Extract from the Register of European Patents

EP About this file: EP0381514

EP0381514 - Use of N-methyl-sphingosine as inhibitor of cell growth [Right-click to bookmark this link]
Former [1990/32]Sphingosine and N-methyl-sphingosine as inhibitor of cell growth
[1995/20]
StatusNo opposition filed within time limit
Status updated on  22.03.1996
Database last updated on 21.03.2026
Most recent event   Tooltip26.04.2002Lapse of the patent in a contracting state
New state(s): ES
published on 12.06.2002  [2002/24]
Applicant(s)For all designated states
The Biomembrane Institute
201 Elliott Avenue West Suite 305 Seattle
Washington 98119 / US
For all designated states
CORNELL RESEARCH FOUNDATION, INC.
Cornell Business & Technology Park 20 Thornwood Drive Suite 105
Ithaca, New York 14850 / US
For all designated states
MECT CORPORATION
P.O. Box 212, Mitsui Bldg. 5F, 2-1-1 Nishishinjuku
Tokyo 163 / JP
[N/P]
Former [1990/32]For all designated states
The Biomembrane Institute
201 Elliott Avenue West Suite 305
Seattle Washington 98119 / US
For all designated states
CORNELL RESEARCH FOUNDATION, INC.
Cornell Business & Technology Park 20 Thornwood Drive Suite 105
Ithaca New York 14850 / US
For all designated states
MECT CORPORATION
P.O. Box 212, Mitsui Bldg. 5F, 2-1-1 Nishishinjuku
Tokyo 163 / JP
Inventor(s)01 / Igarashi, Yasuyuki
2423 96th Ave, N.E.
Bellevue, Washington 98004 / US
02 / Toyokuni, Tatsushi
c/o The Biomembrane Institute, 201 Elliott Ave
West Seatttle, Washington 98119 / US
03 / Hakomori, Sen-itiroh
2024 80th S.E.
Mercer Island, Washington 98040 / US
04 / Racker, Efraim, Department of Biochemistry
239 BioTech, Cornell University
Ithaca, New York 14853 / US
05 / Fujita, Shuji
Mezon-do-Royal 206, 2-17-3, Kashiwa-cho
Tachikawashi, Tokyo / JP
06 / Sugimoto, Mamoru
26-8, Kamitakada 1-chome
Nakano-ku, Tokyo / JP
07 / Ito, Masayoshi
27-22-303, Fujimidai 1-chome
Kunitachi-shi, Tokyo / JP
08 / Shitori, Yoshiyasu
12-6-1307, Nishishinjuku, 6-chome
Shinjuku-ku, Tokyo / JP
09 / Ogawa, Tomoya
3-6-6-3-101 Kichiyojikitamachi
Musashino-shi, Tokyo / JP
[1990/32]
Representative(s)Woodcraft, David Charles, et al
Brookes Batchellor 102-108 Clerkenwell Road
London EC1M 5SA / GB
[N/P]
Former [1990/32]Woodcraft, David Charles, et al
BROOKES & MARTIN High Holborn House 52/54 High Holborn
London, WC1V 6SE / GB
Application number, filing date90301099.902.02.1990
[1990/32]
Priority number, dateUS1989030637803.02.1989         Original published format: US 306378
US1989039013507.08.1989         Original published format: US 390135
[1990/32]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0381514
Date:08.08.1990
Language:EN
[1990/32]
Type: A3 Search report 
No.:EP0381514
Date:17.07.1991
Language:EN
[1991/29]
Type: B1 Patent specification 
No.:EP0381514
Date:17.05.1995
Language:EN
[1995/20]
Search report(s)(Supplementary) European search report - dispatched on:EP30.05.1991
ClassificationIPC:A61K31/13
[1990/32]
CPC:
A61K31/13 (EP); A61P29/00 (EP); A61P35/00 (EP);
A61P35/04 (EP); A61P37/00 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1990/32]
TitleGerman:Verwendung von N-Methyl-Sphingosin als Zell-Wachstums-Inhibitor[1995/20]
English:Use of N-methyl-sphingosine as inhibitor of cell growth[1995/20]
French:Utilisation de la N-méthyl-sphingosine comme inhibiteur de la croissance cellulaire[1995/20]
Former [1990/32]Verwendung von Sphingosin und N-Methyl-Sphingosin als Zell-Wachstums-Inhibitor
Former [1990/32]Sphingosine and N-methyl-sphingosine as inhibitor of cell growth
Former [1990/32]Utilisation de la sphingosine et de la N-méthyl-sphingosine comme inhibiteur de la croissance cellulaire
Examination procedure09.01.1992Examination requested  [1992/11]
17.07.1992Despatch of a communication from the examining division (Time limit: M06)
12.01.1993Reply to a communication from the examining division
26.01.1993Despatch of a communication from the examining division (Time limit: M02)
25.03.1993Reply to a communication from the examining division
15.04.1993Despatch of a communication from the examining division (Time limit: M04)
14.06.1993Reply to a communication from the examining division
03.02.1994Despatch of communication of intention to grant (Approval: Yes)
19.08.1994Communication of intention to grant the patent
07.11.1994Fee for grant paid
07.11.1994Fee for publishing/printing paid
Opposition(s)20.02.1996No opposition filed within time limit [1996/19]
Fees paidRenewal fee
22.01.1992Renewal fee patent year 03
25.01.1993Renewal fee patent year 04
28.01.1994Renewal fee patent year 05
27.02.1995Renewal fee patent year 06
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Lapses during opposition  TooltipES17.05.1995
GR17.05.1995
[2002/24]
Former [2000/04]GR17.05.1995
Cited inExamination  SCIENCE, 1990, vol. 248, p. 1653-1656, Ghosh et al
   Biochemistry, 1989, vol. 28, p. 3138-3145, Merrill et al
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