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Extract from the Register of European Patents

EP About this file: EP0409281

EP0409281 - (R-(R*R*))-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl-3-phenyl-4((phenylamino)-carbonyl)-1H-pyrrole-1-heptanoic acid, its lactone form and salts thereof [Right-click to bookmark this link]
Former [1991/04](R-(R*R*))-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl-3-phenyl-4((phenylamino)-carbonyl)-1h-pyrolle-1-heptanoic acid, its lactone form and salts thereof
[2001/44]
StatusNo opposition filed within time limit
Status updated on  06.09.2002
Database last updated on 07.10.2024
Most recent event   Tooltip05.10.2005Change: Appeal number 
Applicant(s)For all designated states
WARNER-LAMBERT COMPANY
201 Tabor Road Morris Plains
New Jersey 07950 / US
[N/P]
Former [1991/04]For all designated states
WARNER-LAMBERT COMPANY
201 Tabor Road
Morris Plains New Jersey 07950 / US
Inventor(s)01 / Roth, Bruce David
6089 White Swan Lane
Ann Arbor, Michigan 48108 / US
[1991/04]
Representative(s)Henkel & Partner mbB
Patentanwaltskanzlei, Rechtsanwaltskanzlei
Maximiliansplatz 21
80333 München / DE
[N/P]
Former [2000/14]Henkel, Feiler, Hänzel
Möhlstrasse 37
81675 München / DE
Former [1991/04]Mansmann, Ivo
Gödecke AG Patentwesen Mooswaldallee 1-9
D-79090 Freiburg / DE
Application number, filing date90113986.520.07.1990
[1991/04]
Priority number, dateUS1989038418721.07.1989         Original published format: US 384187
[1991/04]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP0409281
Date:23.01.1991
Language:EN
[1991/04]
Type: B1 Patent specification 
No.:EP0409281
Date:31.10.2001
Language:EN
[2001/44]
Search report(s)(Supplementary) European search report - dispatched on:EP10.10.1990
ClassificationIPC:C07D207/327, C07D405/00, A61K31/40
[1991/04]
CPC:
C07D405/06 (EP,US); C07D207/327 (KR); A61P3/06 (EP);
A61P43/00 (EP); C07D207/34 (EP,US)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1991/04]
TitleGerman:[R-(R*R*)]-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl-3-phenyl-4-[(phenylamino)-carbonyl]-1H-pyrrol-1-heptansäure, ihre Lactonform und Salze davon[1991/04]
English:(R-(R*R*))-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl-3-phenyl-4((phenylamino)-carbonyl)-1H-pyrrole-1-heptanoic acid, its lactone form and salts thereof[2001/44]
French:Acide [(R-(R'R')]-2-(4-fluorophényl)-bêta,delta-dihydroxy-5-(1-méthyléthyl)-3-phényl-4-[(phénylamino)-carbonyl]-1H-pyrrole-1-heptanoique, sa forme lactonique et ses sels[1991/04]
Former [1991/04](R-(R*R*))-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl-3-phenyl-4((phenylamino)-carbonyl)-1h-pyrolle-1-heptanoic acid, its lactone form and salts thereof
Examination procedure20.07.1990Examination requested  [1991/04]
23.11.1993Despatch of a communication from the examining division (Time limit: M06)
25.05.1994Reply to a communication from the examining division
15.12.1994Despatch of a communication from the examining division (Time limit: M06)
21.06.1995Reply to a communication from the examining division
10.07.1996Date of oral proceedings
05.09.1996Despatch of communication that the application is refused, reason: substantive examination {1}
05.09.1996Minutes of oral proceedings despatched
22.05.2001Despatch of communication of intention to grant (Approval: No)
05.07.2001Despatch of communication of intention to grant (Approval: later approval)
05.07.2001Fee for grant paid
05.07.2001Fee for publishing/printing paid
30.08.2001Communication of intention to grant the patent
Appeal following examination29.10.1996Appeal received No.  T0229/97
09.01.1997Statement of grounds filed
31.10.2000Interlocutory revision of appeal
31.10.2000Result of appeal procedure: continuation of examination procedure
20.07.2000Date of oral proceedings
31.07.2000Minutes of oral proceedings despatched
Divisional application(s)EP00115656.1  / EP1061073
Opposition(s)01.08.2002No opposition filed within time limit [2002/43]
Fees paidRenewal fee
25.07.1992Renewal fee patent year 03
20.07.1993Renewal fee patent year 04
22.07.1994Renewal fee patent year 05
21.07.1995Renewal fee patent year 06
23.07.1996Renewal fee patent year 07
23.07.1997Renewal fee patent year 08
15.07.1998Renewal fee patent year 09
22.07.1999Renewal fee patent year 10
31.07.2000Renewal fee patent year 11
31.07.2001Renewal fee patent year 12
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Documents cited:Search[AD]US4681893  (ROTH BRUCE D [US])
    [ ] - JOURNAL OF MEDICINAL CHEMISTRY, vol. 28, 1985 G.E. STOKKER et al. "3- -Hydroxy-3-methylglutaryl- -coencyme A reductase inhibitors. 1. Structural modifica - tion of 5-substituted 3,5- -dihydroxypentanoic acids and their lactone derivatives" pages 347-358
    [ ] - TETRAHEDRON LETTERS, vol. 28, no. 8, 1987 J.E. LYNCH et al. "Synthesis of an HMG-COA reductase inhibitor; a diastereo- selective aldol approach" pages 1385-1388
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