. 11, 1986, pages 2375-2380 [A]
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